Drug discovery > Target Discovery Products & Reviews

Test set for comparison of Magnet Assisted Transfection versus Magnet Assisted Lipofection. Including a one-month-rent of a universal magnet plate. Optimized for siRNA transfections. Magnet Assisted Transfection (MATra) is a new, easy-to-handle, very fast and highly efficient technology to transfect cells in culture. Data from a variety of species using cell lines or primary tissue culture have accumulated including human, mon…

The NorDiag Bullet instrument is CE IVD ready and provides TRUE walk away automated sample preparation for molecular diagnostics. The NorDiag Bullet is compact yet flexible, designed to provied targetend solutions for the user's needs.

The BioSorter is a large particle flow cytometer designed to analyze, sort and dispense biological materials and other objects ranging in size from 10 to 1500 microns in diameter. The system is designed to handle objects which are too large or too fragile for traditional flow cytometers. Examples include small multicellular model organisms, delicate large cells / cell clusters, small seeds and beads used as microcarriers or fo…

USP Apparatus 4 Product Details:• Cells designed for MR, CR and ER tablets, capsules, suppositories, powders, pellets, APIs, implants, medical devices, ophtalmic devices, drug eluting stents, creams, gels, suspensions, microspheres, liposomes and nanospheres • Suitable for R&D and QC, manual and automated sampling, firmware or software driven, linked to UV, UVFO (UV Fiber Optic) and fraction collector for HPLC • Evolution of t…

Universal Caps - Seal multiple size tubes with one size cap. Easy to use, polyethylene caps feature a universal fit. Seal caps with one handed use. Caps provide tight, leak-proof seal for standard glass or plastic tubes. The innovative design of the Heathrow Scientific Universal Caps fit larger tube sizes inverted and smaller tube sizes upright. Compatible with tube sizes 10 mm, 12/13 mm or 16 mm. Available in Blue, Green, Red…

Disposable L-Shaped Cell Spreaders The smooth surface of heathrow Scientific Disposable L-Shaped Cell Spreaders will not tear agar plate or disturb media layer. Made from ABS plastic and measuring 146 x 38 mm; 4 mm diameter. Disposable L-Shaped Cell Spreaders come sterile in a bag of 10 for immediate use without flaming.

Disposable Delta™ Cell Spreader The uniquely shaped Disposable Delta™ Cell Spreader has an innovative edgeless design—no need to worry about tearing the agar. The Heathrow Scientific Disposable Delta™ Cell Spreader has a delta-shaped head distributes pressure evenly for smooth spreading. Handle flexes slightly under pressure and is rippled for easy manipulation. Sterile ABS Disposable Delta™ Cell Spreaders are individually bag…

The InviGenius provides advanced and reliable performance in automated nucleic acid sample preparation in combination with the well established magnetic bead based InviMag technology for DNA and RNA purification – especially for increased standardization and streamlined laboratory workflows. Innovative functions and optimized protocols enable reliable results of high quality. The InviGenius automated system, with built-in touc…

Blue Sky Biotech's TDA 2.0™ is a stable lipid-based nanoparticle with nickel-chelating moieties for use in assembling purified histidine-tagged proteins which are normally membrane associated. TDA 2.0™ allows scientists to study membrane-associated proteins in a way that restores the essential biological environment created by the cell membrane. This synthetic template restores the organizing features of the membrane without t…

Flasks Nunclon™Δ Surface • Cell culture flasks with surface areas from 25-175 cm² • Filter caps or vent/close caps available for good gas exchange • Extra caps included in every carton • Short, wide neck for easy access • Individually leak tested • Excellent optical quality • Nunclon™Δ certified • Barcoded 175 cm² with large Code 128

HENDRIX SM100 - Programmable Ultrasonic Microplate Fluid ProcessorFeatures of the HENDRIX SM100 system: • Processes 24, 96, 384, 1536 and 3456-well polypropylene, polystyrene, and COC SBS format microplates • Compact, modular design - efficient for integration/stand-alone use      - Fluid processor unit occupies about ½ sq. ft. of deck space (W: 8.25" D: 8.75" H: 4.25")      - Base control unit easily sits underneath lab bench…

Cell Membranes - Custom Preparation of Cell Membranes from CCS Cell Culture Service Preparations membranes from cell which are expressing a target receptor, transporter or ion channel at a high density are a useful tool in drug research. Embedded in a membrane fragment or vesicle the proteins remain in a functional native confirmation. Ligand binding assay and functional GTP-gammaS assays can be performed with these preparati…

