Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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TNT® Quick Coupled Transcription/Translation System

Promega Corp.

The TnT® Quick Systems are convenient single-tube, coupled transcription/translation reactions for eukaryotic cell-free protein expression.   These cell-free expression systems combine the RNA Polymerase, nucleotides, salts, amino acids and Recombinant RNasin® Ribonuclease Inhibitor with the reticulocyte lysate solution to form a single TnT® Quick Master Mix. The TnT® Quick Coupled Transcription/Translation System is ava…

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ORF Clones

Promega Corp.

The Kazusa ORFeome Project was initiated to create a collection of human and mouse ORFs to enable the larger research community with a readily accessible, highly validated ORFeome. Kazusa DNA Research Institute (KDRI) is an academic Japanese research institute dedicated to genome-scale studies and the function of individual genes. KDRI is an active member of the global ORFeome Collaboration, and are experts in HUGE (Human Uni…

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Single Step (KRX) Competent Cells

Promega Corp.

The Single Step (KRX) Competent Cells are designed for efficient transformation and tightly controlled protein expression.   These cells consolidate the best attributes of these two steps into one strain to evaluate protein expression in E. coli. Transformation efficiencies are greater than 108 cfu/μg, similar to other highly competent cells. The single step cells are available in single transformation size (50μl). KRX a…

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Competent Cells

Promega Corp.

For standard cloning experiments competent cells are available in two formats: high efficiency at greater than 108cfu/μg for cloning (JM109, HB101), and subcloning efficiency at greater than 107cfu/μg (HB101). JM109 cells have the additional feature of blue/white screening for recombinants. For protein expression, JM109(DE3), BL21(DE3) or KRX competent cells can be used. The Single Step (KRX) Competent Cells are designed fo…

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Cell Line Authentication

Promega Corp.

Promega has partnered with ATCC to offer unparalleled STR testing service for human cell line authentication.   This service provides easy access to proven and comprehensive validation techniques. Promega's proprietary PowerPlex® and GenePrint® STR technology coupled with ATCC's considerable experience profiling human cell lines and extensive internal assets around STR profiling data interpretation is particularly r…

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SuperCool 75 Condenser

Genevac

The demand for a more powerful and colder condenser has naturally arisen as the boundaries of evaporation science are pushed further and further. Users increasingly regard as critical the importance of having the right condenser for the job, with the correct power and temperature profile matched to the characteristics of the evaporator. Genevac has developed the super-powerful and super-cold SuperCool 75, in collaboration wit…

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Solid Phase Extraction Products (SPE cartridges & Well Plates) – SiliaPrep™ & SiliaPrepX™

SiliCycle Inc.

Solid Phase Extraction (SPE) is the basis of analytical laboratories. A crucial step of this process is sample preparation. Therefore we know that a clean sample will yield better results. To achieve this goal SiliCycle has designed SiliaPrep, which is a silica based sorbent exempt of fines, and SiliaPrepX, polymeric based sorbent, that can be found in cartridges, well plates and SPME (Solid Phase Micro-Extraction) cartridges…

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The MiniBlock - SiliCycle

SiliCycle Inc.

The MiniBlock® is an easy-to-use reaction block designed for parallel synthesis and screening. Its unique valve body design enables processes where filtration is critical, including solid-phase organic synthesis, use of scavenger resins with solution phase synthesis and parallel purification via Solid-Phase Extraction (SPE).Make the choice many chemists have made to increase productivity, more so than any other similar tool.…

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QuantiFluor® ONE dsDNA System

Promega Corp.

QuantiFluor® ONE system maximizes sensitivity and efficiency for dsDNA quantitation.   The QuantiFluor® ONE dsDNA System contains a fluorescent double-stranded DNA-binding dye (504nmEx/531nmEm) developed for use in an “add-and-read” format for dye and standard, making sample quantitation easy. This system enables sensitive quantitation of small amounts of double-stranded DNA (dsDNA). The QuantiFluor® ONE dsDNA Sy…

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TransIT®-Insect Transfection Reagent

Mirus Bio LLC

High yield transient transfection and baculovirus titers in insect cells. Insect cell expression is a platform used to produce proteins with simple post-translational modifications. Transient transfection and recombinant baculovirus production are commonly used methods for insect cell expression.TransIT®-Insect Transfection Reagent is an animal-origin free transfection reagent specifically optimized for high gene expression i…

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eGecko

Kbiosystems

kbiosystems barcode application automated systems offer the ideal solution to high throughput to the single application of barcode labels to plates racks and Petri dishes. The new, smaller barcode application automated system offers the ideal solution to high throughput to single application of barcode labels to SBS plates and Petri dishes.The eGecko utilises robust and proven custom designed label printer in association with…

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Washer/Dispenser II

GNF Systems

The GNF Systems WDII is designed for uncompromising plate washing performance in a liquid handling device. It performs the most demanding tasks with ease, including fast, accurate, precise reagent dispensing and gentle liquid aspiration that are all user tunable. Combined, this functionality minimizes cell disruption and empowers you to perform sophisticated assays & screens not possible with other plate washers.This device i…

