Member since: 2020
Our "Gold Standard" as secondary assay system for electrogenic transporters.
Application Area: Drug discovery, secondary transporter assays
"The SUERFE2R is our "Gold Standard" as a secondary assay system for electrogenic transporters. Some experience is needed, as usual, for these kind of assay systems, but the instrument is easy to use and data evaluation is easy to conduct. The assay and technical support is superb."
The SURFE²R 96SE is designed for activity measurement of electrogenic membrane transporters and pumps, which generate currents too low to resolve by patch clamp or which are not expressed in membranes accessible for patch clamp (e.g. bacterial, organelles). The technology enables label- and radioactivity-free real time measurements with high time resolution.
The SURFE²R 96SE uses sensors in a standard 96-well plate format. Membranes containing the protein of interest are adsorbed onto these sensors. Any substrate can be added to activate the transporter. The resulting transport or binding currents will be detected and analyzed accordingly. The whole process, from sample preparation and measurement to data analysis, is fully automated.