Biomarkers Products & Reviews

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Biomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :

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GFAP Simoa Assay Kit

Quanterix

Glial Fibrillary Acidic Protein (GFAP) is a class-III intermediate filament majorly expressed in astrocytic glial cells in the central nervous system. Astrocytes play a variety of key roles in supporting, guiding, nurturing, and signaling neuronal architecture and activity. Monomeric GFAP is about 55kD. It is capable of forming both homodimers and heterodimers; GFAP can polymerize with other type III proteins or with neurofila…

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NEUROLOGY 2-PLEX B (Nf-L, GFAP*)

Quanterix

The Simoa Human Neurology 2-Plex assay (N2PB) measures two important neurology biomarkers in both cerebrospinal fluid (CSF) and blood. The two targets are neurofilament light (Nf-L) and glial fibrillary acidic protein (GFAP™), which have been studied as indicators of traumatic brain injury (TBI) severity. N2PB has been developed as a 2-Plex version of the Neurology 4-Plex B assay (N4PB). *Banyan GFAP™ is a registered tradem…

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STELLARIS SpectraPlex Microscope

Leica Microsystems Europe

SpectraPlex for STELLARIS is a comprehensive solution for 3D high-multiplex imaging in spatial biology. It provides a streamlined workflow to simplify panel creation, automate acquisition settings, and acquire data through advanced unmixing algorithms. With SpectraPlex you can ensure data quality and reliability across scales.

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IRDye Click Chemistry Reagents

LICORbio

IRDye® Click Chemistry reagents (DBCO, Alkyne, and Azide) offer convenient, versatile and reliable methods for biomolecule labeling. With a variety of in vitro and in vivo applications, from biomarker isolation to assay development.

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Ascent

Everest Biolabs

Automated extracellular vesicle isolation instrument Isolate extracellular vesicles effortlessly with size exclusion chromatography, enhancing productivity while minimizing operator errors. With the capacity to run multiple SEC columns simultaneously, it uniquely enables high-throughput exosome isolation, finally making large-scale clinical biomarker studies feasible.

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pTau-217 Assay

Quanterix

The Quanterix Simoa® ALZpath p-Tau 217 Assay provides an ultrasensitive, reliable solution for detecting phosphorylated Tau 217 (p-Tau 217) in blood. This critical biomarker is essential for Alzheimer’s research, offering insights into disease progression and helping differentiate Alzheimer’s from other forms of dementia.

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Recombinant FcγR and FcRn Proteins

Sino Biological

Sino Biological has developed a panel of recombinant Fc receptor products covering diverse isoforms and their mutants; these products can be utilized in various applications such as antibody screening, bioactivity assays during the CMC stage, consistency evaluation, and safety validation.

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MILLIPLEX® MAP Human Soluble Cytokine Receptor - Premixed 14 Plex

Merck

The MILLIPLEX®MAP Human Soluble Cytokine Receptor - Premixed 14 Plex is used for the simultaneous quantification of the following Human analytes: sCD30 (sTNFRSF8), sgp130, sIL-1RI (sCD121a), sIL-1RII (sCD121b), sIL-2Rα (sCD25), sIL-4R (sCD124), sIL-6R (sCD126), sRAGE, sTNFRI (sTNFRSF1A), sTNFRII (sTNFRSF1B), sVEGFR1 (sFlt-1), sVEGFR2 (sFlk-1), sVEGFR3 (sFlt-4), sEGFR

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MILLIPLEX® MAP Human Cytokine/Chemokine Magnetic Bead Panel II

Merck

The MILLIPLEX® MAP Human Cytokine/Chemokine Magnetic Bead Panel II is used for the simultaneous quantification of the following Human analytes: 6Ckine, BCA-1, CTACK, ENA-78, Eotaxin-2, Eotaxin-3, I-309, IL-16, IL-20, IL-21, IL-23, IL-28a, IL-33, LIF, MCP-2, MCP-4, MIP-1d, SCF, SDF-1A+β, TARC, TPO, TRAIL, TSLP

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