Merck Products & Reviews

Accomplish highly effective transfection of CRISPR/Cas9 DNA, RNA, Cas9-gRNA RNP (ribonucleoprotein) complexes and siRNA to knock-out, modify or knock-down genes of interest in a wide variety of cell types.

Recombinant Cas9-D10A Nickase protein from Streptococcus pyogenes (~160 KD) is a ready-to-use reagent for genome engineering experiments.

The Sigma lenti CRISPR Non-Targeting Control is a lentiviral plasmid vector, which includes a gRNA sequence that does not target known human, mouse and rat genes. This vector is useful as a negative control in experiments using Sigma CRISPR lentiviral clones.

Human CRISPRi Kinase Phosphatase Drug Targets Kit contains 2 sub-pools of top 5 gRNAs per gene as well as a separate sub-pool of 5 supplemental gRNAs per gene for increased sensitivity and includes non-targeting controls built in.

The Lenti CRISPR Non-Target Control#1 (LV04 vector) is a lentiviral plasmid vector, which includes a gRNA sequence that does not target known human, mouse and rat genes. The DNA format of this control construct permits direct transfection in knockout experiments or use in the viral packaging process (for lentiviral-based knockdown experiments).

The Sigma lenti CRISPR Non-Targeting Control is a lentiviral system, which includes a gRNA sequence that does not target known human, mouse and rat genes. The non-targeting control lentivirus is useful as a negative control in experiments using Sigma CRISPR lentiviral clones.

Pooled CRISPR screening with 10x genomics compatibility for discovery at single cell resolution

Animal-free passive blocking antibody

Animal-free active blocking antibody

Purospher™ STAR HPLC and UHPLC columns are based on 99.9999 % ultra-pure fully porous silica. Designed for the separation of basic, neutral, and metal chelating compounds, they assure excellent peak symmetry even with simple aqueous mobile phases, offering outstanding pH and thermal stability

Discovery® HPLC Columns are robust, rugged and short-length, designed for rapid LC-MS analysis. They have C18, C8, Cyano and HS F5 phase-chemistries.

Astec ® CYCLOBOND™ Chiral HPLC Columns include CYCLOBOND™ I 2000 and CYCLOBOND™ II series of columns for effective separation of chiral molecules.

Astec ® CHIROBIOTIC ® Chiral HPLC Columns assure effective chiral separations and highly selective achiral separations, with their macrocyclic glycoprotein based stationary phases

Discover product solutions for complete PFAS analysis workflow, starting with sample collection and preparation, and standardization and chromatographic analysis 

Discover our efficient product solutions for effective cannabis quality testing. From sample homogenization and preparation, to standardization and characterization, we have got advanced products covering the cannabis testing workflow.

Certified reference material, Trace CERT ® , 100 μg/mL each component in methanol, ampule of 1 mL.

Platform can perform automatic analysis of sample's purity, identification and degradation of compounds through calibrated algorithm-based digital references.

Hi-Flow™ Plus Membrane 75 Slit Rolls

Hi-Flow™ Plus Membrane 180 Slit Rolls

Hi-Flow™ Plus Membrane 120 Slit Rolls

Hi-Flow™ Plus Membrane 135 Slit Rolls

Hi-Flow™ Plus Membrane 90 Slit Rolls  

For researchers who want to do cell cycle research at their benchtop, Guava Cell Cycle assay can be used for measuring G0/G1, S, and G2/M phase distributions. Based on the established method of whole-cell staining with propidium iodide (PI), Guava's cell cycle assay is easy to learn. Guava Cell Cycle software includes markers that can be set for quick assessment of G0/G1, S, and G2/M phase cell cycle percentages as data is bei…

Apoptosis, or programmed cell death, is a highly regulated pathway that is important in normal developmental processes as well as many diseases. Cells undergoing apoptosis are identifiable by a number of characteristics, including changes in mitochonrial membrane potential, transport of phosphatidylserine (PS) to the membrane surface, activation of caspase proteases, and DNA fragmentation in the nucleus. Guava offers four apop…

Guava Technologies' ViaCount assay is revolutionizing the way cell counting and viability assessment are done in today's laboratories. Fast, automated, and highly reproducible, the Guava ViaCount assay addresses many of the difficulties of conventional cell counting and viability assessment methods. The Guava ViaCount assay provides: Cell counts up to ten times faster than manual counting, in a convenient turnkey assay.…