Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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Infliximab Total Anti-drug ELISA (IDKmonitor®)

BIOHIT HealthCare Ltd (UK)

Determination of total anti-infliximab antibodies Infliximab is a recombinant protein used to treat inflammatory bowel disease (IBD). The protein can induce humoral immune responses and lead to anti-drug antibody formation, a major cause of loss of drug response. IDKmonitor Infliximab Total Anti-drug ELISA kit is a ‘drug tolerant’ assay that enables the detection of anti-drug antibodies in the presence of circulating drug.

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Adalimumab Total Anti-drug ELISA (IDKmonitor®)

BIOHIT HealthCare Ltd (UK)

Determination of total anti-adalimumab antibodies Adalimumab is a recombinant protein used to treat inflammatory bowel disease (IBD). This protein can induce humoral immune responses and lead to anti-drug antibody formation, a major cause of loss of drug response. The IDKmonitor Adalimumab Total Anti-drug ELISA kit is a ‘drug tolerant’ assay that enables the detection of anti-drug antibodies in the presence of circulating dru…

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1D/2D Scanner

AgileBio

Discover our Flat 1D/2D Scanner - Single Tubes, a high-quality, low-cost solution for laboratory sample management. This scanner reads both 1D and 2D barcodes with lighting-fast speed and high resolution, ensuring accurate data capture. Its plug-and-play installation makes it easy to set up, and its highly responsive design allows for seamless operation. Simply place the tube on the scanner, and the decoded value is automatic…

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Corning® 150 mL Bottle Top Vacuum Filter, 0.22 µm Pore 13.6cm² CA Membrane, Fits 33 mm Diameter Necks, Sterile, 48/Case

Corning Life Sciences

Fits plastic or glass media bottles with 33mm neck sizes. Cellulose acetate (CA) membranes provide fast flow rates and low protein binding and are good for filtering cell culture media. Angled hose connector simplifies vacuum line attachment. Individually packaged, sterile and certified nonpyrogenic. Each system has the membrane material and pore size printed on the unit and is color-coded by membrane type for easy produ…

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Corning® 500 mL Bottle Top Vacuum Filter, 0.45 µm Pore 33.2cm² CA Membrane, Fits 45 mm Diameter Necks, Sterile, 12/Case

Corning Life Sciences

Fits plastic or glass media bottles with 45mm neck sizes. Cellulose acetate (CA) membranes provide fast flow rates and low protein binding and are good for filtering cell culture media. Angled hose connector simplifies vacuum line attachment. Individually packaged, sterile and certified nonpyrogenic. Each system has the membrane material and pore size printed on the unit and is color-coded by membrane type for easy produ…

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Formulations E-Lab Notebook

Symyx

Symyx Software Formulations Notebook is an Electronic Laboratory Notebook (ELN) designed specifically to solve the challenges faced by pharmaceutical, chemical, and personal-product formulators. Symyx Formulations simplifies information management, saves time, and improves data and formulation quality. Prepare: Design Formulations Efficiently Searchable global database of formulations, analytical data, and other associat…

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Analytical E-Lab Notebook

Symyx

Symyx Software Analytical Notebook is an Electronic Laboratory Notebook (ELN) specifically designed to enable analytical chemists to use prior experience, develop new methods, access relevant information, and integrate to critical systems to be more efficient and effective. Prepare: Design experiments and data templates Flexible data entry tools allow scientists to plan all types of experiments, including method developme…

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Corning® 28 mm Diameter Syringe Filters, 0.2 µm Pore SFCA-PF Membrane, Sterile, Individually Packaged, 50/Case

Corning Life Sciences

These Corning® syringe filters have acrylic copolymer housings, female Luer lock inlets and male Luer slip outlets. SFCA-PF (surfactant-free cellulose acetate with prefilter) membranes provide the lowest protein binding and have an integral glass fiber prefilter for extra filtering capacity 100% integrity tested, sterile and certified nonpyrogenic and noncytotoxic Manufactured in accordance with ISO 9001 standards

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Cell Cycle™ Assay

Merck

For researchers who want to do cell cycle research at their benchtop, Guava Cell Cycle assay can be used for measuring G0/G1, S, and G2/M phase distributions. Based on the established method of whole-cell staining with propidium iodide (PI), Guava's cell cycle assay is easy to learn. Guava Cell Cycle software includes markers that can be set for quick assessment of G0/G1, S, and G2/M phase cell cycle percentages as data is bei…

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Apoptosis Assay Suite

Merck

Apoptosis, or programmed cell death, is a highly regulated pathway that is important in normal developmental processes as well as many diseases. Cells undergoing apoptosis are identifiable by a number of characteristics, including changes in mitochonrial membrane potential, transport of phosphatidylserine (PS) to the membrane surface, activation of caspase proteases, and DNA fragmentation in the nucleus. Guava offers four apop…

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ViaCount™ Assay

Merck

Guava Technologies' ViaCount assay is revolutionizing the way cell counting and viability assessment are done in today's laboratories. Fast, automated, and highly reproducible, the Guava ViaCount assay addresses many of the difficulties of conventional cell counting and viability assessment methods. The Guava ViaCount assay provides: Cell counts up to ten times faster than manual counting, in a convenient turnkey assay.…

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Corning® 150 mL Bottle Top Vacuum Filter, 0.22 µm Pore 13.6cm² CA Membrane, Fits 45 mm Diameter Necks, Sterile, 48/Case

Corning Life Sciences

Fits plastic or glass media bottles with 45mm neck sizes. Cellulose acetate (CA) membranes provide fast flow rates and low protein binding and are good for filtering cell culture media. Angled hose connector simplifies vacuum line attachment. Individually packaged, sterile and certified nonpyrogenic. Each system has the membrane material and pore size printed on the unit and is color-coded by membrane type for easy produ…

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