Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Prep 96 Homogenizer

OMNI International Inc.

The unique Omni Prep96 Multi-Sample Homogenizer supports automated homogenization of up to ninety six samples in a single batch in sample tubes ranging from 1.5 mL to 50 mL. With the Omni Prep96 workflow software, custom profiles can be created and deployed in minutes through an interactive GUI for hands-free sample prep of one to ninety six samples. Human Like Generator Probe Movement The Omni Prep 96 was designed to provide…

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UltraFAIMS

Owlstone Medical

Enhance existing mass spectrometry pipelines by integrating in-source field asymmetric ion mobility spectrometry (FAIMS) ino separation capabilities. ultraFAIMS adds orthogonal separation capacity to existing chromatography/mass spectrometry systems enabling enhanced compound detection and quantification.

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Maybridge Screening Collection

Thermo Fisher Scientific

The Maybridge Screening collection consists of over 53,000 organic compounds, largely produced by us at Maybridge. These are individually designed compounds, produced by innovative synthetic techniques, based on over 45 years of experience in heterocyclic chemistry. The pre-plated HitFinder™ Collection consists of 14,400 Maybridge Screening Compounds, selected to represent the diversity of the Maybridge Screening Collection u…

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High Resolution ChIP-seq Library Prep kit

Diagenode

Diagenode's High Resolution Library Preparation Kit significantly enhances the resolution of transcription factor binding sites to single nucleotide levels.Using an optimized, proprietary protocol using an exonuclease to digest protein-bound DNA from the 5' end to within a few nucleotides of the protein binding site, the precise location of transcription factor-bound DNA can be determined. The High Resolution Library Preparati…

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ACSIA NGSLibPrep Edition

PrimaDiag

ACSIA NGSLibPrep Edition, the solution to automate the libraries preparation for next-generation sequencing. In view of increasing your productivity, avoiding contamination and improving your work efficiency, PrimaDiag created ACSIA NGSLibPrep Edition. It uses our software PrimaControlleur®II and has been designed to allow you to effectively perform your libraries preparation.ACSIA NGSLibPrep Edition allows you to perform 96…

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iDeal Library Preparation Kit

Diagenode

The iDeal Library Preparation Kit reliably converts DNA into indexed libraries for next-generation sequencing, with input amounts down to 5 ng.Our kit offers a simple and fast workflow, high yields, and ready-to-sequence DNA on the Illumina platform. Combine this kit with our iDeal ChIP-seq kit for optimal ChIP-seq results. For library preparation of DNA inputs down to 50 pg, our MicroPlex Library Preparation Kit is an optimal…

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Mapix

Innopsys

Simple, User-friendly, High performance. Mapix is a data acquisition and analysis software for microarray images which combines ease-of-use, user-friendliness and high performance. Mapix has the most up to date requirements to browse data from microarray experiments quickly with a high level of reliability and optimised productivity. Mapix is available for 32 and 64 bit operating systems (Windows, Linux and soon MacOS).…

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MicroLiter Chromatography / Autosampler Vials

WHEATON

MicroLiter was founded in 1996 to supply autosampler vials and consumables for the industry’s leading autosamplers. In 2012, MicroLiter became part of the WHEATON family of products.Since inception, MicroLiter has made the fundamental decision to only offer products that offered proven stable performance and to avoid those products that had a wide range of tolerances which could impede the performance of the autosampler.In add…

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Sepmag Q

Sepmag

For homogeneous and Large Volume separations. Production departments need an efficient and economical process to use batches of several liters, with throughputs high enough to meet demand and avoiding particle losses. Sepmag Q is a biomagnetic separation technology specifically developed to process large batch volumes in nucleic acid separation, protein purification, cell isolation, biocatalysts, therapeutics and diagnostics.…

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iMScope TRIO

Imaging Mass Spectrometry identifies what you see at the molecular level iMScope TRIO transforms your data from just "Observation" to "Analysis". The instrument is a combination of an optical microscope which allows the observation of high-resolution morphological images, with a mass spectrometer which identifies and visualizes the distribution of specific molecules. Superimposing the two images obtained based on these very d…

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FAM FLICA® Caspase 1 Assay Kit

Immunochemistry Technologies LLC

Detect caspase-1 activity with the FLICA® Caspase 1 Assay Kit. This in vitro assay employs the green fluorescent inhibitor probe FAM-YVAD-FMK to label active caspase 1 enzyme in living cells or tissue samples. Analyze the fluorescent signal using fluorescence microscopy, a fluorescent plate reader, or by flow cytometry. Caspase 1 (ICE):Members of the mammalian caspase family of cysteinyl aspartate-specific proteases play disti…

