Unlock immune insights with Crown Bioscience’s high-throughput flow cytometry—precisely characterize immune cell populations across tissues to elucidate drug mechanisms, assess pharmacodynamics, and optimize immunotherapies.
Pion’s PAMPA high-throughput permeability assay uses a range of membranes to mimic physiologic conditions. It allows you to evaluate the passive permeability of API’s as well as the absorption potential of simple or complex formulations using robust models and protocols in a 96-well format.
Accelerate the development of your immuno-oncology drugs with Crown Bioscience’s large panel of immunocompetent syngeneic models.
Crown Bioscience’s preclinical biomarker services help identify, validate, and analyze biomarkers across diverse in vitro and in vivo cancer models. Using multi-omics platforms and expert bioinformatics, these services support drug mechanism studies, patient stratification, and companion diagnostic development to guide oncology drug discovery.
Human TNF-alpha Protein, His Tag (TNA-H5228) is expressed from human 293 cells (HEK293). It carries a polyhistidine tag at the C-terminus, and has a calculated MW of 18.3 kDa. The protein migrates as 17-19 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Biotinylated Human VEGF165, His,Avitag(VE5-H82Q0) is expressed from human 293 cells (HEK293). It carries a polyhistidine tag at the N-terminus, followed by an Avi tag (Avitag™), and has a calculated MW of 22.4 kDa (monomer). The protein migrates as 25-33 kDa (monomer) under reducing (R) condition, and 42-55 kDa (homodimer) under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Simplify your workflow and save valuable laboratory time with the fully automated MACS® Sampler, a perfect extension for the MACS® Matchmaker instrument, allowing you to fully integrate automatization solution for your interaction studies.
KREX™ i-Ome™ Discovery Services enable highly multiplexed autoantibody profiling for rapid, reproducible discovery across diverse diseases. The platform measures antibody binding to 1,800+ full-length, correctly folded human proteins – preserving conformational epitopes for highly specific and biologically relevant autoantibody detection. It provides valuable insight into immune responses in health, disease and treatment.
With the MACS® Matchmaker you can experience a robust platform that delivers quantitative data on binder affinity, kinetics, and specificity in complex samples. Unlock new possibilities in your research today – because every target deserves its perfect match!
PDX Models Empower your research with models that reflect today’s patients and treatments.
Weigh, image and mark glass and plastic vials, all in one compact benchtop unit - this is MultiVial. Modular & configurable to your exact requirements, this versatile system offers fast and efficient processing of vials for your lab.
The SCISSOR is an in-vitro subcutaneous injection site simulator that provides biopharma scientists insights into the behavior of their sub-Q drug candidates.
Unlock deeper insights into tissue organization and cellular interactions with Crown Bioscience’s spatial biology and digital pathology services, featuring advanced imaging, automated analysis, and high-throughput biomarker screening for applications in cancer research, immunology, and more.
Unified software platform for easy and efficient instrument control and data evaluation of Biacore™ 1 series and Biacore 8 series SPR systems, with the option to integrate into GxP- regulated workflows.
Explore your translational research with Crown Bioscience’s comprehensive genomics services—offering PCR/qPCR, next-generation sequencing, and advanced bioinformatics to deliver high-quality, reproducible data for biomarker discovery and drug development.
Human Claudin-6 Full Length Protein (VLP) (CL6-H52P7) is expressed from human 293 cells (HEK293). Virus-like particles(VLPs) are formed by self-assembly of envelop/capsid proteins from viruses. Membrane Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures.
From small-scale R&D to large-scale manufacturing, Pion homogenizers deliver exceptional fluid processing for particle size reduction (micronization,) cell disruption, and the creation of stable micro- and nanoemulsions and dispersions. Built for scalability, we make the transition from lab to commercial production seamless. Trusted by pharmaceutical, biotech, cannabis, chemical, and food and beverage manufacturers worldwide.
Model 1575 Immunowash Microplate Washer
(This is the suggested replacement for 3009)Useful for the harvesting of cellsBlade design minimizes cell damage and ensures even contact with the growth surfaceDesigned for use in 25 and 75cm2 flasksIndividually wrappedSterilized by gamma radiation and certified nonpyrogenic"
Corning® Thermowell™ 96 well polycarbonate PCR microplates fit the most commonly used thermal cyclers For oil-free operation, plates must be used with sealing tape or a sealing mat and used in conjunction with thermal cyclers that have heated lids
The ideal device to accurately set and maintain temperatures.
Black microplates have low background fluorescence and minimize light scattering Designed to reduce well-to-well crosstalk High binding surface is capable of binding medium (>10kD) and large biomolecules that possess ionic groups and/or hydrophobic regions Binding capacity is approximately 400 to 500ng IgG/cm2 Ideal for immunoassays Without lids, lids supplied separately Total volume is 360 µL; recommended working volu…
V-bottom wells with 320 µL total volume Recommended working volumes of 75 to 200 µL Nonreversable lids with condensation rings to reduce contamination Treated for optimal cell attachment Sterilized by gamma radiation and certified nonpyrogenic Individual alphanumeric codes for well identification Individually wrapped
Effective adhesive seal prevents evaporation during reaction and storage Can be removed from plate without leaving any residue Autoclavable (121°C, 20 min.) Certified free of human DNA, DNase, RNase and PCR Inhibitor*1 PCR Film, adhesive Sample can be visually monitored through the transparent film PCR Foil, adhesive Easy to pierce Pipette tip does not become tacky (ideal for automated systems) *1 Certifi…
