Drug discovery > Lead Discovery Products & Reviews

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ACQUITY UPLC® BEH Phenyl columns utilize a trifunctional C6 alkyl tether between the phenyl ring and the silyl functionality. This ligand, combined with the same proprietary endcapping processes as the ACQUITY UPLC™ BEH C18 and C8 columns, provides ultra-low column bleed, long column lifetimes and excellent peak shape. This unique combination of ligand and endcap on the 1.7 μm BEH particle creates a new dimension in selectivi…

Waters offers a broad range of vials, each one is held to tight dimensional tolerances and the certified products have cleanliness measured by LC and MS.LC/GC Certified vials are tested by LC/UV for residues of chemicals used in processing and packaging vials. The septa are tested by headspace GC to ensure low levels of low molecular weight polymer. These vials are suited for analyte concentration in the µg/mL concentration; t…

The Waters IdentityE High Definition Proteomics system defines the new standard for rigorous protein identification. The IdentityE High Definition Proteomics System is an UltraPerformance LC® (UPLC)/High-Bandwidth Mass Spectrometry (MS E) system solution suitable for confident protein identification designed to meet stringent requirements as outlined by leading scientific journals.The new Waters IdentityE High Definition Pro…

The new Guava Nexin® reagent monitors induction of apoptosis quickly and easily, with minimal chance for contamination. Annexin V is a calcium-dependent phospholipid binding protein with high affinity for phosphatidylserine (PS), a membrane component normally localized to the internal face of the cell membrane. Early in the apoptotic pathway, molecules of PS are translocated to the outer surface of the cell membrane where Ann…

Millipore's full-length mTOR kinase is now available as part of the KinaseProfiler™ Service. This kinase is the first biologically relevant mTOR to be commercially available. The KinaseProfiler Service offers 264 kinases for selectivity profiling, using a catalytic radiometric assay format. The addition of the full-length mTOR to the KinaseProfiler panel provides high-quality, confidential screening of compounds against this c…

The Picovitro plates are optimal diagnostic tools for studying thousands of individual living cells in real time, applicable on both adherent and non-adherent cells for short-term (72 hours) or long-term (10-14 days) analysis. This MicroTiter plate format is available with 3243 wells. It is compatible with standard instruments, e.g., flow cytometer with sorting capabilities.

The Picovitro plates are optimal diagnostic tools for studying thousands of individual living cells in real time, applicable on both adherent and non-adherent cells for short-term (72 hours) or long-term (10-14 days) analysis. This MicroArray format is available with 672 wells. It is compatible with standard instruments, e.g., flow cytometer with sorting capabilities.

Aitken Scientific have created a software product called A-S Login (fully validated to GAMP standards) which will enable the pharmaceutical industry and its suppliers to minimise cost and time when implementing the requirements of 21 CFR Part 11.     • Maintains permitted applications, allowing versions and access rights to be controlled.     • Maintains the list of authorised users             o Password administration…

ACTOR™ (Automated crystal transport orientation and retrieval robot) is a proven commercial solution for automating routine crystal screening and data collection at both synchrotron beam lines and home laboratories. Compatible with almost any goniometer and detector combination, the ACTOR eliminates much of the physical handling of samples required during crystal screening and data collection. ACTOR allows you to screen up to…

ApplicationSamples suitable for the Caspase 3 Activity Assay are: Lysates of apoptosis-induced cells Recombinant caspase 3 (CPP32) The Caspase 3 Activity Assay can be used to: Detect and quantify in vitro caspase 3 activity in cell lysates Analyze caspase 1, 2, 3, or 7 activity by simply omitting the capture-antibody step Perform inhibitor studies for Caspase 3 This kit is intended as a tool for life science…

This family of kits provides ultra-sensitive, non-radioactive quantitation of cyclic adenosine monophosphate (cAMP) in cell lysates. - Accuratelly detect less than 60 femtomoles of cyclic adenosine monophosphate (cAMP) in cell lysates. - Grow cells and run the assay in the same plate, eliminating loss of cell lysates from transferring (cAMP-Screen Direct™ System only). - Reduce interference from test compounds and improve CVs…

The NA-Star® Influenza Neuraminidase Inhibitor Resistance Detection Kit includes everything you need to quantitate neuraminidase activity and neuraminidase inhibitor resistance in avian, equine, human (types A and B), and porcine influenza viruses. The kit's fast and easy protocol and convenient 96-well plate format make it ideal for monitoring influenza virus neuraminidase inhibitor resistance, as well as high-throughput inhi…

