Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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EVE HT FL: High-throughput Fluorescence Cell Counter

NanoEntek

The EVE™ HT FL is a high-throughput automated fluorescence cell counter equipped with bright field and two fluorescence channels (AO/DAPI). In just 3 minutes, up to 48 samples can be counted and analyzed. EVE™ HT FL delivers brilliant precision and accuracy, making it the optimal choice for both cell lines and primary cell analysis in a variety of applications.

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Metabolomic Products

Cambridge Isotope Laboratories

An innovative technology termed isotopic ratio outlier analysis (IROA) was developed to overcome the analytical challenges associated with current, stable isotope labeled compounds used in untargeted /targeted metabolic profiling.   These challenges minimally pertain to analytical variance, artifactual peaks, and metabolite identification. The IROA method uses metabolic incorporation of heavy (95% 13C) and light (5%…

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Oxyntomodulin (OXM) ELISA

Ansh Labs

OXM causes weight loss via suppression of food intake and increase in energy expenditure. OXM administration was also reported to increase heart-rate in mice. Besides regulating glucose homeostasis in monogastric animals, OXM also increases the concentration of insulin and glucose in plasma of Holstein cattle under normal physiological conditions. It has been shown that Type 2 diabetes patients have lower levels of OXM and lev…

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Bioactive IGF-I ELISA

Ansh Labs

The Ansh Labs Bioactive IGF-I kit uses a highly sensitive two-site antibody method which allows detection of bioactive IGF-I. This assay enables accurate measurement and differentiation of bioactive IGF-I from total IGF-I levels. Assessment of bioactive to total IGF-I ratio will be informative and advance our understanding of IGF-I function and regulation in different physiological and disease states.

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IGFBP-4 (Total or Intact) ELISA

Ansh Labs

The ratio of Total to Intact IGFBP-4 concentration measured in individual subjects over time will help normalizes the IGFBP-4 variability between subjects and also increase the detection rate of increased PAPP-A activity in myocardial infarction subjects.

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