Drug discovery > Target Discovery Products & Reviews

Agilent’s proprietary Stabilization and Drying Solution is optimized to reduce degradation of cyanine 3 and 5 by ozone during microarray processing in preparation for scanning. 

The LacSwitch II inducible mammalian expression system utilizes an improved vector system in which several elements of the lac operon have been modified for use in eukaryotic cells for the control of gene expression. The establishment of a highly regulated expression system in eukaryotic cells is an invaluable tool for the study of cell cycle, oncogenicity, cytogenicity, and the mechanisms of gene regulation.

G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. G418 Sulfate is available as a crystalline solid or in aqueous sterile solution.

RNace-it ribonuclease cocktail is a mixture of two RNases: RNase A and a nonspecific RNase from Aspergillus oryzae. The combined action of these ribonucleases results in the degradation of RNA into small oligoribonucleotides.  Mixture of RNase A and RNase T1  Combined action of these RNases degrades RNA into small oligoribonucleotides  Tested to be free of contaminating DNase activity

The Affinity protein expression and purification system provides a simple, gentle, and effective method for high-level protein expression and purification. A complete Affinity protein expression and purification system includes calmodulin (calcium-modulated protein or CaM) affinity resin and pCAL expression vectors, containing a calmodulin-binding peptide (CBP) tag.

Agilent’s mouse CpG microarrays enable a comprehensive insight into the DNA methylation changes that may be correlated to key biological processes. Such processes include cancer, development, genomic imprinting, gene silencing, and chromatin stability.

Choose the Klenow Fill-In Kit to perform both partial fill-in reactions to prepare genomic DNA for insertion into the Lambda FIX II vector, and complete fill-in of a 5 overhang to generate blunt ends, to allow direct ligation. Or, use the kit to radioactively end label a 5 overhang with [alpha- 32 P]dNTP.

The Luciferase Assay Kit provides rapid, sensitive, and quantitative measurement of American firefly (Photinus pyralis) luciferase activity in cultured mammalian cells.  Sensitive, widely used reporter assay  Rapid, quantitative results  Reporter activity immediately available upon translation  Useful in conjunction with PathDetect systems

The Mammalian Two-Hybrid Assay Kit is a powerful method for detecting protein-protein interactions in vivo in mammalian cells. The two-hybrid assay kit utilizes hybrid genes to detect protein-protein interactions via the activation of reporter-gene expression.  Detects protein-protein interactions in mammalian cells  Works well in a variety of mammalian cell lines  Confirms suspected interactions between two proteins or i…

The PCR grade deoxynucleotide mix includes 25 mM of each standard dNTP (GATC) for use with any PCR application, including real-time quantitative PCR. These reactions buffers contain the optimal magnesium concentration for efficient PCR.

The Universal Human miRNA Reference RNA is an ideal reference control for miRNA microarray or miRNA-targeted QRTPCR experiments. The Agilent miRNA Kit may also be used as an optimization or standardization reagent for human miRNA analysis. Available in industrial lots for high throughout applications.

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

Agilent Rat microRNA Microarrays generate complete microRNA expression profiles to allow broad insight into rat expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase  Optimal sensitivity and specificity through unique probe design method  8 x 15 K slide fo…

Agilent Rat microRNA Microarrays generate complete microRNA expression profiles to allow broad insight into rat expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase  Optimal sensitivity and specificity through unique probe design method  8 x 15 K slide fo…

Agilent Rat microRNA Microarrays generate complete microRNA expression profiles to allow broad insight into rat expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase  Optimal sensitivity and specificity through unique probe design method  8 x 15 K slide fo…

Agilent Rat microRNA Microarrays generate complete microRNA expression profiles to allow broad insight into rat expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase  Optimal sensitivity and specificity through unique probe design method  8 x 15 K slide fo…

Agilents High-Resolution C Scanner provides the advanced capabilities your laboratory needs to perform high-density microarray analysis. Optimized through SureScan High Resolution Technology, the dynamic range is now 20X greater than other leading scanners. Seamless data processing and the industry™s first dynamic autofocus helps deliver the clarity and quality your research requires.  Superior resolution, (10 microns down to…

Agilent’s Human ENCODE ChIP-on-chip microarray is designed to identify human DNA binding proteins within the ENCODE regions. The microarray is designed to target ENCODE regions with more than 53,000 validated probes, which are proven to deliver robust hybridization and optimal binding critical to reliable data.

Agilent SureSelect All Exon kits are the most widely used target enrichment solution for exome sequencing. SureSelect Human All Exon V5 (targeting coding regions only) and V5+UTRs (targeting coding regions plus UTRs) have been updated to provide the greatest sequencing efficiency and enable samples ready for sequencing the next day. Greater coverage with less sequencing for lower overall costs – up to 60% less sequencing than…