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ChemiSCREEN™ NTR1 Calcium-Optimized FLIPR Cell Line

Merck

Chemicon's cloned human NTR1-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant NTR1 expression on the cell surface and contains high levels of the promiscuous G protein Galpha15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between NTR1 and neurotensin.

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ChemiSCREEN™ CCR9 Calcium-Optimized FLIPR Cell Lines

Merck

Chemicon's cloned human CCR9-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant CCR9 expression on the cell surface and contains high levels of the promiscuous Galpha15 protein to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between CCR9 and its ligands.

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ChemiScreen™ Calcium-Optimized Stable Cell Line Human Recombinant D2 Dopamine Receptor

Merck

Chemicon's cloned human D2L-expressing cell line is made in the Chem-7 host, which supports high levels of recombinant D2 expression on the cell surface and contains high levels of the promiscuous G protein to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between D2 and its ligands.

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ChemiSCREEN™ Human Recombinant APJ Apelin Receptor Calcium-Optimized Stable Cell Line

Merck

EMD Millipore’s cloned human APJ-expressing cell line is made in the Chem-5 host, which supports high levels of recombinant APJ expression on the cell surface and contains optimal levels of promiscuous G protein to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for agonists and antagonists at APJ.

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ChemiSCREEN™ Human Recombinant NMU2 Neuromedin U Receptor Calcium-Optimized Stable Cell Line

Merck

EMD Millipore’s cloned human NMU2-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant NMU2 expression on the cell surface and contains high levels of the promiscuous G protein to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for agonists and antagonists at NMU2.

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ChemiScreen™ Human D1 Dopamine Receptor Calcium-Optimized FLIPR Cell Line

Merck

Chemicon's cloned human D1-expressing cell line is made in the Chem-6 host, which supports high levels of recombinant D1 expression on the cell surface and contains high levels of the promiscuous G protein to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between D1 and its ligands.

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ChemiSCREEN™ Human Recombinant M4 Muscarinic Acetylcholine Receptor Calcium-Optimized Stable Cell Line

Merck

Chemicon's cloned human M4 -expressing cell line is made in the Chem-4 host, which supports high levels of recombinant M4 expression on the cell surface and contains high levels of the promiscuous G protein to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between M4 and its ligands.

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ChemiScreen™ Human Recombinant EP4 Prostanoid Receptor Calcium-Optimized Stable Cell Line

Merck

Chemicon's cloned human EP4-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant EP4 expression on the cell surface and contains high levels of the promiscuous G protein Gα15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for agonists and antagonists at EP4.

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ChemiSCREEN™ Human Recombinant EP2 Prostanoid Receptor Calcium-Optimized Stable Cell Line

Merck

Chemicon's cloned human EP2-expressing cell line is made in the Chem-9 host, which supports high levels of recombinant EP2 expression on the cell surface and contains high levels of the promiscuous G protein to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between EP2 and its ligands.

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ChemiSCREEN™ Human Recombinant S1P4 Lysophospholipid Receptor Calcium-Optimized Stable Cell Line

Merck

Chemicon's cloned human S1P4-expressing cell line is made in the Chem-5 host, which supports high levels of recombinant S1P4 expression on the cell surface and contains high levels of the promiscuous G protein to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between S1P4 and its ligands.

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ChemiSCREEN™ Human Recombinant GPR92 / LPA5 Lysophospholipid Receptor Calcium-Optimized Stable Cell Line

Merck

EMD Millipore’s cloned human GPR92 -expressing cell line is made in the Chem-1 host, which supports high levels of recombinant GPR92 expression on the cell surface and contains high levels of the promiscuous G protein to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for agonists and antagonists at GPR92.

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ChemiSCREEN™ Human Recombinant GPR91 Succinate Receptor Calcium-Optimized Stable Cell Line

Merck

EMD Millipore’s cloned human GPR91 -expressing cell line is made in the Chem-1 host, which supports high levels of recombinant GPR91 expression on the cell surface and contains high levels of the promiscuous G protein to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for agonists and antagonists at GPR91.