Components of the Upstate (Millipore) Casein Kinase 2 Assay Kit:• Casein Kinase 2 Substrate Peptide (Cat.# 12-330) • Assay Dilution Buffer I (ADBI) (Cat.# 20-108) • PKA Inhibitor Cocktail (Cat.# 20-114) • Magnesium/ATP Cocktail (Cat.# 20-113) • P81 Phosphocellulose Squares (Cat.# 20-134) For use to measure the phosphotransferase activity of Casein Kinase 2 (CK-2) in immunoprecipitates and column fractions based on phosphorylat…

Thermo Scientific* LTQ FT Ultra combines the most advanced Ion Trap and Fourier Transform Ion Cyclotron Resonance technologies into a single instrument with unprecedented analytical power and versatility. Ultra-high resolution and sensitivity coupled with sub ppm mass accuracy, and MSn are universally available for the toughest applications demanding rigorous structural characterization.

HyClone Classical Liquid Media: BME/EBSS Thermo Scientific HyClone Classical Liquid Media: BME/EBSS is manufactured using ISO 9001:2000-certified processes. High yield cultures begin with high quality media. In order to maintain these standards, all HyClone products as well as raw material components must pass strict Quality Control testing to confirm the appropriate level of quality. Each raw material has a specification docu…

TransIT®-LT1 Transfection Reagent from Mirus Bio- A broad spectrum, low toxicity, DNA transfection reagent • Broad Spectrum DNA Delivery - Utilize one transfection reagent and protocol for a variety of cells. • Low Cellular Toxicity - Maintain cell density and reduce experimental biases. • High Efficiency Delivery - Achieve expression in a large population of cells for experimental success. • Deliver Single or Multiple Plasmi…

The Recording Nanoject II: Enables High Precision Electrophysiological Guidance of Nanoliter Injections into the Brain Features of the Drummond Scientific Recording Nanoject II include:• Facilitates connection to an extracelluar amplifier to allow recording of neural activity • Supplements stereotaxic coordinates in guiding the placement of small injections • Provides direct displacement of neuronal tracer or excitotoxin fro…

SCOPE, Structure-based compound optimization prioritization and evolution is an innovation from VLife to overcome challenges in lead optimization. SCOPE provides the user a way to address known problems like poor correlation between energy and activity, insensitive docking scoring functions for molecule prioritization and insufficient clues in ligand design for improvement in activity. SCOPE smartly understands the information…

R & D Systems Active STAT3 DuoSet IC® Kit - For the development of transcription factor assays to measure human and mouse active STAT1 p91. The R & D DuoSet IC Phospho-specific ELISA format is a sensitive and convenient phosphorylation assay for use with cell lysates. The DuoSet IC signal transduction assays are an excellent alternative to Western blot, especially when used in combination with DuoSet IC ELISAs designed to mea…

R&D Oncostatin MOncostatin M (OSM) is a member of the IL-6 subfamily of cytokines that includes IL-6, IL-11, LIF, CNTF, CLC, and Cardiotrophin-1. These cytokines have overlapping biological functions and shared receptor components. Mouse OSM protein shows 48% amino acid identity with human OSM.

AcroPrep™ Advance filter plates are the newest edition to Pall’s filter plate family. New sealing technology and advanced tip design make these the first choice in critical sample prep applications.   Aplications: Lysate Clearance DNA purification Protein purification Multiplex assays Aqueous filtration Particulate removal Size exclusion Bead-based assays Neonatal screening Flow cytometry S…

AcroPrep™ Advance Filter Plates for Ultrafiltration Provides rapid, efficient separation of biomolecules. Omega™ membrane provides high recovery and typically results in > 90% recovery of target biomolecules. New well design results in faster, more uniform filtration rates across the plate with reduced hold-up volume for maximum sample recovery Intrinsic plate and membrane properties prevent target molecules from binding to th…

Using the LiChrolut® extraction unit simplifies solid-phase extraction and makes it more rapid and reliable. The drying attachment speeds up the drying process under controlled conditions. All the individual steps associated with solid-phase extraction can be carried out using the LiChrolut® extraction unit.

Solid-phase extraction for increased productivity: LiChroPLATE® microtiter plates improve the sample throughput and speed of sample preparation. LiChroPLATE® enables solid-phase extraction to be carried out with considerable convenience and flexibility. From sample application with multi-channel pipettors to complete automation of the sample preparation process. Only in this way high sample throughputs can be achieved. LichroP…

Enhanced selectivity for polar analytes: LiChroPLATE® EN microtiter plates for solid-phase extraction shortens sample preparation time up to 75% compared with other polymer phases. By using LiChroPLATE® EN in combination with an 8-channel pipettor, it is possible to extract 96 samples in less than half an hour. EN stands for enhanced selectivity with respect to all polar analytes – whether basic, neutral or acidic. Even for la…