Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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P-97 Flaming/Brown Type Micropipette Puller

AutoMate Scientific Inc.

The Model P-97 micropipette puller is the latest generation of the Flaming/ Brown type puller for fabrication of micropipettes, patch pipettes and microinjection needles. While retaining many of the features on the Model P-87, the P-97 offers improvements in mechanical, electronic and software design. The result is better control of the pulling process and a higher degree of reproducibility. The P-97 combines a proven mechanic…

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Eclipse Workstation

J-KEM Scientific, Inc.

The Eclipse workstation is easily customized and available with 1 to 5 addressable axes. Two axis (X,Y) workstations start under $10,000. The Eclipse is offered either as the robot only, for customers who want to program their own application, or fully programmed for standard or custom applications.

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Corning® 96-well Clear V-Bottom Polypropylene Not Treated Microplate, 25 per Bag, without Lids, Sterile

Corning Life Sciences

Feature uniform skirt heights for greater robotic gripping surface Solvent resistant polypropylene provides compatibility with many common organic solvents (e.g., DMSO, ethanol, methanol) Sterile and DNase- and RNase-free Total volume is 320 µL; recommended working well volume is 75 to 200 µL Without lids; lids, sealing mats and tapes supplied separately

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Pippin Prep DNA Size Selection System

Sage Science

The Pippin Prep is a preparative electrophoresis platform for collection of size-selected DNA samples. The system automates DNA size selection using disposable, pre-cast agarose cassettes to extract fractions according to user-defined software input. Samples are electro-eluted from agarose and collected in buffer. The platform is used for the construction of next-gen sequencing libraries. The system collects fragments (depend…

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P-30 Vertical Micropipette Puller

Sutter Instrument Co.

The model P-30 vertical micropipette puller is designed for the fabrication of basic micropipettes and patch-type pipettes. It will pull micropipettes with tip diameters as small as 0.3um and moderate taper lengths (10 to 15mm). By using an included patching attachment, the P-30 will pull the standard double pull patch-type pipette. Used with thin wall glass capillaries, it will generate pipettes or needles suitable for microi…

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Biochrom EZ Read 400 Flexi Microplate Reader

Biochrom Ltd

The Biochrom EZ Read 400 Flexi is an economically priced, easy-to-use microplate reader for 96-well plates, quick to set up and requiring minimal training. The simple, robust PC-controlled microplate reader has no un-necessary features and is ideally suited to labs with multi-level users performing absorbance assays The instrument is supplied with ADAP Basic PC software which is used for instrument control and to export of raw…

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Jumbosep™ Centrifugal Devices

Pall Life Sciences - Laboratory, Food, Beverage

Convenient and reliable concentration, purification, and diafiltration of 20 to 60 mL biological samples with Pall Life Science's Jumbosep Advance Centrifugal Devices Features of the Macrosep Advance Centrifugal Devices:  •  Typically concentrates 60 mL sample volumes to 5 mL in 30 minutes.    •  Provides high recoveries, typically > 90%.   •  Low protein-binding Omega membrane and polypropylene housing minimize losses due to…

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AcroPrep™ Advance Filter Plates for Protein Purification

Pall Life Sciences - Laboratory, Food, Beverage

AcroPrep™ Advance Filter Plates- Advancing sample preparation Features of the AcroPrep™ Advance Filter Plates:  •  Smooth well design – Provides consistency in filtration times, as well as efficient sample and bead recovery.   •  Optimized outlet tips – Minimizes sample leakage during incubation steps and reduces the presence of hanging drops following filtration.   •  New well geometry – Results in faster , more uniform filt…

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Vacuum Manifold and Accessories

Pall Life Sciences - Laboratory, Food, Beverage

Pall Life Sciences Vacuum Manifold - Designed to perfectly fit SBS-conforming filter plates Comes complete with the necessary O-ring and gasket. The control block includes the vacuum pressure gauge, vacuum metering valve, vacuum release valve, and the 1/4 inch hose barb for vacuum line attachment. Includes a Delrin spacer block designed for standard 350 µL receiver plates. The spacer block has been optimized to reduce the spac…

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Fractional Distillation Systems

Pope Scientific Inc.