The FTS ThermoJetTM & AirJet® XE systems deliver a stream of precisely controlled hot or cold air that can can be used for testing components, hybrids, modules, PCBs, and assemblies at temperature. The AirJet can also be used to cycle temperatures and is an ideal tool for a materials R&D laboratory. Air temperatures range from -80°C to +225°C, depending upon model. A special model, the XR exists for cooling test samples for NM…

Dual-Light® luminescent reporter gene assay is designed for the rapid and sensitive detection of firefly luciferase and b-galactosidase in a single extract aliquot for gene expression assays. Detection of firefly luciferase and b-galactosidase in the same sample simplifies normalization of transfection efficiency Wide dynamic range of b-galactosidase and luciferase assays enables accurate measurement of both enzymes from…

The Galacto-Light Plus™ beta-Galactosidase Reporter Gene Assay System is designed for the rapid, ultrasensitive detection of b-galactosidase in reporter gene assays.

The Gal-Screen® assay system combines direct cell lysis with rapid, ultra-sensitive chemiluminescent detection of β-galactosidase reporter enzyme.

The Luc-Screen® assay system with extended-glow light emission is designed for sensitive detection of firefly luciferase reporter enzyme.

Recombinant Human IFN Alpha Sampler, 12 individual subtypes including: Human IFN-alpha A, B2, C, D, F, G, H2, I, J1, K, 4b, WA Catalog Number: 11001-1 Activity: Request Info Source: E. Coli  Accession Number: Request info Size: 1 kit Purity: ≥ 95% Formulation: Frozen with a carrier protein Protein Synonyms: IFN, Interferon, Type I Interferon, Sampler, SubtypeShipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Pre…

Recombinant Human IFN Alpha A (Alpha 2a), Gene IFNA2 Catalog Number: 11100-1 Activity: 8.7 x 108 u/mgSource: E. Coli Accession Number: V00549Size: 5 x 106 unitsPurity: ≥ 95% Formulation: Frozen with a carrier protein Protein Synonyms: IFN, Interferon, Type I Interferon, Subtype Shipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Preservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effectiv…

Recombinant Human IFN Alpha A (Alpha 2a), Gene IFNA2 Catalog Number: 11101-2 Activity: 8.7 x 108 u/mg Source: E. Coli Accession Number: V00549 Size: 20 µg Purity: ≥ 95% Formulation: Frozen without a carrier protein Protein Synonyms: IFN, Interferon, Type I Interferon,Subtype Shipping Conditions: Dry ice Storage Temp.: -20˚C/-70°CPreservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effective 10/1/2007):…

Recombinant Human IFN Alpha 2 (Alpha 2b), Gene IFNA2 Catalog Number: 11105-1 Activity: 1.7 x 108 u/mg Source: E. Coli Accession Number: V00548 Size: 1 x 105 units Purity: ≥ 95% Formulation: Frozen with a carrier protein Protein Synonyms: IFN, Interferon, Type I Interferon, Subtype Shipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Preservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effective 10/1…

Recombinant Human IFN Alpha B2 (Alpha 8), Gene IFNA8 Catalog Number: 11115-1 Activity: 4.6 x 108 u/mg Source: E. Coli Accession Number: X03125  Size: 1 x 105 units Purity: ≥ 95% Formulation: Frozen with a carrier protein Protein Synonyms: IFN, Interferon, Type I Interferon, Subtype Shipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Preservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effective 1…

Recombinant Human IFN Alpha C (Alpha 10), Gene IFNA10 Catalog Number: 11120-1 Activity: 2.3 x 108 u/mg Source: E. Coli Accession Number: X02961 Size: 1 x 105 units Purity: ≥ 95% Formulation: Frozen with a carrier protein Protein Synonyms: IFN, Interferon, Type I Interferon, Subtype Shipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Preservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effective 10/…

Recombinant Human IFN Alpha D (Alpha 1 [Val 114]), Gene IFNA1 Catalog Number: 11125-1 Activity: 7.5 x 107 u/mg Source: E. Coli Accession Number: V00538 Size: 1 x 105 units Purity: ≥ 95% Formulation: Frozen with a carrier proteinProtein Synonyms: IFN, Interferon, Type I Interferon, Subtype Shipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Preservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effect…