Drug discovery > Pre-Clinical Development Products & Reviews

An EIA for the detection of Intact Parathyroid Hormone (PTH) in human serum and plasma

An enzyme immunoassay for the quantitation of sclerostin in human serum and plasma.

2D bar-coded tube rack scanner

The dropping process has remained a highly manual technique for years, leaving an automation void between harvesters and microscopes. CellWriter now completes the continuum, by automating the dropping process to deliver quality spread interphase and metaphase nuclei for analysis. Features:Automated Cell DroppingAutomated Probe/DAPI DispensingIntegrated HybridizationImprove Metaphase Spread QualityPerform Up To 8 Assays On One…

Revolutionary 2DGE Software Analysis of single 2D gels - Dymension 1 is ideal for users looking for software to analyse spots between samples containing one 2D gel only. It offers a range of automatic image correction features and methods for resolving and analysing spots on single gels. The software can be easily upgraded to Dymension 2 or 3 if the proteomics needs of the laboratory change.

SOD or SOD-like activity detection.  WST-1 based SOD inhibition assay, colourimetric microplate measurement, measures 100% inhibition by SOD, pH-independent IC50 determination, low background noise measurement.

Abasic site quantification in genomic DNA.  Determine the number of abasic sites in genomic DNA samples, colourimetric microplate assay, detection range: 1-40 abasic sites per 1x10^5 base pairs DNA. 

Ready-to-use dialysis device with a broad built-in range of precise MWCO's and all the needed accessory components built in for ultimate convenience.  Features leak proof and re-sealable snap-on cap for sampling, colour coded dot for MWCO, broad floatation disk for buoyancy, 6 volume-specific size, 2 membrane types- biotech grade regenerated cellulose (RC) and biotech grade cellulose ester (CE).

Cellstain-Double Staining Kit is utilised for simultaneous fluorescence staining of viable and dead cells.  Flurometric microscope detection, simultaneous determination of viable and dead cells.

Calbiochem® supplies a wide variety of products for the study of apoptosis, includingActivators and Inhibitors Antibodies and Blocking Peptides Assay Kits Caspase-related products Mitochondrial Permeability-Transition Reagents and Related Products Poly(ADP-Ribose) Glycohydrolase (PARG) Inhibitors Poly(ADP-Ribose) Polymerase (PARP) Inhibitors Telomerase Products View the online interactive pathways to easily locate the product…

vHCS:View Module Desktop PC software is avalable separately from the full vHCS™ Discovery ToolBox. vHCS:View provides, Rich visualization of HCS data, allowing users to see spatial, temporal, morphological and phenotypic changes at the cell levelInteractive visual analysis of multi-feature, cell-based data  to the image levelLink to Spotfire® DecisionSite™ for deeper visualization and data miningMulti-plate, multi-well, multi-…

Cellomics® Content Addressed Storage (CAS) Module for EMC Centera™ is an HCS Applications Server plug-in that provides an interface to the EMC Centera content addressed storage system. Centera is EMC’s newest storage platform specifically designed to work with large volumes of fixed content information, such as the many terabytes of images generated by HCS instrumentation. The CAS Module allows HCS image data to be seamlessly…

The Micronucleus V2 BioApplication is a powerful image analysis algorithm for identifying and quantitating the rare event of micronucleus formation as a measure of genotoxicity.  Because it can screen a 96-well plate in under 8 hours, it enables screening for genotoxic compounds in an automated, objective manner.  This application has been biologically validated, enhancing confidence in your image-based data.  Available for th…

Molecular Translocation V2 is an advanced image analysis application for quantitating simultaneous cytoplasm-to-nucleus translocation of multiple targets.  It features subpopulation selection and cross-correlated responder analysis of up to 5 distinct targets, allowing study of signaling pathways.  This application has been biologically validated, enhancing confidence in your image-based data.    Available for the Cellomics Ar…

Morphology Explorer V2 is a powerful general-purpose image analysis application for measuring size, shape, and distribution of cells, colonies, and subcellular components.  It performs sophisticated calculations in a turn-key, automated manner allowing higher throughput of complex cell-based assays.  This application has been biologically validated, enhancing confidence in your image-based data.    Available for the Cellomics…

Cell Health Profiling V2 is a flexible image analysis application employing advanced cell-level logic to detect and classify cell health-related events.  It analyzes patterns of cellular fluorescent labeling that can be used to classify cells as undergoing apoptotic, necrotic, or other cell death mechanisms.  This application has been biologically validated, enhancing confidence in your image-based data.  Available for the Cel…

The Cell Cycle V2 BioApplication is a sophisticated image analysis algorithm that performs automated analysis of the cell cycle phase of individual and populations of cells.  It reports cell cycle phase as well as the state of up to 3 target proteins for every cell analyzed, and correlates the target data with DNA content.  This application has been biologically validated, enhancing confidence in your image-based data.  Availa…

The Cytotoxicity V2 BioApplication is an image analysis application that simultaneously measures four markers of cytotoxicity (nuclear fragmentation/condensation, permeability, lysosomal mass-pH, and cell count) and reports individual and composite indicies of cytotoxicity.  The V2 version has been enhanced with object segmentation to allow clumped cells to be efficiently analyzed.  Available for the Cellomics ArrayScan VTI, A…

Extended Neurite Outgrowth V2 is an advanced image analysis algorithm that can quantitate neurite outgrowth with features such as cell body area and branch point quantitation, cell subpopulation analysis, Ability to analyze neuron subsets expressing up to two distinct neurotransmitters.  It reports all features at the cell, well, and subpoulation level, and is biologically validated to enhance confidence in your image-based da…

Compartmental Analysis V2 is a powerful general image analysis tool for quantitating intracellular intensity changes in specific sub-cellular regions across multiple fluorescent channels.  It performs spot analysis and reports intensity ratios and differences among sub-cellular regions and/or different fluorophores.  This application has been biologically validated, enhancing confidence in your image-based data.  Available for…

The Cell Motility V2 BioApplication is a advanced image analysis algorithm for measuring the overall motility of cells.  It quantitates total distance traveled by each cell exposed to growth factor or compound for a quantiative assessment of cell motility.  The V2 version includes advanced analytical capabilities such as population analysis and object segmentation.  This application has been biologically validated, enhancing c…

Spot Detector V2 performs measurements of number, size, and other features of spots in cells.  It is an easy-to-use and essential component of any image analysis software suite.  This tool is excellent for measuring receptor internalization and trafficking, cell proliferation and counting, Analyzing populations. This application has been biologically validated, enhancing confidence in your image-based data.  Available for the…

The Cell Spreading V2 BioApplication is an image analysis algorithm for measuring size and shape of cells.  It utilizes cells labeled with cytotskeletal fluorescent reagents to report whether cells have rounded in response to compound treatment, and includes advanced features such as population characterization and object segmentation.  This application has been biologically validated, enhancing confidence in your image-based…

The Neurite Outgrowth V2 BioApplication is a streamlined image analysis algorithm for morphological analysis of neurite outgrowth. Utilizes fluorescent images of neurons and neurites stained for tubulin to quantitate the number and length of neurites in a population of cells.  This application has been biologically validated, enhancing confidence in your image-based data.  Available for the Cellomics ArrayScan VTI, ArrayScan x…

Cyto-Cell Membrane Translocation V2 is a multi-channel image analysis algorithm for analysis of targets that translocate from cytoplasm to cell membrane.  It utilizes colocalization of fluorescent markers to report whether the target is co-localized to the membrane, and reports cells' behavior relative to a control population.   This application has been biologically validated, enhancing confidence in your image-based data.  A…