Drug discovery > Lead Discovery Products & Reviews

The new Anion column line from Hamilton is designed to meet the special requirements of anion analysis.

Hamilton Robotics and Coastal Genomics have partnered to combine the NIMBUS platform with Ranger® Technology.

Hamilton RCX-10 And RCX-30 Columns for the Anion Exchange Separation of Carbohydrates

Separate Mono and Disaccharides or Carbohydrate Oligomers from DP1 to DP8.

Integration with STAR provides automated media exchange, GEM or cell extraction, reformatting new cell colonies in fresh tubes, harvesting cells for cell-based assay experiments run on the STAR or other equipment.

In-depth understanding of complete genome in human, aninal, plant and microbe with end-to-end services.  

Sequencing only service for customer-premade libraries at different read lengths and capacities to suit any cost, project scale and turnaround with the world-leading, powerful, and sophisticated sequencing platforms (Illumina, Pacbio, and Oxford Nanopore). 

16S/18S/ITS rRNA amplicon metagenomic sequencing employs universal primers to target specific regions to identify the phylogeny and taxonomy from complex microbiomes.

Single cell RNA sequencing uncovers the complexity of cellular diversity to employ the study of unusual cell types, cell-lineage associations, and samples of heterogeneous nature with 10x Genomics technology.

Long Read Sequencing (LRS) service employs cutting-edge technologies such as Oxford Nanopore and PacBio platforms for decoding complex genomes, completing transcriptomes, exploring metagenomes, and investigating structural variations with unmatched precision.  

Whole exome sequencing allows for sequencing human and mouse exomes in an array of panel options, which facilitates research contexts and clinical contexts.

Accelerate precision oncology with Crown Bioscience’s high-quality human biospecimens—comprehensive, clinically annotated samples including tumor tissue, plasma, and PBMCs, optimized for multi-omics research and biomarker discovery.

Cell Line-Derived Xenograft Models, Established multiple in vivo assay systems to evaluate novel anticancer compounds, with each assay specifically designed to understand a drug's mechanism of action, or an individual agent property.

CrownSyn™: Quantify and visualize drug synergy, antagonism, or additivity in vitro and in vivo with Crown Bioscience’s robust bioinformatics platform—empowering oncology researchers to optimize combination therapies with confidence.

Delve into biomarker discovery and drug development with Crown Bioscience’s next-generation proteomics services—leveraging 4D-DIA technology for deep, reproducible protein profiling and post-translational modification analysis.

Unlock immune insights with Crown Bioscience’s high-throughput flow cytometry—precisely characterize immune cell populations across tissues to elucidate drug mechanisms, assess pharmacodynamics, and optimize immunotherapies.

Accelerate the development of your immuno-oncology drugs with Crown Bioscience’s large panel of immunocompetent syngeneic models.

Crown Bioscience’s preclinical biomarker services help identify, validate, and analyze biomarkers across diverse in vitro and in vivo cancer models. Using multi-omics platforms and expert bioinformatics, these services support drug mechanism studies, patient stratification, and companion diagnostic development to guide oncology drug discovery.

PDX Models Empower your research with models that reflect today’s patients and treatments.

Unlock deeper insights into tissue organization and cellular interactions with Crown Bioscience’s spatial biology and digital pathology services, featuring advanced imaging, automated analysis, and high-throughput biomarker screening for applications in cancer research, immunology, and more.

OrganoidXplore™, Organoid Panel Screening Service

Explore your translational research with Crown Bioscience’s comprehensive genomics services—offering PCR/qPCR, next-generation sequencing, and advanced bioinformatics to deliver high-quality, reproducible data for biomarker discovery and drug development.

A compact benchtop design that incorporates 2 or 10 individually powered, high-output stirring stations which can prepare samples for content uniformity testing up to 90% faster than conventional methods.​

Rainbow is an in-situ, fiber optic probe-based, concentration monitor that measures concentration and changes in concentration in real-time without the need for sampling.