Epigenetic Analysis Products & Reviews

Get started with creating your own custom ChIP-on-Chip/Methylation microarrays easily by using SureDesign, Agilent’s online design tool. Choose from multiple array formats and focus on your specific research needs. You can design new probes using algorithms, upload your own sequences, or just select from our database of catalog probes.

Get started with creating your own custom ChIP-on-Chip/Methylation microarrays easily by using SureDesign, Agilent’s online design tool. Choose from multiple array formats and focus on your specific research needs. You can design new probes using algorithms, upload your own sequences, or just select from our database of catalog probes.

The Agilent SurePrint G3 Mouse Promoter Microarrays offer the same high sensitivity and accuracy provided by the earlier generation arrays but adds the benefits of extended coverage, updated content and increased cost savings. The Mouse Promoter Microarrays are optimized using probes validated for ChIP-on-chip technology and are proven to deliver the robust hybridization and optimal binding critical to reliable data. They are…

The Agilent SurePrint G3 Mouse Promoter Microarrays offer the same high sensitivity and accuracy provided by the earlier generation arrays but adds the benefits of extended coverage, updated content and increased cost savings. The Mouse Promoter Microarrays are optimized using probes validated for ChIP-on-chip technology and are proven to deliver the robust hybridization and optimal binding critical to reliable data. They are…

The Agilent SurePrint G3 Mouse Promoter Microarrays offer the same high sensitivity and accuracy provided by the earlier generation arrays but adds the benefits of extended coverage, updated content and increased cost savings. The Mouse Promoter Microarrays are optimized using probes validated for ChIP-on-chip technology and are proven to deliver the robust hybridization and optimal binding critical to reliable data. They are…

The Agilent SurePrint G3 Mouse Promoter Microarrays offer the same high sensitivity and accuracy provided by the earlier generation arrays but adds the benefits of extended coverage, updated content and increased cost savings. The Mouse Promoter Microarrays are optimized using probes validated for ChIP-on-chip technology and are proven to deliver the robust hybridization and optimal binding critical to reliable data. They are…

The Agilent SurePrint G3 Mouse Promoter Microarrays offer the same high sensitivity and accuracy provided by the earlier generation arrays but adds the benefits of extended coverage, updated content and increased cost savings. The Mouse Promoter Microarrays are optimized using probes validated for ChIP-on-chip technology and are proven to deliver the robust hybridization and optimal binding critical to reliable data. They are…

The Agilent SurePrint G3 Mouse Promoter Microarrays offer the same high sensitivity and accuracy provided by the earlier generation arrays but adds the benefits of extended coverage, updated content and increased cost savings. The Mouse Promoter Microarrays are optimized using probes validated for ChIP-on-chip technology and are proven to deliver the robust hybridization and optimal binding critical to reliable data. They are…

Agilent’s mouse CpG microarrays enable a comprehensive insight into the DNA methylation changes that may be correlated to key biological processes. Such processes include cancer, development, genomic imprinting, gene silencing, and chromatin stability.

Agilent’s Human ENCODE ChIP-on-chip microarray is designed to identify human DNA binding proteins within the ENCODE regions. The microarray is designed to target ENCODE regions with more than 53,000 validated probes, which are proven to deliver robust hybridization and optimal binding critical to reliable data.

Agilent SureSelectXT Human Methyl-Seq is the first comprehensive target enrichment system to enable researchers to focus on the regions where methylation is known to impact gene regulation. It targets the most complete Methyl-Seq content, including cancer tissue-specific DMRs, GENCODE promoters, CpG islands, shores and shelves ±4kb, DNaseI hypersensitive sites and RefGenes. • Delivers more information than methylation microarr…

eArray is a web-based application that enables you to harness the flexibility of Agilents SurePrint oligo manufacturing technology in the creation of custom microarray designs and oligo libraries.  eArray, free to all registered users, allows you to create assays that are specific to your research needs. Create custom microarray designs for Gene Expression, microRNA, Model Organisms, CGH, ChiP-on-chip, and DNA Methylation.Crea…

The MethylEdge™ System provides an efficient method to rapidly perform bisulfite conversion with minimal DNA fragmentation, giving you more intact, converted DNA for downstream applications.   Start with as little as 100pg of input DNA for those precious, limited samples. Use the MethylEdge™ System with other DNA Methylation Workflow reagents to perform sensitive DNA methylation analysis on many sample types. The rapi…

BisCap® Human CpG Island Panel is targeted for detection of methylation status of 27,000 CpG island and also covers 13 commercial methylation markers. The panel could be widely used in methylation marker screening, early tumor screening, early detection, and etc.

Novogene provides Whole Genome Bisulfite Sequencing (WGBS), Reduced Representation Bisulfite Sequencing (RRBS), Chromatin Immunoprecipitation Sequencing (ChIP-seq), RNA Immunoprecipitation Sequencing (RIP-seq), and Assay for Transposase-Accessible Chromatin Sequencing (ATAC-seq), tailored for both bulk and single-cell samples.

Your partner from discovery to therapeutics

Clara® HRM Mix delivers maximum specificity to your high resolution melt (HRM) curve analyses. Accurately detect genetic mutations, quickly identify genotypes based on SNPs, or calculate percent methylation of a target region with HRM analysis.

Your single solution for multiomics data - Uncover a true 6-base genome for unprecedented insights into current and future biological states. Access all four canonical bases and distinguish 5‑methylcytosine (5mC) and 5‑hydroxymethylcytosine (5hmC) from a single 5ng DNA sample, in a single experiment, with high accuracy.

The H2A.X Phosphorylation Assay Kit (Flow cytometry) is a cell based assay formatted for flow cytometric detection of levels of phosphorylated Histone H2A.X. Cells are cultured in microplates, treated with agents that induce DNA damage or apoptosis, which stimulates H2A.X phosphorylation. Cells are then fixed and permeabilized in preparation for staining and detection. Histone H2A.X phosphorylated at serine 139 is detected by…

This kit contains nonradioactive components for radiolabeling and purifying histone H4 peptide with [3H]-acetyl CoA. The radiolabeled peptide is a suitable substrate for assay of HDAC activity. HeLa nuclear extract, which is rich in histone deacetylase activity, is included as a positive control. The HDAC inhibitor sodium butyrate is provided to demonstrate specificity of the deacetylase activity.

Accessory reagent kit for the analysis of histone methyltransferase activity.

This assay is a simple two-step procedure performed in a microtiter plate. In the first step samples are incubated with the HDAC assay substrate, allowing deacetylation of the fluorometric substrate. Next, Activator Solution releases a fluorophore from the deacetylated substrate or standard.

Chromatin Immunoprecipitation (ChIP) is an important technique allowing the researcher to analyze in vivo interactions of proteins with genomic DNA. Any chromatin-associated or DNA binding protein can be analyzed with this technique, provided a good antibody to the protein exists. One can measure different proteins localized to a specific region of the genome, or the genome wide distribution of a specific protein. Another powe…

The 384 well format kit is a newer version of the tried and true non-radiographic HDAC assay. As in the previous kit, samples are first incubated with the HDAC Assay substrate, allowing deacetylation of the fluorometric substrate. After incubation, the activator solution is added, and releases a fluorophore from the deacetylated substrate or standard. The sample is then put into a microplate reader and fluorescence (i.e free/c…