Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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InviTrap® Spin Universal RNA Mini Kit

Alkali Scientific

The InviTrap® Spin Universal RNA Mini Kit simplifies total RNA isolation from different starting materials such as cells, tissue, and blood. In addition, RUO protocols are available for e.g., RNA Cleanup from TRIzol®, simultaneous extraction of DNA and RNA or RNA extraction from other body fluids. Genomic DNA is removed without an enzymatic digestion step, and RNases are inactivated to prevent RNA degradation.

5.0/5.0
|1 Review




NZYGelpure

NZYTech

NZYGelpure kit is designed for the purification of DNA from TAE/TBE agarose gels and for direct purification of PCR products. Average recoveries range from 60 to 90% depending on the fragment size.

4.7/5.0
|1 Review

EUROBlotOne

Euroimmun

The EUROBlotOne is a compact tabletop device for fully automated processing of Euroimmun immunoblots for autoimmune, infection and allergy diagnostics. The device performs the identification and dilution of samples, as well as all incubation and washing steps. The incubated strips are dried and photographed and then evaluated using EUROLineScan software. This can be connected bidirectionally to the LIS or EUROLabOffice 4.0.

5.0/5.0
|1 Review


Prospect T1 High-frequency Ultrasound

Scintica

The Prospect T1 is an innovative high-frequency ultrasound system designed specifically for in vivo preclinical imaging in small animals such as mice and rats. This compact and cost-effective tablet-based system provides high-resolution images (up to 30 µm) and advanced capabilities to monitor changes in hemodynamics and observe anatomical structures in real-time.

4.7/5.0
|7 Reviews

iNSiGHT DXA

Scintica

The iNSiGHT DXA system is an in vivo Dual Energy X-Ray Absorptiometry (DXA/DEXA) technology for preclinical research. This fully shielded X-ray cabinet is suitable for small animal DXA applications – mice, rats, and animals of similar size (up to 5kg). Efficient body composition measurements allow for fast scan times of 25 seconds. Combined with its low-dose radiation, it’s ideal for longitudinal studies.

4.5/5.0
|2 Reviews

Lipid Droplet Staining

Dojindo EU GmbH

High selectivity to lipid droplet (low background) 4 colors available (blue, green, red, and deep red) High intracellular retentivity Applicable to both live and fixed cells

4.7/5.0
|1 Review




eQCM 15M

Gamry Instruments

A versatile electrochemical quartz crystal microbalance (EQCM) that accommodates any crystal from 1-15 MHz in any cell or holder.

5.0/5.0
|1 Review



In Vitro Vascular Permeability Assay (96-well)

Merck

This In Vitro Vascular Permeability Assay kit employs a 96-well plate, and provides an efficient system for evaluating the effects of chemicals & drug compounds on endothelial cell adsorption, transport & permeability. 96-Well Permeability Insert Assembly, Collagen-coated: One 96-well receiver tray containing 96 connected porous cell culture inserts pre-coated with type I rat-tail collagen. Receiver Tray, 96-Well: Two…

5.0/5.0
|1 Review


Cloning Platform – Single Cell Cloning and Imaging

iotaSciences

The Cloning Platform is a complete workflow solution for single-cell cloning. It offers automated handling of miniturised culture volumes as low as 200 nL and easy confirmation of monoclonality on day 0. Gentle handling with built-in programs for plating cells, feeding colonies, and harvesting clones maximises cloning efficiencies. With imaging and fluorescence options available, there's a configuration to suit your needs. 

4.8/5.0
|2 Reviews


Corning® 96-well Clear Flat Bottom UV-Transparent Microplate, 25 per Bag, without Lid, Nonsterile

Corning Life Sciences

96 well UV microplate has a UV-transparent well bottom and is ideal for determining protein and/or nucleic acid concentrations Certified for low background and consistent performance at 260 and 280nm Certified DNase- and RNase-free UV-transparent bottom is molded directly to an acrylic base for greater strength and maximum leak resistance Total well volume: 360 µL; recommended working volumes of 75 to 200 µL Lids are av…

5.0/5.0
|1 Review


DNA Ladders and Markers

Thermo Fisher Scientific

Thermo Scientific has a comprehensive range of DNA molecular weight markers which can be sub-divided into three groups: 1. Superladders derived from cloned and purified DNA fragment repeats, for quantitation and accurate sizing 2. High molecular weight markers from lambda DNA restriction digests 3. Lower molecular weight markers from plasmid and ØX174 restriction digests Most of these markers are now also available in a conven…

5.0/5.0
|3 Reviews


Corning® 96-well Flat Clear Bottom White Polystyrene TC-treated Microplates, Individually Wrapped, with Lid, Sterile

Corning Life Sciences

White walled plates enhance luminescent signals and have low background luminescence and fluorescence Bottoms are 60% thinner than conventional polystyrene plates, resulting in lower background fluorescence and enabling readings down to 340nm Opaque walls to prevent well-to-well crosstalk Optically clear flat well bottom permits direct microscopic viewing Can be used for both top and bottom reading instruments Flat bott…

4.7/5.0
|1 Review