Drug discovery > Lead Discovery Products & Reviews

  Pre-plated selection from ChemBridge's EXPRESS-Pick Collection screening compound stock.  

  Ion channel-directed selection from ChemBridge's EXPRESS-Pick Collection screening compound stock.  

  GPCR-targeted compounds based on beta-turn mimetic scaffolds designed by ChemBridge.  

  Kinase-directed selection from ChemBridge's EXPRESS-Pick Collection screening compound stock.  

  Kinase-directed selection from ChemBridge's CORE Library screening compound stock.  

Roche NimbleGen provides a unique combination of high-density arrays, long-oligo probes, and flexible design capability that together provide superior results for advanced gene expression analysis. NimbleGen microarrays enable accurate, sensitive, and specific interrogation of genome-wide expression for any sequenced and annotated genome. Researchers also can tile through a genome at any desired spacing to discover genome-wide…

Agilent’s contract Lead Discovery Service utilizes label-free RapidFire technology for direct quantitation of a wide range of native analytes across diverse therapeutic areas. Supports SAR programs via retesting of hits. Uses your existing assays or RapidFire custom-developed assays. Quick data turnaround for faster drug discovery decisions.Screened as singletons or compressed format The ideal candidate assays are often the sa…

The universal grinder for every application

Everything you need for sieving

The most precise way of sample division

Feature uniform skirt heights for greater robotic gripping surface Solvent resistant polypropylene provides compatibility with many common organic solvents (e.g., DMSO, ethanol, methanol) DNase- and RNase-free Total volume is 360 µL; recommended working well volume is 75 to 200 µL Without lids; lids, sealing mats and tapes supplied separately

The introduction of NGS technologies into the market has changed the way we think about scientific approaches in basic, translational and clinical research. The development of NGS applications is a rapidly evolving field – making for exciting times in genomic studies. The ability to produce large numbers of readouts at low cost makes NGS platforms useful for many applications. Next-generation sequencing applications include:•…

Bruker BioSpin launches a breakthrough one Gigahertz Ultra-High Field AVANCE 1000 MHz NMR spectrometer. Incorporating a record-breaking 23.5 Tesla standard-bore (54 mm) superconducting NMR magnet, the AVANCE 1000 MHz NMR spectrometer, brings one Gigahertz technology to NMR research. AVANCE 1000 MHz NMR Spectrometer with the first 1 GHz CryoProbe installedThe high field strength and high field stability in combination with the…

CYTOOplates are optical grade, glass-bottom microplates in 96 or 384-well format with black-side upper structures for fluorescence applications offering reduced background and minimum scattered light. Each well holds an array of over 4,000 (96-well) or 1,000 (384-well) identical micropatterns. CYTOOplates are compatible with your High Content Screening equipment.

The CYTOOchamber™ is a 35mm footprint device specially designed and manufactured for the 2x2cm² square CYTOOchip™ format which enables you to do high resolution timelapse microscopy. The CYTOOchamber uses a patented magnetic system for easy assembly. The CYTOOchamber has the same footprint as standard 35mm culture dishes and therefore will fit into all 35mm microscope stage adaptors. Components: • 1 bottom plate • 1 upper mai…

SCOPE OF APPLICATION ASEPTIC FILLING • Pharmaceutical • Diagnostic • Biopharmaceutical • Disposable filling • Aseptic liquid filling • Peristaltic liquid filling • No cleaning validation • Easy product change-over • Ideal for small batch production • No cross contamination • High accuracy filling VERY COMPACT Machine dimensions are 1.13 x 2.05 m, i.e. FMB210 takes up very little space in a cleanroom. SHORT CHANGE OVER TIME Ide…

The MS-3 laser scanner offers the fastest read performance in embedded compact bar code scanners. The wide scan angle of 70 degrees is coupled with ultra-compact size and flexible mounting. • Decodes/second: up to 1000 • Read Range: 2 to 10” (51 to 254 mm) • Wide Scan Angle • IP54 Enclosure High performance and flexibility make the MS-3 the optimal choice for reliable reading in embedded instruments. Compact & Lightweight: The…

The NorDiag Bullet instrument is CE IVD ready and provides TRUE walk away automated sample preparation for molecular diagnostics. The NorDiag Bullet is compact yet flexible, designed to provied targetend solutions for the user's needs.

USP Apparatus 4 Product Details:• Cells designed for MR, CR and ER tablets, capsules, suppositories, powders, pellets, APIs, implants, medical devices, ophtalmic devices, drug eluting stents, creams, gels, suspensions, microspheres, liposomes and nanospheres • Suitable for R&D and QC, manual and automated sampling, firmware or software driven, linked to UV, UVFO (UV Fiber Optic) and fraction collector for HPLC • Evolution of t…

• One of the most advanced power meters in the market • Using state-of-the-art analog board for superb sensitivity, accuracy, and speed • Power measurement capable of 11 fW – 20 kW • Energy measurement capable of 7 µJ – 20 kJ • Measurement rep-rates up to 10 kHz • Sampling rate up to 250 kHz

UHPLC quaternary solvent delivery system with operating pressure to 1250 barThe Thermo Scientific Accela high-speed chromatographic system provides fast, efficient HPLC and U-HPLC in One Efficient, Limitless System. The Accela™ 1250 High Speed LC pump provides accurate and precise flow and gradients under all operating conditions with minimum pulsation. Features of the UHPLC Accela 1250 pump: • Quaternary capabilities with f…

Full Spectrum Data Acquisition Fast data acquisition and superb reliability make the Thermo Scientific Evolution Array spectrophotometer the cornerstone of your complete analytical environment. Instant full-spectrum analysis, room light immunity, and a complete line of accessories deliver simplicity and capability that is second to none. Photodiode array technology allows you to acquire full-spectrum UV-Visible data almost i…

Universal Caps - Seal multiple size tubes with one size cap. Easy to use, polyethylene caps feature a universal fit. Seal caps with one handed use. Caps provide tight, leak-proof seal for standard glass or plastic tubes. The innovative design of the Heathrow Scientific Universal Caps fit larger tube sizes inverted and smaller tube sizes upright. Compatible with tube sizes 10 mm, 12/13 mm or 16 mm. Available in Blue, Green, Red…

Evaluate compounds in human stem cell-derived, ventricular-type cardiomyocytes. Effects on action potential parameters are evaluated in single human cardiomyocytes using patch-clamp recording Benefits: Human ion channels expressed in a native cardiac environment Detects AP Prolongation (QT risk) and EADs (Torsade trigger) Stable recordings at physiological temperature with minimal diffusion delays Cost-effective Ra…

The InviGenius provides advanced and reliable performance in automated nucleic acid sample preparation in combination with the well established magnetic bead based InviMag technology for DNA and RNA purification – especially for increased standardization and streamlined laboratory workflows. Innovative functions and optimized protocols enable reliable results of high quality. The InviGenius automated system, with built-in touc…