Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Fluorokine® Multianalyte Profiling (MAP) Kits

Bio-Techne

Fluorokine MAP Kits for the Luminex platform are highly efficient multiplex assays that have been validated for the quantification of factors in complex matrices and require little or no optimization. For a wider selection of analytes, please see our VersaMAP™ line of development kits validated for use with cell culture supernatants. Features Simultaneously detect multiple analytes Requires small sample volume (Undergoes simil…

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VersaMAP™ Magnetic Custom Multiplex Kits

Bio-Techne

The VersaMAP™ Magnetic Custom Multiplex Kits are our most efficient Luminex-based multiplex assays. These homogeneous, no wash assays utilize analyte-specific antibodies conjugated to superparamagnetic microparticles to simultaneously detect up to 25 user-defined phosphorylated receptor tyrosine kinases (RTKs) in a single sample. Available Kits VersaMAP Magnetic Human RTK Kit A VersaMAP Magnetic Human RTK Kit B Features • Comp…

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PGN003 PureGenome™ Next Generation Sequencing Library Amplifier

Merck

The PureGenome™ High Efficiency Next Generation Sequencing (NGS) Library Preparation Reagents are uniquely optimized as a one-stop solution for NGS Library Preparation. Validated for sequencing compatibility with Illumina® instruments; three sets of reagents are offered each having a unique functionality in the library preparation work flow. The PureGenome NGS Library DNA Modifier, when purchased with the PureGenome NGS Librar…

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PGN002 PureGenome™ Next Generation Sequencing Library A-Tail Enhancer

Merck

The PureGenome™ High Efficiency Next Generation Sequencing (NGS) Library Preparation Reagents are uniquely optimized as a one-stop solution for NGS Library Preparation. Validated for sequencing compatibility with Illumina® instruments; three sets of reagents are offered each having a unique functionality in the library preparation work flow. The PureGenome NGS Library DNA Modifier, when purchased with the PureGenome NGS Librar…

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PGN001 PureGenome™ Next Generation Sequencing Library DNA Modifier

Merck

The PureGenome™ High Efficiency Next Generation Sequencing (NGS) Library Preparation Reagents are uniquely optimized as a one-stop solution for NGS Library Preparation. Validated for sequencing compatibility with Illumina® instruments; three sets of reagents are offered each having a unique functionality in the library preparation work flow. The PureGenome NGS Library DNA Modifier, when purchased with the PureGenome NGS Librar…

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PGN004 PureGenome™ Next Generation Sequencing Library Validator Kit

Merck

The quality of sequence obtained from Next Generation sequencing platforms such as Illumina, Inc. requires the accurate determination of input library DNA. Loading too much DNA can lead to overlapping clusters and loss of read counts whereas too little input can lead to poor read lengths and lower sequence output. The PureGenome™ NGS Library Validator Kit measures the absolute amount of adapter-ligated, sequence ready DNA in I…

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NovaSeptum Sampling System

Merck

A sterile, closed, disposable system for sampling fluids from sterile and aseptic processes The unique NovaSeptum sampling system is ideal for general fluid and cell culture sampling from aseptic and sterile processes. Both systems can be configured for high purity or autoclavable sampling applications and as single or multiple sampling units. A wide range of holders and connectors are also available. •  Closed sampling elimin…

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OneTRAC™ combined service

Plexpress

OneTRAC™ allows you to profile every gene, validate biomarker signatures, and apply your findings across all your studies. One-stop service for all your gene expression profiling needs All-inclusive gene expression data for pattern recognition and pathway analyses at the macro- and micro-levels Streamlined and integrated methodology from screening to validation of gene signatures Cost-efficient expression profiling f…

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Vena8 Fluoro+ Biochip: microfluidic flow chamber

Cellix Ltd

The Vena8 Fluoro+™ biochip is ideal for studying cell receptor-ligand interaction and is compatible with confocal microscopy. As cells flow through the microcapillary of the Vena8 Fluoro+™ biochip, the cell surface receptors may interact with adhesion molecules or ligands which coat the microcapillary walls. Ideal for use with fluorescence immunostaining, confocal microscopy and for applications such as thrombosis.

