Drug discovery > Lead Discovery Products & Reviews

Over 50 years of reproducible performance

Semi-preparative Columns with excellent batch-to-batch reproducibility

Polynuclear Aromatic Hydorcarbons (PAHs) are among the most frequently monitored environmental contaminants. Waters PAH columns are optimized for the HPLC analysis of PAHs. These columns achieve baseline resolution and excellent peak symmetry for 16 different target analytes in less than 25 minutes, while employing a simple water/acetonitrile binary gradient method. The resolving power of the PAH columns provides superior pe…

The popular Bondapak® C18 chemistry and Porasil® silica packing material are available in three different particle sizes, 10, 15-20, 37-55 micron, providing easy transfer of chromatography methodology from one particle size to another. You can utilize your existing 10 micron Bondapak or Porasil chromatography as a starting point for scale-up or, if you are developing a new purification protocol, investigate which preparative…

These columns provide accurate and precise molecular weight calculations in under 7 minutes! - Fast, accurate and precise molecular weight determinations - Increase sample throughput - Greatly decrease solvent consumption and disposal

The Envirogel high-efficiency GPC cleanup columns are specifically designed to remove low volatility, high molecular weight interferences, such as lipids and natural resins, from environmental samples as specified in EPA Method 3640A. In the past, the cleanup procedure for environmental samples was performed on low-efficiency GPC columns based on packing particle diameters of 37-75 micron (200 to 400 mesh) Bio-Beads S-X resins…

For applications where the sample is neither volume or concentration limited, Waters offers 1 and 2mm Internal Diameter columns of various lengths for use on traditional HPLC MS inlets.As with Waters array of NanoEase™ columns, the same Waters reversed-phase packings are also available in these two column internal diameter offerings. Chemistry choices include: XBridge® Columns, CORTECS® Columns, XSelect Columns, Atlantis® Pola…

MassPREP™ On-Line Desalting Cartridges are an effective tool for the successful desalting of acidic, basic, and large globular proteins. The overall MassPREP™ desalting strategy provides an easy, fast (< 3 minutes), and reproducible approach for the effective desalting of proteins stored in physiological salt buffers prior to high resolution ESI-MS structural analysis.

The polar organic and the polar ionic modes have become increasingly popular largely because of their ideal compatibility with MS detection and preparative LC. Two years of extensive research at Astec in understanding these mechanisms has resulted in new possibilities for extending their effectiveness even further. Important changes in linkage chemistries and the silica and the silica have now led to the new CHIROBIOTIC V2 and…

bed wt. 25 mg, volume 10 mL , (LRC), pk of 50 Application A class selective MIP phase for the multi-residue extraction of beta-agonists in urine, tissues, and other biological fluids. SupelMIP - Beta-agonists was developed for the selective extaction of a broad range o beta-agonists such as brombuterol, clenbuterol, formoterol, isoxuprine, mapenterol, ractopamine, ritrodine, salbutamol, salmeterol, terbutaline, tulobuterol, zi…

In 2008 Gentronix launches a new S9 protocol to extend the application of the GreenScreen HC assay to include the detection of genotoxic metabolites. Many pharmaceuticals only present a genotoxicity hazard after metabolism and such chemicals are called pro-mutagens or pro-genotoxins. Generally, although not exclusively, the liver is considered responsible for the “metabolic activation” (MA) of promutagens. However, none of t…

The DE Midi range of High Performance CCC (HPCCC) equipment is based on traditional liquid/liquid partitioning and extends the purification options available to chemists, primarily in Development, who are looking purify samples from 5 grams to 1,000 grams of material. The equipment is easily connected and interfaced into existing LC equipment and provides options when existing solid phase technology cannot obtain the resolutio…

Complete range of high quality cuvettes for use in optical spectroscopy Kromatek now has a range of excellent low cost cuvettes manufactured from high purity silica and manufactured to ISO 9000. Optical transparency is guaranteed as is matching if buying sets of cuvettes.The Kromatek cuvettes are extremely competitively priced! And we have optical glass cuvettes for colorimetry and general teaching applications UV-Visib…

The Model 307 Oxidizer utilizes the patented "open/close" flame oxidation technology. The result: an oxidizer that will expand your experimental designs in liquid scintillation counting.

