Drug discovery > Lead Discovery Products & Reviews

The Mass Spectrometry Primer, an 82-page paperback book, covers a wide range of topics related to the most wide spread of modern mass spectrometry practices and answers some frequently asked questions about the use and capabilities of mass spectrometers. Links are also provided to articles for more in-depth reading. The first section examines who uses mass spectrometers, followed by how compounds are ionized in the source to b…

The 515 HPLC pump is a programmable, free-standing HPLC pump available in isocratic, gradient, and semi-preparative configurations: • Precise stepper motor control (48 steps/µL resolution) of dual reciprocating pistons • Non-circular drive gears provide smooth, uniform eluent delivery • User-programmable flow rate calibration and compressibility compensation factors ensure straightforward pump operation qualification • Tests t…

The Waters 3100 Mass Detector is a compact, single-quadrupole atmospheric pressure ionization (API) mass detector that provides selectivity, sensitivity, and throughput with faster scan speeds. Designed specifically for chromatographers performing LC/MS analysis, it offers a simple yet powerful solution for multi-tasking, fast-paced laboratory environments – with robust and reliable performance, and walk-up operation for any e…

The Waters OpenLynx™ Open Access Application Manager provides walk-up access for LC/UV, LC/MS, LC/MS/MS, and GC/MS operation in laboratories whose chemists have varying levels of instrumental analysis experience. OpenLynx also provides customizable batch processing to support the large amounts of data generated by high-throughput analyses. It comes standard with MassLynx™ Software. Features of Waters OpenLynx: Easy to Learn T…

SIGIS 2 is a scanning imaging remote sensing system that allows rapid identification, quantification and visualization of gas clouds from long distances.   The system maps a predefined area and results of the analysis are visualized by a video image, overlaid by a chemical image. The SIGIS 2 is part of the equipment of emergency response forces around the world. In addition, SIGIS systems are applied in environmental app…

The EM 27 is a ruggedized remote sensing system providing high performance spectroscopy in the field. The EM 27 can easily be deployed in the field for various air monitoring applications.Emissions from smoke stacks, waste disposal and hazardous emissions from chemical accidents can be observed with an operating range of typically several kilometers. The EM 27 SUN features a solar tracker for measurements of atmospheric…

The CONFOCHECK is a dedicated FTIR system for the investigation of proteins in water. Its specific configuration facilitates a fast data acquisition (ca. 30 sec. per sample) with a high sample throughput controlled by an extremely user friendly software interface. Main applications for the CONFOCHECK are the detection and quantification of conformational changes in proteins and the protein concentration determination. Quant…

The PMA 50 module has been dedicated developed for Polarization Modulation measurements.   Both linear dichroitic measurement techniques like PM-IRRAS and circular dichroitic experiments like VCD spectroscopy can be realized using this accessory. It can be adapted to Bruker TENSOR and VERTEX FTIR spectrometers. All optic and electronic components in the PMA 50 module are optimized for the Polarization Modulation. Both…

CryoSAS is an automated high sensitivity FT-IR system for the quality control of solar and electronic grade Silicon according to international ASTM/SEMI standards.   Although sample cooling to very low temperatures is required, CryoSAS operates without cryogenic liquids, is easy to use and optimized for the requirements of industry customers. CryoSAS combines Bruker's high performance FT-IR spectrometers with bui…

Thermogravimetric analysis (TG) follows changes in mass of the sample as a function of temperature yielding information of the various component amounts. Whereby identification of gases released during thermal treatment cannot be performed just by thermal analysis. Fourier-Transform-Infrared (FTIR) spectroscopy overs an excellent solution for the identification of unknown compounds. IR, a classical technique, depends upon t…

Bruker’s microplate extension HTS-XT allows the application of FTIR spectroscopy as method for high-throughput screening. This external module can be connected to different Bruker Optics FTIR spectrometers. Depending on its configuration it can be used for measurements in the mid infrared to the near infrared and even the VIS range. The sampling plates for the IR analysis correspond to the standardized 96- or 384-well mi…

New line of standard and low-profile PCR plates for improved PCR efficiency.   Improve PCR efficiency with a new line of PCR plates manufactured with the best raw materials using the latest in production technologies. Standard and low profile PCR plates in clear and white are suitable for use in most thermal cyclers. These new plates combine extra-thin and uniform wall thickness with a rigid upper PP deck for easy handli…