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Ingenio® Cell Droppers

Mirus Bio LLC

High efficiency electroporation using any instrumentElectroporation using Ingenio Electroporation Kits and Solution affords increased gene expression in several different cell types with minimal toxicity.Ingenio® Cell Droppers Features:•High efficiency electroporation of hard to transfect cell lines and primary cells•Compatible with most conventional electroporation devices including Lonza-Amaxa®, Bio-Rad® or Harvard BTX®•Idea…

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Competent Cells

Merck

The most common method for transformation of plasmids into E. coli is to use chemically competent cells. Although competent cells can be prepared in the laboratory, greater efficiency, reproducibility and convenience are achieved using prepared competent cells. Novagen offers the widest selection of competent cells available for protein expression. Our strains offer a variety of options that enable you to maximize the yield an…

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NEBNext® Quick DNA Library Prep Master Mix Set for 454™

New England Biolabs Inc.

The NEBNext Quick DNA Library Prep Master Mix Set for 454 contains enzymes and buffers in convenient master mix formulations that are ideally suited for sample preparation for next-generation sequencing, and for preparation of expression libraries. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expressio…

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Octet® Anti-CHO Host Cell Protein (HCP) Detection

Sartorius Group

Host cell proteins (HCPs) are contaminants found in biopharmaceuticals expressed in bacterial, yeast or mammalian production cell lines. Among protein expression cell lines, Chinese hamster ovary (CHO) cells are the most commonly used mammalian hosts for industrial production of recombinant protein therapeutics. However, manufacturing and production processes of biopharmaceuticals often leave behind contaminating HCPs fr…

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pCMV-3Tag-6 vectors

Agilent Technologies

The pCMV-3Tag vectors are a series of epitope tagging mammalian expression vectors featuring three copies of the epitope tag in a variety of configurations. pCMV-Tag vectors have a single copy of the available epitope tags, resulting in weaker tagging.  Stronger signal in immunological assays  Small tags do not interfere with functional analysis studies  Three reading frames for both N- and C- terminus tags

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pCMV-3Tag-7 vectors

Agilent Technologies

The pCMV-3Tag vectors are a series of epitope tagging mammalian expression vectors featuring three copies of the epitope tag in a variety of configurations. pCMV-Tag vectors have a single copy of the available epitope tags, resulting in weaker tagging.  Stronger signal in immunological assays  Small tags do not interfere with functional analysis studies  Three reading frames for both N- and C- terminus tags

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pCMV-3Tag-8 vectors

Agilent Technologies

The pCMV-3Tag vectors are a series of epitope tagging mammalian expression vectors featuring three copies of the epitope tag in a variety of configurations. pCMV-Tag vectors have a single copy of the available epitope tags, resulting in weaker tagging.  Stronger signal in immunological assays  Small tags do not interfere with functional analysis studies  Three reading frames for both N- and C- terminus tags

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pCMV-3Tag-9 vectors

Agilent Technologies

The pCMV-3Tag vectors are a series of epitope tagging mammalian expression vectors featuring three copies of the epitope tag in a variety of configurations. pCMV-Tag vectors have a single copy of the available epitope tags, resulting in weaker tagging.  Stronger signal in immunological assays  Small tags do not interfere with functional analysis studies  Three reading frames for both N- and C- terminus tags

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ChemiSCREEN™ Human Recombinant CXCR1 Chemokine Receptor Calcium-Optimized Stable Cell Line

Merck

Chemicon's cloned human CXCR1-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant CXCR1 expression on the cell surface and contains high levels of the promiscuous G protein Gα15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between CXCR1 and its ligands.

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ChemiSCREEN™ CXCR2 Calcium-Optimized FLIPR Cell Line

Merck

Chemicon's cloned human CXCR2-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant CXCR2 expression on the cell surface and contains high levels of the promiscuous G protein Galpha15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between CXCR2 and its ligands.

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ChemiSCREEN™ Human Recombinant CXCR3 Chemokine Receptor Calcium-Optimized Stable Cell Line

Merck

Chemicon’s cloned human CXCR3-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant CXCR3 expression on the cell surface and contains high levels of the promiscuous G protein G16 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between CXCR3 and its ligands.

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