Drug discovery > Lead Discovery Products & Reviews

Purospher® STAR NH2 is a high purity aminopropyl modified stationary phase.

Purospher® STAR RP-18 endcapped is a versatile high purity reversed phase column increasing the productivity in HPLC. Purospher® STAR RP-18 endcapped provide the power to separate the most difficult of compound mixtures. With up to 150.000 N/m for 3 µm and 100.000 N/m for 5 µm particle size, Purospher® STAR RP-18 endcapped will ensure good base line separations.

SCP Science DigiSEP Blue SPE Cartridges A general purpose, single use, cation removal cartridge. DigiSEP Blue from SCP Science is a highly selective exchange cartridge is ideal for retaining transition metals in samples that contain high concentrations of potassium and sodium as in sea water. DigiSEP Blue has an aminodiacetate group that acts as a chelating agent to a variety of metallic ations in solution providing a mean t…

SCOPE, Structure-based compound optimization prioritization and evolution is an innovation from VLife to overcome challenges in lead optimization. SCOPE provides the user a way to address known problems like poor correlation between energy and activity, insensitive docking scoring functions for molecule prioritization and insufficient clues in ligand design for improvement in activity. SCOPE smartly understands the information…

Purospher® STAR RP-8 endcapped is a versatile high purity reversed phase column increasing the productivity in HPLC.Purospher® STAR RP-8 endcapped provide the power to separate the most difficult of compound mixtures. With up to 150.000 N/m for 3 µm and 100.000 N/m for 5 µm particle size, Purospher® STAR RP-8 endcapped will ensure good base line separations.

AcroPrep™ Advance filter plates are the newest edition to Pall’s filter plate family. New sealing technology and advanced tip design make these the first choice in critical sample prep applications.   Aplications: Lysate Clearance DNA purification Protein purification Multiplex assays Aqueous filtration Particulate removal Size exclusion Bead-based assays Neonatal screening Flow cytometry S…

AcroPrep™ Advance Filter Plates for Ultrafiltration Provides rapid, efficient separation of biomolecules. Omega™ membrane provides high recovery and typically results in > 90% recovery of target biomolecules. New well design results in faster, more uniform filtration rates across the plate with reduced hold-up volume for maximum sample recovery Intrinsic plate and membrane properties prevent target molecules from binding to th…

A “Brush-type” phase with broad applicability for separation of enantiomers: Whelk-O 1 is a reliable chiral HPLC column of high solvent stability and broad applicability. Whelk-O 1 is a “brush-type” phase according to the concept of Pirkle with (3R, 4R)-4-(3,5-dinitrobenzamido)-1,2,3,4-tetrahydrophen-anthren or (3S, 4S)-4-(3,5-dinitrobenzamido)-1,2,3,4-tetrahydrophen-anthren as chiral selector with high enantoselectivity for a…

High recovery sample preparation for drug analysis and screening: LiChrolut® TSC is a selective and efficient solid phase extraction sorbent designed for clean-up of pharmaceutical products and drugs obtained from blood, plasma and urine. LiChrolut® TSC belongs to the family of the so-called “mixed-mode phases”. The combination of a reversed-phase and a cation exchange mechanism gives rise to retention of the analyte on the st…

For reproducible sample preparation: LiChrolut® CN and NH2 are medium polar phases for solid phase extraction, which produces excellent reproducibility of sample preparation. This results a combination of high chemical stability and guaranteed capacity. LiChrolut® CN and NH2 are suitable for both polar and non-polar extractions. These medium polar phases have, in addition to a short-chained propyl-spacer, a polar functional gr…

Human Cav2.2/β3/α2δ calcium ion channel-expressing, stable replicating cell line (CHO-K1). Cat#: CT6159. Cryopreserved cells, 3 vials: 2x10E6 cells/vial. Platform validation: PatchXpress® , QPatch HT™ , FLIPR®

Human Nav1.8/b3 sodium ion channel-expressing, stable replicating cell line (CHO-K1). Cat#: CT6011. Cryopreserved cells, 3 vials: 2x10E6 cells/vial. Platform validation: PatchXpress® , QPatch HT™ , IonWorks Quattro®

Human a3/β4 Nicotinic Acetylcholine Receptor-expressing, stable replicating cell line (CHO-K1). Cat#: CT6021. Cryopreserved cells, 6x10E6 cells/vial. Platform validation: QPatch HT™

Human GABAA (α5β2γ2) Receptor-expressing, stable replicating cell line (CHO-K1). Cat#: CT6119. Cryopreserved cells, 3 vials: 2x10E6 cells/vial. Platform validation: FLIPR®

Human GABAA (a5β2γ2) Receptor-expressing, stable replicating cell line (CHO-K1). Cat#: CT6119. Cryopreserved cells, 3 vials: 2x10E6 cells/vial. Platform validation: FLIPR®

Human Cav2.2/b3/a2d calcium ion channel-expressing, stable replicating cell line (CHO-K1). Cat#: CT6159. Cryopreserved cells, 3 vials: 2x10E6 cells/vial. Platform validation: PatchXpress® , QPatch HT™ , FLIPR®

Human Cav2.1/b4/a2d calcium ion channel-expressing, stable replicating cell line (CHO-K1). Cat#: CT6196. Cryopreserved cells, 3 vials: 2x10E6 cells/vial. Platform validation: PatchXpress® , QPatch HT™

Human GABAA (α3/β2/γ2) Receptor-expressing, transiently transfected cells (HEK293). Cat#: CT7022. Cryopreserved cells, 6x10E6 cells/vial. Platform validation: PatchXpress®, FLIPR®

Human a7 Nicotinic Acetylcholine Receptor-expressing, stable replicating cell line (CHO-K1). Cat#: CT6201. Cryopreserved cells, 3 vials: 2x10E6 cells/vial. Platform validation: QPatch HT™ , FLIPR®

Human Cav2.1/β4/α2δ calcium ion channel-expressing, stable replicating cell line (CHO-K1). Cat#: CT6196. Cryopreserved cells, 3 vials: 2x10E6 cells/vial. Platform validation: PatchXpress® , QPatch HT™

Human Nav1.8/β3 ion channel-expressing, division-arrested cells (CHO-K1). Cat#: CT4011. Three vials of Cyropreserved irradiated cells, 2x10E6 cells/vial (6x10E6 cells total). Platform validation: PatchXpress®

Human α3/β4 Nicotinic Receptor-expressing, division-arrested cells (CHO-K1). Cat#: CT4021. Cryopreserved irradiated cells, 6 million cells per vial.. Platform validation: FlexStation III

Highest capacity for solid phase extraction: LiChrolut® EN saves time and money in solid-phase extraction as less time is required for conditioning and drying. In addition, only a little solvent is required for elution of the analytes from the cartridge bed. The reduced quantity of solvent leads to a lower degree of contamination and to an increase in detection sensitivity. This improves the analysis of the relevant extracted…

Human GABAA (α5/β2/γ2) ion channel-expressing, division-arrested cells (CHO-K1). Cat#: CT4119. Cryopreserved irradiated cells, 6 million cells per vial.. Platform validation: FlexStation III

Human GABAA (a5/b2/g2) ion channel-expressing, division-arrested cells (CHO-K1). Cat#: CT4119. Cryopreserved irradiated cells, 6 million cells per vial.. Platform validation: FlexStation III