All BRAND PCR products are available in white plastic, uniformly colored with titanium dioxide (TiO2) for optimal results when performing quantitative PCR (gPCR) with fluorescent signals.   BRAND microcentrifuge tubes fit most common rotors and may be spun up to 20,000 RCF (10,000 RCF for 0.5mL). Manufactured from virgin polypropylene, these highly translucent tubes are free from flash, air bubbles, and streaks. Caps are…

The Matrix MG series comprises high performance instrumentation for Mid-Infrared gas and vapor phase spectroscopy as well as for gas quality control in process and environmental research.   Based on Bruker’s R&D 100 award winning MATRIX-F spectrometer with its well-known and patented RockSolid™ interferometer the MATRIX MG series provide compact size, outstanding stability and sensitivity. Features: Suited for t…

The EM27/SUN is an FTIR Remote Sensing analyzer dedicated for atmospheric measurements. Utilizing a CAMTracker system which is an innovative camera-based feedback system following the sun as light source. Its very compact and robust design as well as outstanding optical performance makes it ideal for long term measurement campaigns in remote areas with little infrastructure. Features: outstanding tracking accuracy…

BRANDplates® inertGrade™ 96-well plates are especially suited for cell culture applications when adhesion is not desired. These plates are specifically designed for the cultivation of suspension, tumor, and stem cells, as well as other spheroid or 3-dimensional tissue culture models. They feature a surface that reduces cell adhesion and protein absorption to minimize enzyme and cellular activation. All BRANDplates® inertGra…

BRAND UV-Cuvettes are a popular disposable alternative to quartz spectrophotometry cuvettes. They are excellent for DNA, RNA, and protein analyses as well as many other applications between 230-900nm. BRAND UV-Cuvettes are a more convenient and economical choice than quartz cuvettes. They eliminate the risk of cross-contamination from reuse and the need for cuvette washing. The proprietary material offers chemical compatibi…

Innovative cell culture plates and inserts for co-culture, migration/invasion assays, 3D tissue preparation and more.   The BRANDplates Insert System, co-developed with the Fraunhofer Society, offers an innovative expansion of the BRAND cell culture product line. The new Insert system consists of 24-well standard and 6-well specialized plates and strips of hanging cell culture inserts for applications such as co-culture,…

Adaptable Microplate Solution for Custom ELISA Applications. BRANDplates® Strip Plates are especially suited for laboratories designing custom ELISA applications, or desiring increased flexibility in their ELISA application. To ensure the effective binding of a wide range of antigens or antibodies to the microplate surface, the strip plates are available in two treatment types: pureGrade™ or immunoGrade™. The pureGrade™ plate…

The BRAND Liquid Handling Station pipetting robot handles routine tasks at high speed and with the highest precision. The LHS closes the gap between electronic pipettes and highly complex, expensive pipetting robots. It is a quiet and compact instrument with a unique front door allowing it be set up in tight quarters. The instrument has 7 working positions and 5 available liquid ends with single channel volumes up to 1000uL an…

The famous VERTEX80v is the gold standard of R&D FTIR spectroscopy regarding performance, sensitivity and flexibility. With the unique verTera THz extension the VERTEX 80v is now the first and only all-in-one system combining the advantages of FTIR and continuous wave THz spectroscopy, gaining access to an extremely broad spectral range and exciting new possibilities. Unique features: •Hybrid spectrometer FTIR/cw THz sp…

SiBrickScan (SBS) is a dedicated at-line system for the FTIR quantification of interstitial Oxygen in complete Silicon ingots, resulting in a precise concentration profile along the longitudinal axis. Accessing this information without sawing wafers or preparation of test samples is a major and cost saving advantage: qualify individual ingots before sawing and optimize the Si crystallization process! Unique SBS features: •…

In addition to the unmatched VERTEX 80v FTIR performance and flexibility, the verTera extension provides access to the single digit wavenumber regime and highest resolution without the need of cryogenically cooled components. This would be impossible for a conventional FTIR setup since bolometers at liquid Helium temperatures would be required. verTera offers a lot of exciting possibilities: Integrated state of the art c…

The BRAND Liquid Handling Station (LHS) pipetting robot handles routine tasks at high speed and with the highest precision.

Robust acid hydrolysis prior to fat extraction