Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.
DNASIS - The Most Comprehensive Software Package for Sequence Analysis. All you expect from gene analysis programs is available in DNASIS. In fact, sequence analysis customers have used versions of DNASIS for over 10 years. Hitachi DNASIS has been proven on the job by scientists worldwide to be quick, accurate and reliable. Features of DNASIS include:Comprehensive : an exhaustive list of highly developed sequence analysis…
Sorcerer UDS provides flexible approach to the UDS assay based upon our Sorcerer automatic image analysis system. The system is a fully validated suite of software for UDS compliant with Good Laboratory Practice and FDA 21 CFR Part 11, consisting of a series of modules for creating studies, randomisation, slide scoring, data saving and production of experimental summaries. Interactive automated scoring with calculation of n…
These Corning® syringe filters have acrylic copolymer housings, female Luer lock inlets and male Luer slip outlets. Surfactant-free cellulose acetate (SFCA) membranes provide the lowest protein binding 100% integrity tested, sterile and certified nonpyrogenic and noncytotoxic Manufactured in accordance with ISO 9001 standards
Fits plastic or glass media bottles with 45mm neck sizes. Cellulose acetate (CA) membranes provide fast flow rates and low protein binding and are good for filtering cell culture media. Angled hose connector simplifies vacuum line attachment. Individually packaged, sterile and certified nonpyrogenic. Each system has the membrane material and pore size printed on the unit and is color-coded by membrane type for easy produ…
These Corning® syringe filters have polypropylene copolymer housings, female Luer lock inlets and male Luer slip outlets. Regenerated cellulose (RC) membranes are the best choice for DMSO compatibility. 100% integrity tested, sterile and nonpyrogenic and noncytotoxic Manufactured in accordance with ISO 9001 standards
Fits plastic or glass media bottles with 45mm neck sizes. Nylon (NY) membranes are naturally hydrophilic, surfactant-free and offer the lowest extractables. Angled hose connector simplifies vacuum line attachment. Individually packaged, sterile and certified nonpyrogenic. Each system has the membrane material and pore size printed on the unit and is color-coded by membrane type for easy product identification. Expiratio…
One dial setting delivers a consistent and safe anesthetic level. Manuals include a "cookbook" protocol which can easily be adapted to your facility's SOP. All waste gases are scavenged for easy evacuation. Breathing circuits allow flat, prone or supine positions with head access. Suitable for mouse, rat, hamster, gerbil, guinea pig, ferret, rabbit, cat, dog or small swine.Positive sealing gasket on induction chambers minimize…
The new Bioscan BioFLECT 400 is the first in vivo optical imaging system offering true 360° fluorescence tomography. BioFLECT uses the photon emission data acquired from 360° and a state-of-the-art 3D reconstruction engine to quantitatively reconstruct the 3D spatial distribution of fluorescent probes in live animals. This approach yields superior, consistent resolution, sensitivity and quantitation throughout the subject. The…
Spectral Instruments Imaging's LAGO offers high throughput imaging for BLI & FLI. With 10 mouse campacity, the LAGO is a fantastic option for high volume imaging cores. This workhorse is designed for non-stop imaging and is the gold standard in sensitiviy - 36% more sensitive than the leading competitor. The LAGO also provides Absolute Calibration, -90C Air Cooled CCD Camera, LED Fluorescence excitation and free software.
The Tube Auditor™ measures sample volumes and detects precipitate using high-speed vision technology. It gives confidence in the quality of your samples (at both collection and output) and helps reduce downstream costs and waste, which can arise from empty wells and precipitated samples. Applications include Compound Management, High Throughput Screening and Biobanking.
The Pippin Link Group Control is the best way to reproducibly provide the highest quality size-selected DNA in high-throughput. It provides hardware and software for running up to eight Pippin Instruments from a laptop PC. Three linked-Pippins can produce up to 96 size selections in one day.
