Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
Reliable in vivo breath sample collection of VOCs and respiratory droplets for biomarker identification and validation. Suitable for use in a range of contexts and diverse applications including early detection, drug development and precision medicine for conditions including respiratory diseases, liver diseases and cancer. Compatible with a range of analytical systems including GC-MS analysis with Breath Biopsy Services.
Combining high resolution accurate mass mass spectrometry and world-leading breath analysis expertise to offer complete breath biomarker discovery and validation solutions. Breath Biopsy Services provide versatile Breath Biopsy sample analysis and reporting driven by GC-Orbitrap technology and supported by a rigorous quality assurance process ensuring reliable, high sensitivity VOC biomarker detection.
Exogenous volatile organic compound probes (EVOC Probes) enable targeted, non-invasive assessment of biological pathways. Probes are safe, easy to administer compounds that interact with characterised metabolic pathways with relevance to key disease areas. Using Breath Biopsy, EVOC Probes can be monitored non-invasively on breath, either alone or in parallel with biomarker discovery studies.
A targeted panel of compounds with established relevance for respiratory diseases enabling high confidence, non-invasive disease detection and monitoring. Each compound is supported by evidence from breath research studies of relevant respiratory diseases and disease processes. The panel is available as an aspect of Breath Biopsy Services and panels for other disease applications are in development.
Identify prospective biomarkers relevant to key disease processes through in vitro GC-MS analysis. Compatible with headspace sampling from cell cultures, macromolecular preparations and ex vivo samples. Driven by GC-Orbitrap high-resolution mass spectrometry and supported by a rigorous and comprehensive quality assurance process. Results are suitable for comparison with in vivo studies using Breath Biopsy Services.
Consumable components of the Breath Biopsy system, required for robust breath sample collection using the ReCIVA Breath Sampler as part of the Breath Biopsy Collection Station. One Kit per sample.
Reliable and reproducible, non-invasive Breath Biopsy sample collection for high-accuracy analysis of human breath. ReCIVA provides high quality sample collection alongside ease-of-use and patient safety and comfort. Samples are easy to store and transport and can be analysed using a wide range of techniques. We recommend processing Breath Biopsy samples using high-accuracy GC-MS, available through Breath Biopsy Services.
A versatile and easy to use analyzer for the detection of biomarkers in clinical samples using field asymmetric ion mobility spectrometry (FAIMS). Rapid, portable, sensitive and selective, Lonestar has wide-ranging applications for the detection and quantification of volatile organic compounds (VOCs) from a variety of sample types including feces, urine and breath.
Easy setup directly on your microscope: perform live cell imaging in dishes, slides, or multiwell plates. The ibidi Stage Top Incubation Systems fit every standard inverted microscope and include CO 2 and O 2 control as well as actively controlled humidity. They are ideal for all live cell imaging applications and available for single slides and dishes as well as for multiwell plates.
Use this versatile 35 mm imaging Dish for high-end microscopy through the #1.5 coverslip bottom.
Use this high-quality rat tail collagen type I solution for cell culture applications (e.g., 3D gels, scaffolds, and coating).
Use this Multiwell plate with black walls, square wells, and a flat and clear coverslip bottom (#1.5 ibidi Polymer Coverslip) for high-throughput applications in cell-based assays. Also available with 24 wells.
Use this channel microscopy slide with a coverslip bottom (#1.5 ibidi Polymer or #1.5H glass) for immunofluorescence, cell culture under flow, live cell imaging, and high resolution microscopy on inverted microscopes. Available in various channel heights.
Use these silicone inserts with a defined cell-free gap for wound healing assays, migration assays, 2D invasion assays, and co-cultivation of cells. Available with 2, 3, or 4 wells.
Use this slide to investigate angiogenesis in tube formation assays. Also ideal for 3D cell culture and immunofluorescence staining. Also available in a 96 well format.
Investigate chemotaxis of fast or slow migrating adherent cells and non-adherent cells in 2D or 3D gel matrices.
The SOLATION® Inductively Coupled Plasma Mass Spectrometer (ICP-MS) – the ultimate instrument for multi-element analysis, the SOLATION® provides high sensitivity measurement of trace elements from a wide range of matrices including complex samples such as urine, serum, plasma, whole blood and tissue, water, soil, food, beverage and agricultural samples.
Phytocannabinoid Mixture 11 (CRM) (1 ml, 250 µg/ml) (Item No. 21306) is a certified reference material mixture provided as a DEA exempt preparation. Included are Δ9-THC, Δ8-THC, tetrahydrocannabinolic acid A, cannabinol, cannabidiol, cannabidiolic acid, (±)-cannabichromene, cannabigerol, cannabigerolic acid, cannabidivarin, and tetrahydrocannabivarin. It is supplied in an amber ampule in which the headspace has been purged w…
Phytocannabinoid mixture 10 (CRM) (Item No. 21305) is a certified reference material mixture containing tetrahydrocannabinols, which are regulated as Schedule I compounds in the US. Included are Δ9-THC, Δ8-THC, tetrahydrocannabinolic acid A, cannabinol, cannabidiol, cannabidiolic acid, (±)-cannabichromene, cannabigerol, cannabigerolic acid, and cannabidivarin. It is supplied in an amber ampule in which the headspace has been…
Phytocannabinoid Mixture 6 (CRM) (Item No. 25077) is a certified reference material mixture provided as a DEA exempt preparation. Included are Δ9-THC, THCA-A, cannabidiol, cannabidiolic acid, cannabinol, and cannabigerol. The mixture is supplied in an amber ampule in which the headspace has been purged with argon.
Phytocannabinoid Mixture 5 (CRM) (Item No. 25076) is a certified reference material mixture provided as a DEA exempt preparation. Included are Δ9-THC, THCA-A, cannabidiol, cannabidiolic acid, and cannabinol. The mixture is supplied in an amber ampule in which the headspace has been purged with argon.
Mycotoxin Mixture 5 (CRM) (Item No. 28151) is a certified reference material secondary standard mixture that contains mycotoxins produced by fungi that have been found in Cannabis samples and cultivation materials. Included are aflatoxin B1, B2, G1, G2, and ochratoxin A. The mixture is supplied in an amber ampule in which the headspace has been purged with argon.
THCA-A (CRM) (Item No. ISO60175) is a certified reference material that is structurally categorized as a cannabinoid. THCA-A is a phytocannabinoid that is a common component of hashish. There are two acid isomers of Δ9-THC, THCA-A and THCA-B. In THCA-A, the carboxylic acid group is found at the 2 position. Neither THCA-A nor THCA-B is psychoactive, although both forms are decarboxylated upon heating to form the active Δ9-THC.…
Tetrahydrocannabivarinic acid (CRM) (Item No. 21259) is a certified reference material categorized as a phytocannabinoid. Tetrahydrocannabivarinic acid has been found in strains of Cannabis and is a precursor in the biosynthesis of tetrahydrocannabivarin. Tetrahydrocannabivarinic acid (CRM) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.
One Step WGA Kit for Whole Genome Amplification with BIORONs unique SD Polymerase
