Drug discovery > Lead Discovery Products & Reviews

SARS-CoV-2, which causes the global pandemic coronavirus disease 2019 (Covid-19), belongs to a family of viruses known as coronaviruses that are commonly comprised of four structural proteins. One of the proteins, SARS-CoV-2 Spike Protein (S Protein), is a glycoprotein that mediates membrane fusion and viral entry, and as such is a crucial COVID-19 target.  R&D Systems SARS-CoV-2 Spike range of bioactive proteins are valida…

CHO expressed. GCN4-IZ trimerization domain. Prefusion Conformation. High ACE-2 binding  

South African Variant  

UK Variant. Resistant to Furin & Stabilized Prefusion Conformation

Brazilian Variant

Time-of-flight mass spectrometers for GC and GCxGC

A synthetic, optimized SLE sorbent that improves reproducibility for your extractions when compared to traditional diatomaceous earth SLE sorbents.   

Bioinformatics and Protein Array Services

Profiling against cancer antigens. Using the CTA Protein Array, Sengenics can quantify autoantibodies against more than 200 clinically relevant cancer testis antigens. These are tumor antigens normally expressed in germ cells but not in adult somatic tissues. In cancers, this regulation can be disrupted, resulting in CTA expression in tumors. The CTA array is ideal for research related to cancer immunotherapy.

Cancer drug screening and discovery. The OncoRex p53 Cancer Array provides a biologically relevant screening tool since all p53 variants are correctly folded and functional using the patented KREX ® protein folding technology. Using the array, Sengenics can screen your therapeutic antibodies and protein binding compounds against more than 100 p53 wildtype and mutant variants by measuring their impact on DNA binding as a func…

High-throughput online automated sample concentration LC-MS solution for water and beverage analysis

Automate complex and time-consuming sample preparation workflows integrated with LC-MS analysis

Use our prepacked low-pressure chromatography columns with any chromatography system. Choose Ion Exchange, Affinity, Desalting, or patented Mixed-Mode resins.

(6aR,9R)-Δ10 -THC (CRM) (Item No. 33011) is a certified reference material that is structurally similar to known phytocannabinoids and has been found as a byproduct in Cannabis processing. It is regulated as a Schedule I compound in the United States and is provided as a DEA exempt preparation. Also available are (6aR,9S)-Δ10 -THC (CRM) (Item No. 33012), 9(R)-Δ6a,10a -THC (CRM) (Item No. 33013), and 9(S)-Δ6a,10a -THC (CRM) (I…

Looking to Replace REACH-Restricted NMP? Go Green!

Phytocannabinoid Mixture 8 (CRM) (Item No. 34043) is a certified reference material mixture that contains neutral, non-acid, forms of compounds that can be isolated from plants in the genus Cannabis.  Included are Δ9-THC, Δ8-THC, cannabinol, cannabidiol, (±)-cannabichromene, cannabidivarin, cannabigerol, and tetrahydrocannabivarin. It is provided as a DEA exempt preparation in an amber ampule in which the headspace has been p…

Melanie™ 9 is a comprehensive easy-to-use software solution for the visualization, matching, detection, quantitation, and analysis of 2D gel electrophoresis (2DE) and Western blot images.

Amersham™ brand Typhoon™ laser-scanner platform provides exceptional data quality through extremely sensitive detection, high image resolution, and a very broad linear dynamic range. These versatile imaging systems support multiple imaging modes, including phosphor imaging, red/green/blue (RGB) and long and short wavelengths of near infrared fluorescence (NIR), as well as optical densitometry (OD) of proteins in stained gels.

Aura® CL systems couples Fluorescent Membrane Microscopy and Backgrounded Membrane Imaging to help you understand what’s in your cell therapy. It detects, counts, sizes, and IDs cellular aggregates and subvisible particles and ID’s cellular from other particles without any machine learning so you can maximize the purity, safety, and efficacy of your therapeutic.

UV-Vis single beam scanning spectrophotometer

Visible touchscreen scanning spectrophotometer

Uv-Vis double beam scanning spectrophotometer

Uv-Vis double beam scanning spectrophotometer with 1nm bandpass

UV-Vis double beam scanning spectrophotometer with GMP compliancy 

UV-Vis double beam scanning spectrophotometer with variable bandpass