Fractional Distillation Systems for Purification, Fractionation, and Solvent Recovery The ideal separation of volatile components (fractionation) can be achieved using Pope's state-of-the-art line of fractional distillation systems, (Fractional Columns). Fractional distillation is particularly suitable for critical applications that require separation of complex mixtures such as fine chemicals, pharma- ceuticals, foods, flav…

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RapidFire Epigenetic Assay Development & Screening Services

Assays for methylases, acetylases, phosphorylases and other modifying enzymes involved in histone and chromatin modulation are developed and optimized by RapidFire scientists for primary and secondary screens. Although histone modifying enzymes can be difficult to analyze by traditional methods, label-free RapidFire technology is well suited to this novel and emerging class of targets.

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True North® Cryogenic Vials

Heathrow Scientific

Innovative design saves space in your freezer! We have designed the first externally threaded vials that fit 100 to a standard cryostorage box, so you use freezer space 23% more efficiently as compared with leading cryogenic vial brands. Each vial has extra-thick walls for superior puncture and rupture protection, imprinted writing area, graduation marks, silicone rubber seal ring, and self-standing base. Unique lid (patent pe…

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Thermo Scientific ExactFinder Software for MS

Thermo Fisher Scientific

Thermo Scientific ExactFinder software, used with an Exactive or Orbitrap series high-performance liquid chromatography/mass spectrometry system, allows food and environmental safety, clinical research and forensic toxicology laboratories to attain high productivity and confidence in routine targeted and general unknown screening applications—with remarkable ease. ExactFinder software offers a single streamlined workflow for…

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Corning® 96-well Black Flat Bottom Polystyrene Not Treated Microplate, 25 per Bag, without Lid, Nonsterile

Corning Life Sciences

Has low background fluorescence and minimize light scattering Designed to reduce well-to-well crosstalk Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the immobilization of large molecules, such as antibodies, that have large hydrophobic regions that can interact with the surface Untreated microplates have a bindin…

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Cellject Uno

Thermo Fisher Scientific

The Cellject Uno Electroporator is simple and easy to use. It is ideal for producing maximum efficiencies in bacterial applications. The user simply selects one of two voltages and either one mm, two mm or four mm cuvettes and then presses a button.Product detail:The Cellject Uno Electroporator is a simple, easy to use electroporator for producing optimum efficiencies in bacterial and yeast applications.  The user simply selec…

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Cellject Duo

Thermo Fisher Scientific

The Cellject Elecroporator is suitable for all cell types including embryo, mammalian, plant, yeast and bacterial. Its has highly user-freindly programing and can be used remotely, for example in a laminar flow hood, and operated by remote control.Product detail:The Cellject Duo Electroporator efficiently transfects embryo, mammalian, plant, yeast and bacterial cells.  The design facilitates ease of operation without compromiz…

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Precision Universal Cuvettes

Thermo Fisher Scientific

The Thermo Electroporation cuvettes are designed to maximize your transfection results and improve sample handling.  We aim to provide you with a total solution for your electroporation needs, and not only supply instruments and consumables - we give you protocol support tailored to your specific application. Product detail:Thermo Hybaid cuvettes have been manufactured to strict quality control criteria whilst maximising desig…

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Bottle and Mesh System

Thermo Fisher Scientific

Thermo's hybridisation bottles are manufactured using thick walled boro-silicate glass which absorbes over 90% of ß-emissions ensuring safe and easy handling.  Every oven is supplied with a bottle gripper free of charge.  The rubber sleeve increases user safety by protecting the user from burns as well as giving a better grip during manipulations. An optional mesh system for easy membrane handling is also available. Product d…

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