Scaling up is easier when using an HPLC media that provides near identical performance across all particle sizes and with increases in column diameter. The separation characteristics of each Phenomenex media offer unique selectivity for each type of application and significant production gains for maximum loadability and process economy. Achieve identical performance from analytical development to large process scale. Our Luna…

SCAT solvent safety systems have been designed to bring solvent safety to the laboratory. The specially designed caps for both solvent reservoirs and waste containers fit virtually any sized container. Certified by TUV in Germany these safety systems af guaranteed to protect your health in the laboratory. Recent legislation has meant the use of solvent safety systems are mandatory in a number of EU countries and several EU m…

FineView precision microplates for observing and measuring cell growth A range of precision microplates and cell culture plates with different materials for growing and observing cells. A new polymer film not only helps in the groth of cell cultures, but also allows better optical transmission for observing and measurement using spectrometers and plate readers A variety of culture plates including: Polymer film Glass…

With a fresh and customer focussed approach to Polymer Analysis, PSS is Germany's leading authority in Gel Permeation Chromatography, GPC and SEC. The most comprehensive range of products for standards, columns instruments and software coupled with more than twenty years experience in delivering customer oriented results. A complete range of standards for organic and aqueous GPC Columns for organic separations Columns f…

ELSD detectors - 3 models to choose from Model 100 ELSD – Simple OperationModel 300S ELSD – Advanced ControlModel 400 ELSD – Sophisticated Sytem Management Highest dynamic range 4.5 orders of magnitude Equal response between analytes High sensitivity even for semi-volatiles Independantly control the temperature of the nebuliser and drift tube

AZUR 4.0 The latest version of chromatography data system for stand-alone acquisition and analysis. Many new features including enhanced reporting capabilities and the new 24 bit USB interface. USB or PCI interface up to 4 independant channels Simple user interface Advanced functionality Low cost academic version

Fluorovette™ as a replacement to low volume quartz-silica cells. The incredibly low cost makes them disposable which is great for assays which require maximum sensitivity down to 2nM detection limit and zero carryover between measurements. Avoids trapping air bubbles due to unique composite design UV Transparent down to 220nm Sample volume: 50 uL Pathlength: 0.75 mm Dead Volume in channels: 1 uL for the inlet channe…

The Biologic stopped-flow SFM-400 and Quench-flow QFM-400 are considered to be the benchmarks. rapid kinetics stopped flow analysis  From simple SFM-20 2 channel to 5 channels with quench flow Perform double mixing experiments with control over delay time and mixing time Independent stepper motor control of each syringe gives you total control Full software control with optional Biokine software for quality data processi…

For spectral recording in UV/Vis spectroscopic modes. MOS-450/AF for absorbance and fluorescence modes. This includes a dual illumination monochromator and single-channel detection. MOS-450/AF-CD for absorbance, fluorescence, fluorescence anisotropy and circular dichroism modes. This includes the same hardware as the /AF version, with in addition : polarizing optics, photoelastic modulator and synchronous signal detectio…

Proteema is the right choice for the separation of all kinds of biomolecules including proteins and gelatines. The columns are silica based and can be used with eluents up to a pH value of 7. If the application requires separations at higher pH in more ‘basic’ eluents, PSS SUPREMA a polymer based material is recommended. Generally the pore-size distribution of silica based columns is smaller than that of polymeric columns, whi…

1 to 8 channels online vacuum degasser Low cost replacement degassing units to replace broken units or helium sparging. You can easily improve chromatography by degassing solvents. Three ranges in one! Degasys - low cost unit with options for prep HPLC Degasys Populaire - routing unit of choice for most applications Degasys Ultimate - high quality unit most often used for low volume HPLC Low cost  Degasys degassers…