Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Erlenmeyer Flask

Accumax

Accumax Erlenmeyer Flask- the perfect solution for suspension culture of mammalian cells, plants, microbes and microorganisms. These flasks are not only ideal for containing, mixing and storing solutions, but also offer a safer alternative to glass. With their durable construction, they won't break, chip or shatter during the hustle and bustle of everyday lab work.  

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Phase Separator™

Tecan

Phase Separator is a unique, new pipetting capability on the Fluent® Automation Workstation. This patented liquid separation technology can detect liquid-liquid interfaces and effectively separate neighbor phases while avoiding contamination. Suitable for removing the plasma phase from a centrifuged blood sample, it delivers up to double the speed of camera-based systems for plasma separation.

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Nucleus® Automation Infrastructure

HighRes Biosolutions

As the framework of stellar automation, Nucleus®  Automation Infrastructure combines (A) your choice of stationary or mobile mounted collaborative robotic arms; (B) mobile cart or stationary table work surfaces to house your preferred devices; and (C) powerful Cellario™ Whole Lab Automation software. Unique MicroDock technology lets you effortlessly roll workflow devices in and out for space efficiency and manual device use.

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Prime® Automated Liquid Handler

HighRes Biosolutions

The Prime® Automated Liquid Handler unites powerful features for a fully integrated approach to lab automation. Collaborative 2-armed robot transport and dynamic tray loading and pipetting facilitate rapid and continuous pipetting, while vertical orientation saves on lab space. Pipetting heads, including 96 Multi-Channel, 384 Multi-Channel, and Independent Z-8 Channel are easily changed out on the fly.

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Cellario™ Whole Lab Automation Software

HighRes Biosolutions

Cellario™ Whole Lab Automation Software invigorates any automated workflow. This integration software framework brilliantly organizes, schedules, and runs multi-device workflows, and also manages device utilization and performance. Cellario seamlessly integrates with most laboratory information management systems (LIMS) or other internal software and enables scalable automation across a single lab or an expansive enterprise.

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Sample Storage Solutions

HighRes Biosolutions

Automated storage solutions from HighRes Biosolutions, including the SteriStore™ self-sterilizing automated incubator, AmbiStore™ random access ambient temperature sample storage carousel, and TundraStore™ automated low temperature freezer, protect sample integrity in standalone applications as well as when integrated into a fully walkaway Nucleus™ automation infrastructure.

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Automated Labware Management

HighRes Biosolutions

Automated labware management devices from HighRes Biosolutions, including those to deliver, orient, place, and dispose microplates and other consumables, offer consistently high performances whether they are used as a stand-alone devices in concert with a Prime® automated liquid handler or similar, or integrated into a fully walkaway Nucleus® automation infrastructure.

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Assay development and screening

Selvita

Selvita provides its clients with effective drug discovery support based on broad capabilities and deep expertise in small molecule drug discovery. The in vitro pharmacology support offering at Selvita covers drug discovery phases from target validation through to preclinical candidate selection. We provide a versatile protein-to-cell approach for the development of pharmacologically active compounds and biologics.

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ICPMS-2040/2050 Series

Shimadzu Corporation

The ICPMS-2040 Series and ICPMS-2050 Series inductively coupled plasma mass spectrometers (ICP-MS) provide approximately twice the sensitivity of conventional models through the use of a uniquely designed plasma torch (a mechanism to generate plasma). 

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PURASPIN®

FILTROX AG

PURASPIN ® depth filtration units are designed for small scale filtration trials. They allow efficient and cost-effective depth filtration of up to 20 mL. They can be used as a depth filter unit in a centrifuge or by applying vacuum.

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PURACAP® and PURACAP® BIO SD

FILTROX AG

PURACAP ® and PURACAP ® BIO SD are filter capsules for lab and pilot scale filtration trials. The capsules are used as a tool to generate the data needed for a propper scale-up. PURACAP ® is used for standard depth filtration (sheet filtration), PURACAP ® BIO SD for alluvial filtration (e.g. clarification of cell broth).

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ACTIVASORB® sheets, modules and caps

FILTROX AG

ACTIVASORB ® depth filter sheets are used in various applications such as decolorization, deodorization or catalyst removal. This type of filter sheets contains immobilized activated carbon which allows a easy and clean handling. In addtion, treatment with immobilized activated carbon is much more efficient compared to loose carbon powder due to a forced contact of the impurities with the activated carbon.

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PURASPIN® Test Kit

FILTROX AG

The PURASPIN ® Test Kit contains 5 different filter sheet types for laboratory filtration tests for coarse, fine, clarifying and sterile filtration. A practical and easy-to-use tool to define the right filtration solution at an early stage in the development process.

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Scale-up Test Kit

FILTROX AG

The SCALE-UP Test Kit is a tool to find the ideal depth filter at an early stage of the process development. The test kit contains 10 different PURASPIN ® for 20 mL trials, a 2" capsule with a selection of filter sheets for verification and the necessary information for a proper scale-up calculation.

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AAV Ratio Kit

Gator Bio

The Gator ® AAV Ratio Kit enables empty vs full determination of AAV serotypes 1-10 and chimeric serotypes in crude and purified samples. The AAV Ratio Kit includes: AAVX probes (96 probes/tray) SSB probes (96 probes/tray) Lysis Buffer DNA Detection Solution AAV Ratio Substrate Q Buffer SS DNA Standard Lysis tubes ** Contains temperature sensitive components. Must be shipped overnight. **

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In vivo pharmacology and toxicology

Selvita

Selvita’s in vivo team has long standing experience in the areas of infection, inflammation and fibrosis and has contributed to numerous  preclinical and clinical candidates.  Over 60 animal models in mice, rats, and rabbits are fully characterized and validated with clinically relevant pharmacological controls whereas in-depth expertise in translational biomarker selection and validation gives confidence in the smooth transi…

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RASTRUM™

Inventia

RASTRUM™ is a 3D cell culture platform that enables scientists to generate biologically and phenotypically relevant models for disease research, drug discovery, and translational applications with greater efficiency and consistency.

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