Life Sciences Products & Reviews

Octet® FAB2G biosensors come pre-immobilized with a high-affinity ligand that is specific for the CH1 region of Human IgG. The anti-human CH1 ligand has no recognition towards free light chains or cross-reactivity with murine or bovine IgG. This high level of specificity enables direct analysis of IgG or Fab analytes directly from complex samples such as cell culture supernatants, lysates, or partially purified samples, offer…

Octet® AHQ biosensors provide a rapid method for precise quantitation of human immunoglobulins from crude lysates and cell culture supernatants. Factory immobilization of an anti-human IgG antibody onto the biosensor surface enables direct detection of human IgG analytes with minimal sample handling and facilitates sample quantitation from cell culture screening through downstream purification development.

Octet® ProA biosensors are coated with Protein A and enable rapid antibody quantitation from crude lysates, cell culture supernatants and complex matrices.

Octet® Streptavidin (SA) Biosensors are coated with streptavidin and can be easily customized for various applications, including rapid kinetic analysis, screening and quantitation of most proteins. Octet® SA Biosensors are offered in a tray format. Each tray contains 96 biosensors.

Octet® AMQ biosensors provide a rapid method for precise quantitation of murine immunoglobulins from crude lysates and cell culture supernatants. 

Octet® APS Biosensors are coated with aminopropylsilane and provide a convenient method for hydrophobic based immobilization of most protein analytes for assaying the kinetic profile of protein-protein interactions. 

Octet® SSA (Super Streptavidin) Biosensors offer the highest sensitivity for the demands of small molecule kinetic experiments.

Octet® Anti-Human Fc Capture (AHC) Biosensors are designed for kinetic characterization of interactions between human Fc-containing proteins and target analytes. Octet® AHC Biosensors are offered in a tray format. Each tray contains 96 biosensors. Larger orders include discounts.

Host cell proteins (HCPs) are contaminants found in biopharmaceuticals expressed in bacterial, yeast or mammalian production cell lines. Among protein expression cell lines, Chinese hamster ovary (CHO) cells are the most commonly used mammalian hosts for industrial production of recombinant protein therapeutics. However, manufacturing and production processes of biopharmaceuticals often leave behind contaminating HCPs fr…

Octet® Anti-Mouse Fc Capture (AMC) Biosensors are designed for kinetic characterization of interactions between mouse Fc-containing proteins and target analytes. Octet® AMC Biosensors are offered in a tray format. Each tray contains 96 biosensors.

The Octet® Amine Reactive 2nd Generation (AR2G) Biosensors are designed for EDC/Sulfo-NHS based immobilization of primary amine containing biomolecules and kinetic characterization of their interactions with target analytes. The use of the AR2G Biosensors requires the Amine Coupling Second-Generation Reagent Kit (AR2G Kit, Item no.: 18-5095). Octet® AR2G Biosensors are offered in a tray format. Each tray contains 96 biosensor…

The Octet® Amine Reactive 2nd Generation (AR2G) Biosensors are designed for EDC/Sulfo-NHS based immobilization of primary amine containing biomolecules and kinetic characterization of their interactions with target analytes. The use of the AR2G Biosensors requires the Amine Coupling Second-Generation Reagent Kit (AR2G Kit, Item no.: 18-5095). Octet® AR2G Biosensors are offered in a tray format. Each tray contains 96 biosensor…

The Octet® Anti-HIS (HIS2) Biosensors are designed for label-free quantitation of HIS-tagged proteins. Octet® HIS2 Biosensors are offered in a tray format. Each tray contains 96 biosensors.

Octet® SAX biosensors are high precision streptavidin biosensors that were specifically developed and qualified for applications in drug discovery and quality control labs that have stringent requirements for assay precision and robustness in quantitation and binding kinetics characterization assays.

The polyhistidine protein tag (His-tag), commonly engineered into proteins during cloning, can be used to facilitate recombinant protein purification and detection by exploiting the chelating properties of histidine to an immobilized metal. The Octet® HIS1K Biosensors consist of high affinity, high specificity Penta-His antibody pre-immobilized on a fiber optic biosensor. In conjunction with the Octet® systems, the Octet® HIS…

The Ready BLI Detection Kit - Residual Protein A (RPA) applies the principles of Bio-Layer Interferometry (BLI) to enable sensitive, accurate quantitation of leached Protein A in bioprocess samples while maintaining a simple workflow. The kit utilizes a validated sample treatment method for dissociating Protein A from antibodies that does not require boiling, neutralization, or centrifugation steps.

The Octet® Sialic Acid (GlyS) Kit is designed for a rapid high-throughput relative Sialic Acid content screening during early clone selection stages in Cell Line Development (CLD). The kit allows to conveniently screen and rank both crude and purified mAb and non-mAb protein samples.

Streptavidin-coated surfaces are widely used as a simple and straightforward method of molecular immobilization. Utilized with Bio-Layer Interferometry (BLI), Streptavidin biosensors enable quick and easy modification and customization of the biosensor with any biotin-tagged molecule for quantitative and kinetic measurements. The Octet® SAX2 biosensors are high precision streptavidin biosensors that were specifically develope…

The Octet® GlyM Kit enables high-throughput mannose content screening in crude cell culture samples during early clone selection stages in the CLD process.

The Octet® Anti-CHO HCP Kit is for rapid high-throughput quantitation of residual CHO host cell proteins (HCPs) in bioprocess samples. The kit utilizes industry-standard Cygnus 3G anti-CHO HCP antibody and offers high sensitivity and broad HCP recognition. Octet® Anti-CHO HCP Kit includes 1 tray of 96 biosensors, and all calibrators, reagents, and buffers necessary to analyze 96 HCP samples.

The Octet® AHC2 Biosensors are the 2nd generation of anti-human IgG Fc capture biosensors that offer significantly improved performance as well as increased versatility by enabling both quantitation and kinetic characterization of human IgG antibodies and IgG-derived Fc-fusion proteins.

Sensor chip selection is a critical feature of every Surface Plasmon Resonance (SPR) assay. From initial design and development to data acquisition and analysis, overall data integrity is influenced by initial sensor chip selection.

Octet® Protein L (ProL) Biosensors are designed for rapid and direct quantitation of a broad set of kappa light chain containing IgG proteins, including whole molecules, FAb fragments and single chain variable fragments, in buffer or complex matrices. Octet® ProL Biosensors are offered in a tray format. Each tray contains 96 biosensors.

Monitor the effectiveness of TNF alpha inhibitors adalimumab, infliximab, and etanercept with one automated, cost-effective, and easily accessible assay.

A compact solution designed for efficient microbial colony picking, suitable for smaller labs or specific applications.