Drug discovery > Pre-Clinical Development Products & Reviews

High Quality Assays with Reproducible and Reliable Results

PathXL™ Simulator is a comprehensive diagnostic training package aimed at supporting early stage training for residents in pathology. We call this unique approach “learning by simulation” since trainees can work through real cases and assess how well they have performed. This approach to training has been completely embraced by numerous laboratories across the world including the Thames and Medway Training Schools, Liverpool t…

Extra powerful premium pre-crushing

The 6875 Freezer/Mill® is a large cryogenic mill that accommodates sample sizes ranging from 0.1 - 100 grams. Specifically designed for cryogenic grinding and pulverizing tough and/or temperature sensitive samples in a grinding vial immersed in liquid nitrogen. The new high resolution display is user-friendly and shows the each stage of the grinding process. It also shows the Run history, Training videos and manuals and a…

The Shatterbox® is a heavy duty, Swing Mill that is designed for pulverizing dry, brittle samples and slurry grinding. It features a sound-proof enclosure and a timer display that counts down the minutes and seconds remaining in the process. It accommodates sample sizes ranging from 2 - 100 grams and is capable of grinding Cement, Soils, Ceramics, Slag, Rocks, Minerals, Ores, Pharmaceuticals, Sulfur Pellets, Dried Plant Ma…

The 6875D Freezer/Mill® is a high-throughput, dual chamber cryogenic grinder with a self-contained liquid nitrogen tub and insulated case. Specifically designed for cryogenic grinding and pulverizing of tough and/or temperature sensitive samples in a grinding vial immersed in liquid nitrogen. This mill chills samples in liquid nitrogen then pulverizes them with a magnetically driven impactor. The new high resolution displa…

The 8000D Mixer/Mill® is a dual clamp, high-energy ball mill that grinds dry, brittle samples such as Rocks, Minerals, Sand, Cement and Slag. It can also be utilized for mechanical alloying, slurry grinding, blending powders and mixing emulsions. It accommodates sample sizes ranging from 0.2 - 10 grams per vial and has a figure eight motion that has been proven to be more efficient than side-to-side or planetary motion fou…

Fast analysis of particle shape and size of suspensions and emulsions!

The LH96 can be configured to combine multiple sample prep steps into one versatile, efficient and automated device. Quite literally, what used to take hours or days can now be completed in a matter of minutes, and without attendance. The LH96 integrates a core homogenizing platform, capable of efficiently processing a wide variety of samples from 5mL to 50mL tubes, with fully customizable liquid handling capabilities. Patent…

DPX new – without teratogenic DBP plasticizer for use in histology processes with xylene. In histology, users are in frequent contact with hazardous reagents. During fixation, histoprocessing, staining and mounting, laboratory technicians and pathologists are surrounded by solvents and solvent-containing solutions. These can cause health problems, as they may, for example, be carcinogenic or teratogenic. Di-N-Butyl Ph…

An EIA for the detection of Circulating Immune Complexes via C1q binding in human serum, plasma and other biological or experimental samples

An EIA for the detection of functional C1 inhibitor in human serum, plasma and other biological or experimental samples

An EIA for the detection of Deoxypyridinoline crosslinks (DPD) in human urine

An EIA for the detection of Intact Parathyroid Hormone (PTH) in human serum and plasma

An enzyme immunoassay for the quantitation of sclerostin in human serum and plasma.

2D bar-coded tube rack scanner

Revolutionary 2DGE Software Analysis of single 2D gels - Dymension 1 is ideal for users looking for software to analyse spots between samples containing one 2D gel only. It offers a range of automatic image correction features and methods for resolving and analysing spots on single gels. The software can be easily upgraded to Dymension 2 or 3 if the proteomics needs of the laboratory change.

SOD or SOD-like activity detection.  WST-1 based SOD inhibition assay, colourimetric microplate measurement, measures 100% inhibition by SOD, pH-independent IC50 determination, low background noise measurement.

Abasic site quantification in genomic DNA.  Determine the number of abasic sites in genomic DNA samples, colourimetric microplate assay, detection range: 1-40 abasic sites per 1x10^5 base pairs DNA. 

Ready-to-use dialysis device with a broad built-in range of precise MWCO's and all the needed accessory components built in for ultimate convenience.  Features leak proof and re-sealable snap-on cap for sampling, colour coded dot for MWCO, broad floatation disk for buoyancy, 6 volume-specific size, 2 membrane types- biotech grade regenerated cellulose (RC) and biotech grade cellulose ester (CE).

Cellstain-Double Staining Kit is utilised for simultaneous fluorescence staining of viable and dead cells.  Flurometric microscope detection, simultaneous determination of viable and dead cells.

Calbiochem® supplies a wide variety of products for the study of apoptosis, includingActivators and Inhibitors Antibodies and Blocking Peptides Assay Kits Caspase-related products Mitochondrial Permeability-Transition Reagents and Related Products Poly(ADP-Ribose) Glycohydrolase (PARG) Inhibitors Poly(ADP-Ribose) Polymerase (PARP) Inhibitors Telomerase Products View the online interactive pathways to easily locate the product…

vHCS:View Module Desktop PC software is avalable separately from the full vHCS™ Discovery ToolBox. vHCS:View provides, Rich visualization of HCS data, allowing users to see spatial, temporal, morphological and phenotypic changes at the cell levelInteractive visual analysis of multi-feature, cell-based data  to the image levelLink to Spotfire® DecisionSite™ for deeper visualization and data miningMulti-plate, multi-well, multi-…

Cellomics® Content Addressed Storage (CAS) Module for EMC Centera™ is an HCS Applications Server plug-in that provides an interface to the EMC Centera content addressed storage system. Centera is EMC’s newest storage platform specifically designed to work with large volumes of fixed content information, such as the many terabytes of images generated by HCS instrumentation. The CAS Module allows HCS image data to be seamlessly…

The Micronucleus V2 BioApplication is a powerful image analysis algorithm for identifying and quantitating the rare event of micronucleus formation as a measure of genotoxicity.  Because it can screen a 96-well plate in under 8 hours, it enables screening for genotoxic compounds in an automated, objective manner.  This application has been biologically validated, enhancing confidence in your image-based data.  Available for th…