Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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709-DS Dissolution Apparatus

Agilent Technologies

Using the same platform as the 708-DS, the 709-DS Dissolution Apparatus ensures productivity, reproducibility and ease of use combined with the convenience of a bath-free design. The 709-DS reduces media heating time with Direct Vessel Heating (DVH) capabilities while insulating the vessel from environmental factors and eliminating water bath cleaning. The exclusive design of the chemically resistant, DVH TruAlign vessel incor…

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LC Dissolution Software

Agilent Technologies

Agilent's LC Dissolution Software is an add-on module to the ChemStation Edition of the OpenLAB Chromatography Data Systems. The software controls the analysis of dissolution samples and calculates final dissolution results. In combination with OpenLAB ECM or OpenLAB Data Store, all tools for 21 CFR Part 11 compliance such as access control, data security, data integrity, electronic signatures and archival are provided. Feat…

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Thermal Separation Probe

Agilent Technologies

The Agilent Thermal Separation Probe (TSP) provides fast analysis of solid, liquid, and slurry samples. The process is simple, clean, and requires limited or zero sample preparation. Non-vaporized high boiling point ‘dirty sample matrix’– compounds, which can contaminate the GC liner and column, remain inside the micro-vial, and can be discarded after each injection. Use the TSP when testing complex samples in food, forensics,…

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NovoCyte Penteon Flow Cytometer

Agilent Technologies

The NovoCyte Penteon flow cytometer builds on its successful predecessor, the NovoCyte, and provides an expanded set of capabilities that accommodate today’s high-end and increasingly sophisticated multi-color flow cytometry assays. You now have the flexibility to choose from up to 30 fluorescence channels utilizing up to 5 lasers with up to 30 independent detectors. The NovoSampler Q can be integrated into different laborator…

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Agilent 708-DS Dissolution Apparatus

Agilent Technologies

The 708-DS dissolution apparatus is a modular system designed for manual or automated dissolution testing. The instrument can be configured for use with baskets (Apparatus 1), paddles (Apparatus 2), paddle over disk assemblies (Apparatus 5), and rotating cylinders (Apparatus 6), and can accommodate vessel sizes from 100 mL to 2 L.

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Agilent NanoDis System

Agilent Technologies

The NanoDis System provides formulation scientists with accurate release profiles of APIs using conventional dissolution apparatus in an automated, compliant manner. This functionality enables analysts to uncover the best nanoparticle formulation faster and get new drug formulations to market more quickly.  

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Streptavidin

Agilent Technologies

SA10 Streptavidin (formerly ProZyme) is Agilent's longest-established streptavidin product, being a widely-used workhorse of the industry for over 25 years. It is purified to a high degree from fermentations of Streptomyces avidinii and has a molecular weight of 52 kDa (also known as 'core' streptavidin). Agilent also offer a variant of streptavidin (SA26 Streptavidin-plus), which is made as a recombinant form in E. coli an…

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Seahorse XF Mito Tox Assay Kit

Agilent Technologies

The kit is designed to use with Agilent Seahorse XF Pro analyzer for easily identifying drug-induced mitochondrial toxicity, to de-risk your drug pipeline.  It provides high sensitivity and specificity, reducing false positive and false negatives.  It is applicable to screen compound libraries with a throughput of 80 compounds per plate.  Assay performance metrics Z’ of > 0.5 is achievable following our assay workflow. 

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xCELLigence RTCA HT-BioTek BioSpa8 – Screening Model

Agilent Technologies

Integration of the xCELLigence Real Time Cell Analyzer (RTCA) HT instrument with the BioTek BioSpa 8 automated incubator expands the screening throughput of your RTCA HT instrument to eight 384-well plates. Label-free high-throughput xCELLigence Real-Time Cell Analysis is ideal for screening viral mediated cytopathic effects (CPE), neutralizing antibodies, antibody-dependent cytotoxicity (ADCC), and compound mediated cytotoxi…

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Labware Racks

Agilent Technologies

Agilent Automation Solutions labware racks facilitate the transfer of labware between workstations, systems, or devices.The racks come in three styles and four different capacities.  The racks are universally compatible with both the BenchCel Microplate Workstation and the BioCel System.

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KREX i-Ome Discovery Services

SomaLogic

KREX™ i-Ome™ Discovery Services enable highly multiplexed autoantibody profiling for rapid, reproducible discovery across diverse diseases. The platform measures antibody binding to 1,800+ full-length, correctly folded human proteins – preserving conformational epitopes for highly specific and biologically relevant autoantibody detection. It provides valuable insight into immune responses in health, disease and treatment.

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Exosome Isolation and Studies

BioIVT

BioIVT provides isolated exosomes from a variety of human, animal, and plant sources, as well as custom characterization and in vitro assays investigating function and potential therapeutic benefit.

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