ADME-Toxicology Products & Reviews

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ADME-toxicology (ADME-Tox) studies are used in pharmacology and pharmacokinetics to assess the activity/toxicity of drugs <i>in vivo</i> or <i>in vitro</i>. Find bioassays for absorption, distribution, metabolism, and excretion of drug molecules including cytotoxicity, transporter/permeability, metabolism and activity assays as well as hepatocytes and cell lines for ADME. Find the best ADME-toxicology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Trypan Blue

Bio-Rad

10 x 1.5 ml, sufficient for 1,500 counts (10 µl/count), 0.4% in 0.81% sodium chloride and 0.06% potassium phosphate dibasic solution, sterile filtered, for use with TC10™ or TC20™ automated cell counter.

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CFDA-SE

Bio-Rad

Use the CFDA-SE (5[6]Carboxyfluorescein diacetate, succinimidyl ester) cell-permeable dye to monitor cell population health.

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ReadiDrop™ Propidium Iodide

Bio-Rad

Commonly used in flow cytometry experiments for excluding dead cells, the propidium iodide solution enters a compromised cell and binds to double-stranded DNA/RNA by intercalating between base pairs.

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ReadiDrop™ 7-AAD

Bio-Rad

The ReadiDrop™ 7-aminoactinomycin D (7-AAD) cell viability assay is designed as a ready-to-use 7-AAD solution, which binds double-stranded DNA with a high-affinity intercalation between GC base pairs.

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ADCC Reporter Bioassay

Promega Corp.

Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism of action of antibodies through which virus-infected or other diseased cells are targeted for destruntion by components of the cell-mediated.

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HybridSPE®-Plus Plates

Merck

Our HybridSPE ® -PLus plates effectively remove phospholipids and proteins from biological matrices in a simple pass-through method for accurate and reproducible LC-MS analysis. Unlike other phospholipid removal SPE products on the market, the unique retention mechanism of HybridSPE ® allows for separation of even very hydrophobic analytes from phospholipid contaminants.     

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