Drug discovery > Lead Discovery Products & Reviews

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Identification and optimization of the chemical, series of chemicals or bio-molecule that will interact with the target using impartial, expert opinion about the best equipment, services and the latest techniques

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Lightning-Link™ Atto 611 kit

Innova Biosciences Ltd.

Say goodbye to secondary antibodies – Go direct using the World’s Easiest DIY Antibody Labeling Kit - Lightning-Link™! • Eliminates need for secondary antibodies • Reduces the number of wash steps • Ideal for multi-protein analysis – with over 40 available labels • Very easy to use • 100% antibody recovery Lightning-Link™ kits The DIY Lightning-Link™ kit allows you to label an antibody with minimal hands-on time - less than 30…

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Lightning-Link™ Atto 633 kit

Innova Biosciences Ltd.

Say goodbye to secondary antibodies – Go direct using the World’s Easiest DIY Antibody Labeling Kit - Lightning-Link™! • Eliminates need for secondary antibodies • Reduces the number of wash steps • Ideal for multi-protein analysis – with over 40 available labels • Very easy to use • 100% antibody recovery Lightning-Link™ kits The DIY Lightning-Link™ kit allows you to label an antibody with minimal hands-on time - less than 30…

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Lightning-Link™ Atto 655 kit

Innova Biosciences Ltd.

Say goodbye to secondary antibodies – Go direct using the World’s Easiest DIY Antibody Labeling Kit - Lightning-Link™! • Eliminates need for secondary antibodies • Reduces the number of wash steps • Ideal for multi-protein analysis – with over 40 available labels • Very easy to use • 100% antibody recovery Lightning-Link™ kits The DIY Lightning-Link™ kit allows you to label an antibody with minimal hands-on time - less than 30…

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Lightning-Link™ Atto 700 kit

Innova Biosciences Ltd.

Say goodbye to secondary antibodies – Go direct using the World’s Easiest DIY Antibody Labeling Kit - Lightning-Link™! • Eliminates need for secondary antibodies • Reduces the number of wash steps • Ideal for multi-protein analysis – with over 40 available labels • Very easy to use • 100% antibody recovery Lightning-Link™ kits The DIY Lightning-Link™ kit allows you to label an antibody with minimal hands-on time - less than 30…

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Lightning-Link™ Biotin kit (Type A)

Innova Biosciences Ltd.

Say goodbye to secondary antibodies – Go direct using the World’s Easiest DIY Antibody Labeling Kit - Lightning-Link™! • Eliminates need for secondary antibodies • Reduces the number of wash steps • Ideal for multi-protein analysis – with over 40 available labels • Very easy to use • 100% antibody recovery Lightning-Link™ kits The DIY Lightning-Link™ kit allows you to label an antibody with minimal hands-on time - less than 30…

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Shamrock 500 Spectrographs

Oxford Instruments Andor

The Andor Shamrock SR-500i imaging platform is the latest addition of the Andor family of spectrographs based on Czerny-Turner optical design. The optimized optical design provides exceptional performance for multi-track Spectroscopy.The Shamrock 500i is available as a pre-aligned, pre-calibrated camera/spectrometer detection solution allowing for seamless integration in user set-up. The Spectroscopy-dedicated software interfa…

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GPCR dimer assays with Tag-lite® technology

Cisbio Bioassays

G-Protein Coupled Receptors (GPCRs) are common drug targets. Previously, most studies were based on the monomeric model, but this perception of GPCRs is now evolving towards homodimeric , heterodimeric and oligomeric models. To facilitate research into GPCR dimers, CisBio Bioassays has applied the Tag-lite® technology to GPCR interaction assays. Based on HTRF® technology, plasmids have been designed to express either the SNA…

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GPCR ligand binding with Tag-lite technology

Cisbio Bioassays

Cisbio Bioassays offer a comprehensive cellular platform to develop HTRF® ligand binding assays.Features: • Single technology and cellular platform for all GPCR assays • Unique non-radioactive ligand binding assays • Miniaturization down to < 10µl • Peptidic and non-peptidic fluorescent ligands • High Specific Binding • Low Non-Specific Binding with HTRF technology Tag-lite fluorescent ligands available for (Feb10): Vasopre…

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Tag-lite® cell-lines and reagents, a multimodal environment streamlined for GPCR studies

Cisbio Bioassays

Tag-lite® cell-lines and reagents, a multimodal environment streamlined for GPCR studies. Cellular trans-membrane receptors are high potential therapeutic targets in pharmacological research, among them G-Protein Coupled Receptors (GPCRs). To reach a better physiological understanding, their study is deepening and is now focusing on structural assessments (ligand binding, dimerisation) and also on multiple signal pathway assa…

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DIVERSet Diversity Libraries

ChemBridge Corporation

Structurally diverse small molecule libraries with broad 3D pharmacophore coverage for hit identification ChemBridge offers two, complementary DIVERSet™ Libraries, each composed of 50,000 leadlike and druglike compounds. Both DIVERSet Libraries (the DIVERSet-EXP and the DIVERSet-CL) are designed to provide the greatest coverage of pharmacophore space within 50,000 compounds while maintaining chemical structure diversity. Th…

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NimbleGen Gene Expression Microarray

Roche

Roche NimbleGen provides a unique combination of high-density arrays, long-oligo probes, and flexible design capability that together provide superior results for advanced gene expression analysis. NimbleGen microarrays enable accurate, sensitive, and specific interrogation of genome-wide expression for any sequenced and annotated genome. Researchers also can tile through a genome at any desired spacing to discover genome-wide…

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Agilent Drug Discovery Services: HTS

Agilent’s contract Lead Discovery Service utilizes label-free RapidFire technology for direct quantitation of a wide range of native analytes across diverse therapeutic areas. Supports SAR programs via retesting of hits. Uses your existing assays or RapidFire custom-developed assays. Quick data turnaround for faster drug discovery decisions.Screened as singletons or compressed format The ideal candidate assays are often the sa…

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CBC’s Next-Gen Sequencing Services

febit holding GmbH

The introduction of NGS technologies into the market has changed the way we think about scientific approaches in basic, translational and clinical research. The development of NGS applications is a rapidly evolving field – making for exciting times in genomic studies. The ability to produce large numbers of readouts at low cost makes NGS platforms useful for many applications. Next-generation sequencing applications include:•…

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AVANCE 1000

Bruker BioSpin launches a breakthrough one Gigahertz Ultra-High Field AVANCE 1000 MHz NMR spectrometer. Incorporating a record-breaking 23.5 Tesla standard-bore (54 mm) superconducting NMR magnet, the AVANCE 1000 MHz NMR spectrometer, brings one Gigahertz technology to NMR research. AVANCE 1000 MHz NMR Spectrometer with the first 1 GHz CryoProbe installedThe high field strength and high field stability in combination with the…

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