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Vena8 Endothelial+ Biochip: microfluidic flow chamber

Cellix Ltd

The Vena8 Endothelial+™ biochip is ideal for studying cell-cell interaction. Endothelial cells are easily seeded (via standard pipette) and cultured inside the microcapillaries of the biochip. As cells flow through the microcapillary of the Vena8 Endothelial+™ biochip, the cell surface receptors may interact with the endothelial cell monolayer which coats the microcapillary walls. Ideal for use with phase contrast imaging an…

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Micro Array Slide Spinner

Eurotech

Prior to scanning a micro array slide, it is necessary to remove all wash buffer. This drying step is critical to obtain the best possible scanning results. The Slide Spinner dries 2 micro array slides within a 10 seconds - simply insert your slides into the cassettes and close the lid! The Slide Spinner quickly accelerates to 4800 RPM, the optimal speed for quick drying without any splashing. Open the lid and the rotor comes…

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HistoChoice MB

NBS Biologicals Ltd.

Safer alternative to formalin-based fixatives, contains no formaldehyde, mercury or gluteraldehyde, tissue retains a more natural look and feel enabling easier, smoother cutting and sectioning, no cross linking of tissues as experienced with formalin-based fixatives.

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K Series Cryostorage Systems

Taylor-Wharton

The K Series Cryogenic Systems provide reliable liquid nitrogen storage with controllable temperatures between -100ºC and -196ºC. The added safety of automatic filling, alarms, easy access to stored product, and the unique Temperature Gradient Suppression System significantly improves vapor phase storage temperature and recovery. K Series Cryogenic Systems Features: Temperature control standard Temperature monitor stan…

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DYMENSION 1

Syngene

Revolutionary 2DGE Software Analysis of single 2D gels - Dymension 1 is ideal for users looking for software to analyse spots between samples containing one 2D gel only. It offers a range of automatic image correction features and methods for resolving and analysing spots on single gels. The software can be easily upgraded to Dymension 2 or 3 if the proteomics needs of the laboratory change.

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SOD Assay Kit - WST

NBS Biologicals Ltd.

SOD or SOD-like activity detection.  WST-1 based SOD inhibition assay, colourimetric microplate measurement, measures 100% inhibition by SOD, pH-independent IC50 determination, low background noise measurement.

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Spectra/Por Float-A-Lyser

NBS Biologicals Ltd.

Ready-to-use dialysis device with a broad built-in range of precise MWCO's and all the needed accessory components built in for ultimate convenience.  Features leak proof and re-sealable snap-on cap for sampling, colour coded dot for MWCO, broad floatation disk for buoyancy, 6 volume-specific size, 2 membrane types- biotech grade regenerated cellulose (RC) and biotech grade cellulose ester (CE).

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GeneJuice® Transfection Reagent

Merck

GeneJuice® Transfection Reagent is a proprietary formulation optimized for maximal transfection efficiency, ease of use, and minimal cytotoxicity. This transfection reagent is a superior alternative to a wide variety of other techniques including calcium phosphate coprecipitation, electroporation, microinjection, biolistic particle delivery, and complex formation with DEAE-dextran. Whereas many available transfection reagents…

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BugBuster® Master Mix

Merck

BugBuster® Master Mix combines BugBuster Protein Extraction Reagent with Benzonase® Nuclease and rLysozyme™ Solution in one convenient reagent. BugBuster Master Mix allows for maximum recovery of active soluble protein from both Gram-negative and Gram-positive bacteria. With the Master Mix, there is no need for dilution or separate addition steps. The two available package sizes provide sufficient reagents for protein extracti…

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ProteoExtract® Subcellular Proteome Extraction Kit

Merck

AVOID FREEZE/THAW CYCLES. The ProteoExtract Subcellular Proteome Extraction Kit is a tool for the differential extraction of proteins from adherent or suspension tissue culture cells according to their subcellular localization. The sequential extraction steps yield fractions containing cytosolic proteins, plasma membrane and organelle proteins, soluble nuclear proteins, and finally cytoskeletal and nuclear matrix proteins. To…

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