Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Single Cellome™ Unit SU10

Yokogawa Corp. of America

SU10 is a nanopipette-based tool for efficient and controlled delivery of material (such as CRISPR Cas9 complex, RNA, proteins) into the nucleus or cytoplasm of single cells in a highly automated manner. The CRISPR Cas9 complex can be delivered directly into the nucleus of a specific target cell in a minimally invasive manner through the utilized glass pipette in nanometer range (approx.100 nm).

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Phytocannabinoid Neutrals Mixture 8 (CRM)

Cayman Chemical Co.

Phytocannabinoid Mixture 8 (CRM) (Item No. 34043) is a certified reference material mixture that contains neutral, non-acid, forms of compounds that can be isolated from plants in the genus Cannabis.  Included are Δ9-THC, Δ8-THC, cannabinol, cannabidiol, (±)-cannabichromene, cannabidivarin, cannabigerol, and tetrahydrocannabivarin. It is provided as a DEA exempt preparation in an amber ampule in which the headspace has been p…

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Aura CL

Halo Labs

Aura® CL systems couples Fluorescent Membrane Microscopy and Backgrounded Membrane Imaging to help you understand what’s in your cell therapy. It detects, counts, sizes, and IDs cellular aggregates and subvisible particles and ID’s cellular from other particles without any machine learning so you can maximize the purity, safety, and efficacy of your therapeutic.

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Aura

Halo Labs

Aura® is the particle and aggregate detection system that combines Backgrounded Membrane Imaging which images 100% of your sample to give you count, size, and morphological information, with up to 2 channels of Fluorescence Membrane Microscopy. Identify if particles are protein or not with the first FMM channel and determine if your sample contains lipids, hydrophobic entities, or other aggregates of your choice with a second…

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CRISPRi Libraries, Pools, and gRNAs

Merck

Nuclease-independent applications of CRISPR provide equal targeting specificity but instead of cutting, CRISPRi allows for targeted interference of gene function by delivering transcriptional repressor domains to a specific target sequence using modified dCas9 + gRNA complexes. Gene knockdown is complementary to CRISPR-KO and CRISPRa (activation) and has distinct advantages over existing loss-of-function strategies like RNAi.…

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