Drug discovery > Target Discovery Products & Reviews

Fibroblast growth factor-acidic

Interleukin 1 beta, animal component-free

Antibiotic; mTOR pathway inhibitor; Inhibits FKBP-12

MEK/ERK pathway inhibitor; Inhibits MEK1 and MEK2

Activin/Nodal/TGFß pathway inhibitor; Inhibits ALK5

Activin/BMP/TGF-ß pathway inhibitor; Inhibits ALK5

Antioxidant; COX-1 inhibitor

Adenosine receptor, non-muscle myosin II (NM II), MEK1, and aurora kinase inhibitor

Epigenetic modifier; Inhibits DNA methyltransferase (DNMT)

RHO/ROCK pathway inhibitor; Inhibits ROCK2

cAMP pathway activator; Inhibits type 4 cyclic nucleotide phosphodiesterases (PDE4)

PPAR? activator

HDR pathway enhancer; Enhances RAD51

Epigenetic modifier; Inhibits DNA methyltransferase (DNMT)

JAK/STAT pathway inhibitor; Inhibits JAK1 and JAK2

Hedgehog pathway activator; Activates Smoothened (SMO)

Epigenetic modifier; Inhibits HDAC1 and HDAC3

p38 MAPK inhibitor

p38 MAPK inhibitor

WNT pathway activator; Inhibits GSK3a and GSK3ß

Activin/BMP/TGF-ß pathway inhibitor; Inhibits ALK4, ALK5, and ALK7

NHEJ pathway inhibitor; inhibits DNA ligase IV

Inducer of cardiac differentiation

Epigenetic modifier; Inhibits DNA methyltransferases (DNMTs)

Anti-inflammatory