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Magic Red™ Caspase 3 & 7 Assay Kit

Immunochemistry Technologies LLC

Magic Red™ Caspase 3 and 7 Assay is a substrate-based fluorescent apoptosis assay that measures DEVDase enzyme activity in living, intact cells. Detection of caspase 3 and 7 activity (DEVDase enzymes) is a reliable method for assessing apoptotic activity in experimental cell populations. The Magic Red™ caspase 3 and 7 fluorogenic substrate, MR-(DEVD)2, is primarily targeted by caspases 3 and 7 of the apoptotic protease casca…

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RetroNectin® Reagent

Takara Bio

Research and Clinical Grade RetroNectin Reagent for Retroviral or Lentiviral Transduction. RetroNectin Reagent for retroviral or lentiviral transduction significantly increases transduction efficiency and results in enhanced gene transfer, especially in suspension and hematopoietic stem cells. RetroNectin Reagent is a chimeric peptide composed of E. coli-derived recombinant human fibronectin fragment that contains three funct…

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Mouse ROSA26 safe harbor gene knock-in kit and clones

GeneCopoeia

Mouse ROSA26 safe harbor gene knock-in kit and clones. ROSA26 (also known as ROSAβgeo26 locus) in mice genome is first found in chromosome 6 in one particular strain of mice-named ROSAβgeo26-expressed β galactosidase from a randomly inserted transgene at high levels uniformly in nearly all tissues examined. This locus expresses one coding transcript and two noncoding transcripts, and only the non-coding transcripts are disrup…

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PureFlex™ process container film

Merck KGaA, Darmstadt, Germany

Designed to provide strength, flexibility (with maximum resistance to flex-crack), excellent gas barrier performance and inert contact. PureFlex™ Single-use process container films are flexible, robust and chemical resistant materials used in the construction of our single-use process containers, including Mobius® assemblies and NovaSeptum® sterile sampling products.PureFlex film is a high purity, medical grade, coextruded fi…

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CRISPR-Cas9 Custom Services

GeneCopoeia

GeneCopoeia offers complete custom services for CRISPR-Cas9-based targeted genomic modification, including CRISPR design and construction, donor design and construction, functional validations, stable cell line establishment, and transgenic mouse generation. Service Details: Validation Services Donor clone services Stable cell line services Transgenic mouse services Advantages: Fast delivery of CRISPR-Cas9 plasmids…

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MWave 5000 Microwave Synthesis System

Buck Scientific, Inc.

The MWave-5000 multifunctional microwave is truly a robust system. The 5000 Integrates microwave synthesis, distillation,concentration, pressurized or non-pressurized reaction, and low temperature microwave reaction into one system. Features: The 5000 has three modes of reaction, under pressure, Normal pressure, and decompressed. Three different sample vessel volumes 300ml, 500ml, and 1 Liter. Variable magnetron outp…

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ChIPettor™ System

Diagenode

The ChIPettor™ System has everything you need for high-quality, fast, and easy chromatin immunoprecipitation for either histones or transcription factor ChIP. Contains a full set of reagents for start-to-finish ChIP starting with 100,000 to 1,000,000 cells (ideal for histone pull down), purification reagents, and a semi-automated pipettor with special resin pipet tips. The ChIPettor™ is designed to stand independently on a 9…

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SMART cDNA Synthesis Kits

Takara Bio

SMART (Switching Mechanism at 5’ End of RNA Template) is a unique technology that allows the efficient incorporation of known sequences at both ends of cDNA during first strand synthesis, without adaptor ligation. The presence of these known sequences is crucial for a number of downstream applications including amplification, RACE, and library construction. While a wide variety of technologies can be employed to take advantag…

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PluraScan 2D Bar Code Reader

WHEATON

Features: Works with WHEATON KeepIT 81 & 100 Boxes and WHEATON CryoELITE Cryogenic Vials and Cryule Ampules Integrated frost reduction system allows multiple racks to be read Flexible software integration Capable of reading bar codes from wide range of manufacturers and label printers Conformance to CE standards 1 year warranty

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Magnetic Work Unit

PrimaDiag

Module for handling of magnetic beads combining simplicity and efficiency. This innovative module allows replacing the common gripping systems thanks to its patented technology APIM (Attraction Point by Induced Magnetization). Moreover it is provided with a retaining flange allowing using directly your microplates twisted by the heat of the thermal cycler and avoiding any move.The main goal is to focus the magnetic field gene…

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