WHEATON BioBanking Solutions is a comprehensive offering of high quality products and customized services for your cryogenic needs.Whether you require the storage of irreplaceable samples in glass cryogenic ampules or plastic cryogenic vials, bar coding options for sample traceablity or for color coded storage and freezer boxes, WHEATON provides you with the tools that make your job easier and more efficient while having the c…
Gerhardt has created a complete line of Soxtherm models, creating the ideal opportunity to have a state of the art lab for Extraction systems. One of the most impressive units in the line is the Soxtherm 416, capable of six extraction places capable of holding both small and large beakers. The unit is capable of nearly all analytical areas in fat determination and sample preparation specifically: milk, cereal, meat, oil, fruit…
Being able to visualize endogenous cellular structures in live cells is key for many high content analyses. The two Chromobodies® of the ChromoTek’s Cell Organelle Toolbox offer a new way to investigate key compartments of the cell non-invasively. Lamin-Chromobody® The new Lamin-Chromobody® is a major breakthrough especially in High-Content Analysis (HCA) as apoptosis assays thus far rely on static endpoint assays. The nucle…
Disposable cuvettes for spectrophotometry, optical PS visible range cuvettes, UV Grade PMMA cuvettes. Standard and semi-micro disposable cuvettes for spectroscopy made of optical PS and PMMA UV grade optical windows to achieve optimal transmittance through spectral range from 340 to 800 nm (OPS) an from 280 to 800 nm (PMMA UV qrade). The engineering and quality control determine the reproducibility of the cuvettes. These are s…
The BD FocalPoint™ is an automated imaging system that can assist in the primary screening of BD SurePath™ liquid based cytology slides and is currently used worldwide. Up to 288 slides can be loaded onto the system at the same time with the capacity to load additional slides during the working day. The system can operate 24 hours continually over a 7 day period and is monitored remotely by the manufacturer Becton Dickinson v…
The FlowCellect™ Human NK Cell Characterization Kit includes three directly conjugated antibodies, Anti-CD3-APC, Anti-CD56-PE, and Anti-CD16 FITC. This three color kit is designed to characterize NK within mixed cell populations. The antibodies provided have been carefully titrated to ensure the ability to accurately measure the expression of all markers simultaneously. Sufficient reagents are provided to perform 25 three-colo…
The fastest way to understand the biological meaning of your expression data Rapidly Identify Biologically Compelling Transcript Changes:Ingenuity® iReport™ is an interactive web-based report, optimized for gene expression experiments from – RNA-Seq, microarray, and real-time PCR platforms, that provides a fast and accurate biological and statistical analysis of your experimental data.
iCell® Hepatocytes, derived from human induced pluripotent stem (iPS) cells, provide access to commercial quantities of high quality, high purity human liver cells for preclinical drug discovery, hepatotoxicity testing, and disease research. iCell® Hepatocytes express alpha-1-antitrypsin (AAT), asialoglycoprotein receptor (ASGR1), hepatocyte nuclear factor 4 alpha (HNF4A), and secrete albumin at levels similar to adult primary…
An enzyme immunoassay for the quantitation of 25-OH Vitamin D in human serum.
Millipore’s FlowCellect™ DNA Damage (Histone H2A.X) and Cell Cycle Analysis Kit is designed to identify the linkage between DNA damage in relation to cell cycle checkpoints in flow cytometry applications. The kit includes a directly conjugated Anti-phospho-Histone H2A.X (Ser139) Alexa Fluor® 488 antibody plus a DNA dye (Propidium Iodide) which allows the researcher to perform bivariate analysis to identify where DNA damage ta…
Millipore’s FlowCellect™ DNA Damage (ATM) and Cell Cycle Analysis Kit is designed to identify the linkage between DNA damage in relation to cell cycle checkpoints in flow cytometry applications. The kit includes a directly conjugated Anti-phospho-ATM (Ser1981) Alexa Fluor® 488 conjugate plus a DNA dye (Propidium Iodide) which allows the researcher to perform bivariate analysis to identify where DNA damage takes place relativ…
Millipore’s FlowCellect™ Bivariate Cell Cycle Kit for DNA Replication Analysis is designed to investigate cells undergoing replication in S-phase of the cell cycle with high accuracy and confidence in flow cytometry applications. The kit includes a directly conjugated Anti-BrdU Alexa Fluor® 488 conjugate plus a DNA dye (Propidium Iodide) which allows the researcher to perform bivariate analysis to distinguish cells in two dim…
Millipore’s FlowCellect™ Bivariate Cell Cycle Kit for G2/M Analysis is designed to allow the researcher to easily identify, discriminate, and quantitate cells between the G2 and M-phases of the cell cycle. The kit can be used to perform bivariate analysis to measure cell cycle distributions by discrimination of cell cycle phases without the need of sophisticated software modules or algorithms. Having the ability to distingui…
Millipore’s FlowCellect™ Multi-Color DNA Damage Response Kit is designed to enable a researcher a quick and easy way to detect the phosphorylation state of ATM, SMC1 and Histone H2A.X by flow cytometry. Millipore’s FlowCellect™ Multi-Color DNA Damage Response Kit was developed and tested using the DNA damaging reagent, Etoposide, in HeLa cells as a model system but the kit can be used with other human cell lines to determine…
