Drug discovery > Lead Discovery Products & Reviews

Note: License Description - PLT,96WL,STRIPWELL,1X8,HIGH BI May be used in a variety of laboratory assays Flat bottom strips are designed to easily break apart and are pre-assembled in an style strip holder that allows each individual well to be positioned back into the plate once broken High binding surface binds medium (>10kD) and large biomolecules that possess ionic groups and/or hydrophobic regions. Binding capacity is…

Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the immobilization of large molecules, such as antibodies, that have large hydrophobic regions that can interact with the surface Binding capacity of approximately 250 ng of mouse IgG/cm2 EIA/RIA plates are tested on lot-to-lot basis and the certification results for ea…

Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the immobilization of large molecules, such as antibodies, that have large hydrophobic regions that can interact with the surface Untreated microplates have a binding capacity of approximately 100 to 200ng IgG/cm2 Recommended working volume of up to 75 to 200 µL Confor…

Flat bottoms Nonreversible lids with condensation rings to reduce contamination Individual alphanumerical codes for well identification Uniform footprint for ease in stacking Treated for optimal cell attachment Sterilized by gamma irradiation Certified nonpyrogenic

Flat bottoms with 360 µL total volume Recommended working volumes of 75 to 200 µL Treated for optimal cell attachment Nonreversable lids with condensation rings to reduce contamination Sterilized by gamma radiation and certified nonpyrogenic Individual alphanumeric codes for well identification Bulk packed 20 per bag

These Costar® Spin-X® centrifuge tube filters have a 0.45 µm pore CA membrane-containing filter unit within a 500 µL capacity polypropylene microcentrifuge tube. Cellulose acetate (CA) membranes provide fast flow rates and low protein binding Ideal for removing bacteria, particles, or cells from liquids, HPLC sample preparation and DNA removal from agarose or acrylamide gels. Sterile and certified nonpyrogenic and DNase-/RN…

These Corning® syringe filters have acrylic copolymer housings, female Luer lock inlets and male Luer slip outlets. Polyethersulfone (PES) membranes provide the fastest flow rates, low protein binding and low extractables 100% integrity tested, sterile and certified nonpyrogenic and noncytotoxic Manufactured in accordance with ISO 9001 standards

Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the immobilization of large molecules, such as antibodies, that have large hydrophobic regions that can interact with the surface Untreated microplates have a binding capacity of approximately 100 to 200ng IgG/cm² Without lids, lids supplied separately Total volume is…

Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the immobilization of large molecules, such as antibodies, that have large hydrophobic regions that can interact with the surface Total volume is 190 µL; recommended working volume of up to 25 to 125 µL Conforms to standard microplate footprint and dimensions Without l…

This microplate has half the growth area of a standard 96 well plate Flat bottoms with 190 µL total volume White walled plates enhance luminescent signals and have low background luminescence and fluorescence Opaque walls to prevent well-to-well crosstalk Nonreversable lids with condensation rings to reduce contamination Sterilized by gamma radiation and certified nonpyrogenic Bulk packed 20 per bag

The Direct Connection UNIGUARD allows the guard cartridge outlet to be directly placed against the analytical column inlet frit. Product detail: We recommend all analytical columns are protected by a guard cartridge, which is replaced on a regular basis. The ID of the analytical column determines the correct ID for the guard cartridge. We offer 10x1, 10x2, 10x3, 10x4mm guard cartridges in all our stationary phases to ensur…

The Javelin guard design is a one-piece format that can be installed without wrenches and requires no holder, which allows quick and easy replacement. Product detail: We recommend all analytical columns are protected by a guard column or cartridge, which is replaced on a regular basis. The ID of the analytical column determines the correct ID for the guard, so we offer 1.0, 2.1, 3.0 and 4.0 diameter Javelin guard columns in…

MultiSEP™ solid phase extraction wells from Thermo Electron offer robust and reproducible sample preparation and pre-concentration on a routine basis.Wells are available in pre-assembled plate format or as individual wells to allow customisable plates to be assembled by the user.Sorbent packings include the ever-popular silica based bonded phases and also include novel and unique chemistries for specialised applications. Multi…

HyperREZ™ columns are specially designed for analysis of organic acids, alcohols, saccharides and carbohydrates. They employ a polymeric support with ligand exchange groups. The ligand exchange resins contain highly sulfonated cation exchange resins that have Group I, Group II or transition metals associated with the chromatographic surface.HyperREZ™ columns are based upon a polymeric resin that shows stability from pH 1 to 14…

White walled plates enhance luminescent signals and have low background luminescence and fluorescence Flat bottoms with 360 µL total volume Recommended working volumes of 75 to 200 µL Treated for optimal cell attachment Without lids, lids supplied separately Sterilized by gamma radiation and nonpyrogenic Individual alphanumeric codes for well identification Bulk packed 25 per bag

BioBasic 8 Columnso   Improved reproducibility, efficiency and column lifetimeso   Range of stationary phases to optimize selectivityo   Powerful resolution, even on short column lengths Product detail:BioBasic 8 columns provide exceptional reliability for separations of proteins, peptides, and other biomolecules through a combination of high purity silica and reproducible, stable bonding.  The proprietary bonding procedure en…

BetaMax Acid Columns o   High surface area area and bonded phase coverage for maximum retention, even in high percentage organic conditionso   Chemistries for acidic compounds Product detail: For alternative selectivity to traditional alkyl phases, we recommend you try the polar embedded phase BetaMax columns. The stationary phase contains urea groups embedded within the C12 chain, which extra interactions with samples to…

BETASIL C18 Columnso   Broad range of particle sizes and phases for wide method development optionso   High surface area and phase coverage for reproducibility and sharp peak shapes Product Detail BETASIL columns are based on 100Å pore size, fully deactivated type B silica to ensure sharp peaks and excellent reproducibility for the analysis of a wide range of compounds. The 100Å pore size gives a higher concentration of statio…

BetaBasic 4 Columnso   Excellent peak shapes for basic compoundso   Superb stability at both low and high pH Product detail:BetaBasic 4 columns are based on a 150Å pore size, fully deactivated type B pure silica to ensure sharp peaks and excellent reproducibility for the analysis of basic compounds.  Due to stable bonding chemistry and excellent surface coverage, BetaBasic 4 columns show excellent peak shape for basic compound…

Hyperbond™ is a cost effective alternative to µBondapak (a trademark of Waters Corporation). It is based on an irregular silica with 10µm particle size.

o   100% porous graphitic carbon with very different selectivity to reversed-phase silica columnso   Exceptional retention of very polar compoundso   Separation of structurally similar compoundso   Stable from pH 1 to 14 at high temperatures in a wide range of solvents Product detail: Hypercarb is a unique material for HPLC manufactured by Thermo Hypersil-Keystone. Hypercarb consists of fully porous spherical carbon particle…

o  Separate hydrophobic and ionic compounds in a single runo  Select from two mixed mode phases, using either cation or anion exchange combined with C18o  Retention of compounds is optimized using mobile phase pH, ionic strength and percent organic Product detail: Hypersil Duet columns are an ideal choice for unknown compounds and metabolism studies, as they can separate hydrophobic and ionic compounds in a single analysis…

The Hypersil SAX is recommended for analysis of small organic molecules and organic acids. Product detail: Hypersil SAX is a strong anion exchange column, which is typically used for  analysis of small organic molecules and organic acids. As the columns are based on the first generation classical 120Å pore size silica they are not recommended for analysis of biomolecules. For new methods we recommend trying our latest ion…