Drug discovery > Pre-Clinical Development Products & Reviews

Forensic Drug Testing Solutions

ELISA-based assay for the detection and quantification of global DNA methylation in human genomic DNA

Simple plate-based non-radioactive DNA-binding assays that facilitate the study of NFkB transcription factor activation in mammalian tissue and cell extracts

Simple solution for studying Nrf2 activation in human, mouse and rat model systems

Highly sensitive and rapid microplate-based assay to simplify the measurement of DNA methyltransferase activity

ELISA-based assay designed to detect and quantify 5-hydroxymethylcytosine (5-hmC) levels in genomic DNA from different sample types

Multiplex epigenetic assay for high throughput profiling of histone post-translational modifications

Simple, sensitive method for detecting changes in histone methylation levels from purified core histones or histones isolated by acid extraction

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  An extensive range of antibodies from BioPorto and Wako suitable for use in various immunoassay techniques including: ELISA, Western Blotting, Immunohistochemistry and Immunoprecipitation.   Products Include: Variability Free IgE Immunohistochemistry stains and reagents Recombinant Proteins Primary Antibodies Secondary Antibodies  

For removal of parvoviruses from therapeutic protein feed streams

OXM causes weight loss via suppression of food intake and increase in energy expenditure. OXM administration was also reported to increase heart-rate in mice. Besides regulating glucose homeostasis in monogastric animals, OXM also increases the concentration of insulin and glucose in plasma of Holstein cattle under normal physiological conditions. It has been shown that Type 2 diabetes patients have lower levels of OXM and lev…

The Ansh Labs Bioactive IGF-I kit uses a highly sensitive two-site antibody method which allows detection of bioactive IGF-I. This assay enables accurate measurement and differentiation of bioactive IGF-I from total IGF-I levels. Assessment of bioactive to total IGF-I ratio will be informative and advance our understanding of IGF-I function and regulation in different physiological and disease states.

The Total IGF-I immunoassay is a direct detection method which eliminates potential altering of sample matrix from size-exclusion chromatography or filtration methods.  

The ratio of Total to Intact IGFBP-4 concentration measured in individual subjects over time will help normalizes the IGFBP-4 variability between subjects and also increase the detection rate of increased PAPP-A activity in myocardial infarction subjects.

During pregnancy, PAPP-A is produced in high concentrations by the trophoblast and released into maternal circulation. In addition to trophoblasts, PAPP-A expression has been reported in various tissues, including endometrium, testis, atherosclerotic arteries, kidney, bone, colon, and other adult and fetal tissue.

Activin B exhibits a wide range of biological activities, including regulation of embryogenesis, osteogenesis, hematopoiesis, reproductive physiology and hormone secretion from the hypothalamic, pituitary and gonadal glands.

Solutions for Life Science

Cutting edge brain research in awake mice without the biases introduced by anesthetics.

Tedlar® gas sampling bags are recommended in many US EPA methods including TCLP and methods TO-3 (VOCs), TO-12 (NMOC), TO-14A (VOCs), TO-15 (VOCs), ASTM D-5504 (reduced sulfur compounds) and a variety of atmospheric gas methods. Tedlar® bags are an excellent value and offer several features over competitor versions.   Benefits: Unique valve and seam-sealing process ensure bags are sturdy and leak-proof under the mo…

The ToxiLight® BioAssay Kit is a bioluminescent, non-destructive cytolysis assay kit designed to measure the release of the enzyme, adenylate kinase (AK), from damaged cells. The ToxiLight BioAssay Kit also facilitates high content screening by allowing other tests to be performed on the original cells For example, the ToxiLight BioAssay Kit is fully compatible with the ReportaLight™ BioAssay Kit, thus facilitating measurement…

Samplicity G2 Starter Bundle (Glossy Green) with 0.45 µm Millex-GP Filters

Fast, contamination free grinding below 1 micron. Handles sample volumes from 1 ml up to 4 x 225 ml.

In contrast to conventional Planetary Mills, the rotational speed of the grinding bowls and supporting disk can be configured separately in the Vario-Planetary Mill PULVERISETTE 4 classic line with 2 working stations. Your advantage: A single mill for mechanical activating and alloying providing optimum grinding conditions suited to the respective material to be ground and the size of the grinding bowls and balls! For resul…

Optimized for brewing yeast, wine yeast and other small cells with one channel of fluorescence.