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Sample Preparation Devices

HORIBA Scientific

WIN IN EFFICIENCY, AUTOMATION, SPEED & SAFETY WITH OUR NEW SAMPLE PREPARATION DEVICES HORIBA Scientific offers a great range of possible solutions for our analyzers, to save time and ensure that the end results are as accurate as possible! Whatever your analytical solutions: ICP-OES, ICP-MS, AA, Fluorescence X, elemental analyzers, etc.… HORIBA Scientific can provide you with many sample preparation devices, such as: • Grinder…

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ProteinCenter™ Data Interpretation Software

Thermo Fisher Scientific

ProteinCenter™ is a web-based data interpretation tool that enables scientists to compare and interpret data sets in minutes instead of months ProteinCenter is a web-based tool that enables scientists to compare and interpret proteomics data sets in minutes and overcomes the hurdle of proteins existing under different names and accession keys in different databases. Regularly updated from all major protein databases, ProteinC…

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eViper Plate Handling System

Kbiosystems

Kbiosystems Plate Handling Series of automated and semi automated systems offer ideal entry level automation laboratories require for a reliable, consistent plate and tube handling The Viper is a combined feeding system to either left and right hand sides, the plate is handled in portrait or landscape format and allowing the use of non lid and lidded plates.Offering complete versatility, the Viper will work with a wide range…

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SeqCap Epi System

The SeqCap Epi Enrichment System is a set of target enrichment tools for DNA methylation assessment at single-base resolution. SeqCap Epi Kits are available in a variety of product offerings. Depending on your organism of choice and genomic region of interest, there are products cover your needs. Applying concepts similar to those demonstrated by the best-in-class technical performance of the SeqCap EZ products, Roche NimbleG…

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Genefficiency™ Targeted Sequencing Services

Oxford Gene Technology Ltd

OGT can help you get straight to the variant of interest with whole exome or custom targeted sequencing services. Genefficiency™ targeted sequencing services are designed to be different, leading you all the way from project conception to high-quality results. Our expert and comprehensive project design and analysis solutions — incorporating Agilent SureSelect, Illumina HiSeq 2000 and OGT-developed software platforms — are ta…

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Genefficiency™ RNA-Seq Service

Oxford Gene Technology Ltd

A high-quality RNA sequencing service designed to deliver cost-effective and rapid access to meaningful transcriptomics results. The Genefficiency™ RNA-Seq Service from OGT provides a new level of assay customisation to ensure each experiment is fully optimised to suit your specific study objectives. At OGT we understand the time and effort it takes to generate good quality RNA and how precious your samples are. Whether you a…

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The Phoenix Liquid Handling System

Art Robbins Instruments

The Phoenix is a multi position, high-throughput liquid-handling platform used around the world that incorporates a space-saving design with flexible dispensing options. The competitively priced Phoenix provides increased efficiency and cost-effectiveness. It is designed to meet the demanding requirements of protein crystallography, high throughput screening and genomics laboratories. This unique instrument combines the preci…

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Bio-Plex Pro™ RBM Apoptosis Panel 1

Bio-Rad

1 x 96-well, includes magnetic capture beads, detection antibodies, standards, controls, standard diluent, buffers, streptavidin-PE, flat bottom plate, plate seals, for the detection of 4 apoptosis markers in cell and tissue lysates

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Bio-Plex Pro™ RBM Apoptosis Panel 2

Bio-Rad

1 x 96-well, includes magnetic capture beads, detection antibodies, standards, controls, standard diluent, buffers, streptavidin-PE, flat bottom plate, plate seals, for the detection of 5 apoptosis markers in cell and tissue lysates

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Bio-Plex Pro™ RBM Apoptosis Panel 3

Bio-Rad

1 x 96-well, includes magnetic capture beads, detection antibodies, standards, controls, standard dilluent, buffers, streptavidin-PE, flat bottom plate, plate seals, for the detection of 4 apoptosis markers in cell and tissue lysates

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Camargo Preclinical Service

Camargo ensures the appropriate regulatory requirements are met every step of the way, streamlining your drug development process all the way to approval.Ready to guide you through the preclinical stage of drug development, Camargo provides strategic support in the following areas: CRO selection Study design Study setup and execution Project management In clinical program development, camargo's focus is unwavering:…

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HT4000A Sample Prep Workstation

HTA s.r.l.

HT4000A is a sample preparation workstation that allows automation of sample preparation procedures by taking care of a large number of operations such as liquid handling, purification or filtration (including Solid Phase Extraction (SPE), Micro Extraction by Packed Sorbent (MEPS), Whatman® Mini-UniPrep® syringeless vials, syringe-filters and liquid/liquid extraction (LLE)), tracking and further sample processing such as vorte…

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