Drug discovery > Target Discovery Products & Reviews

Sensitive Quantitation of Single-Stranded DNARequires less DNA than spectrophotometry

Directly Measure HDAC-Test Compound Affinity and Residence Time in Live Cells

BRET-Based Assays to Detect Protein:Protein Interactions in Live Cells

LDH-Glo™ Cytotoxicity Assay detects cell death from a small number of cells, including 3D cell cultures, based on the release of lactate dehydrogenase.

The RealTime-Glo™ Annexin V Apoptosis and Necrosis Assay provides a no-wash, one-step Annexin V assay that allows continual monitoring of cell state to determine apoptotic onset using a plate-reading luminometer.

The GSH/GSSG-Glo™ Assay is a bioluminescent assay to detect and quantitate total glutathione ratios.

The Caspase-Glo ® 1 Inflammasome Assay  directly measures inflammasome activation with a simple add-mix-measure protocol.

Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism of action of antibodies through which virus-infected or other diseased cells are targeted for destruntion by components of the cell-mediated.

The TNT® Coupled Reticulocyte Lysate Systems offer researchers an alternative for eukaryotic cell-free protein expression: a single-tube, coupled transcription/translation system. The TNT® Lysate Systems greatly simplify the process and reduce the time required to obtain in vitro translation results.

ProteaseMax™ Surfactant is a high-quality reagent for use in protein and peptide sample preparation.   ProteaseMax™ Surfactant solubilizes proteins and ensures fast and improved protein digestion with trypsin or chymotrypsin. It is designed to degrade over the course of a digestion reaction, yielding products that are compatible with downstream methods such as mass spectrometry (MS) and liquid chromatography (LC). For…

HaloLink - Promega Magnetic Beads for Covalent immobilization of HaloTag® fusion proteins.   Features of the Promega HaloLink Magnetic Beads: • Magnetic-Based: Easy and quick immobilization of HaloTag® fusion proteins with minimal loss of sample material. • Covalent Bond: Allows stringent washing of immobilized HaloTag® fusion protein, removing nonspecific proteins and enhancing overall data.  • Multiple Appli…

Predesigned probe assays for gene expression analysis

Modulation of gene expression with modified oligos

Proteinase K from Tritirachium album ELEVATE  

Proteinase K from Tritirachium album ELEVATE

Save space, Protect Samples.

Multiplate live-cell analysis system

The Vision G2 Classic 6 dissolution tester is a compact, rugged workhorse, precision engineered to ease the rigors of a manual dissolution test.

The Vision G2 Elite 8 dissolution tester is a versatile performance machine, built with the highest quality components and engineering for automated dissolution testing.

The Vision AutoPlus offers precision pump mechanics, all-inert syringes, valves, tubing, and fluidics, and a choice of 6 or 8 sampling channels in DissoScan™ (single-bath) or Maximizer™ (multi-bath) configurations.

The CD14 Comparative Dissolution allows testing of two different drugs at once. Hanson’s Super Precision Vessel™ provides more consistent vessel-to-vessel dissolution test results in USP Apparatus 2.

The CD AutoPlus is designed for plug-and-play operation with 14-vessel CD14 Comparative Dissolution Testers. With 10 mL syringes and a volume accuracy of ± 1%, the CD AutoPlus easily accommodates sampling intervals under 5 minutes.

Fully automated sampling, collection, and media replace with the ability to run up to 24 cells at once from a single computer workstation

Six-cell manual sampling in a compact footprint with an advanced touch screen display

Made from precision borosilicate glass, with mixer inserts engineered to produce instant homogenization of receptor media