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Simoa® Service by RayBiotech Inc.

Manufacturer RayBiotech Inc.  |  Available Worldwide
Single molecule array (Simoa) testing is a protein detection technique that is orders of magnitude more sensitive than standard sandwich based immunoassay techniques. Traditional ELISA measurements are limited to pg/ml levels of detection. The RayBio Ultrasensitive Simoa Testing Services can achieve sensitivity as low as femtogram (fg/ml) levels, allowing the quantification of biomarkers at concentrations previously difficult or impossible to measure.

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Simoa® Service
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How It Works

Simoa is based upon the isolation of individual immunocomplexes on paramagnetic beads using standard ELISA reagents. The main difference between Simoa and conventional immunoassays lies in the ability to trap single molecules in femtoliter-sized wells, allowing for a "digital" readout of each individual bead to determine if it is bound to the target analyte or not.


Over 80 pre-validated analytes are available, including cytokines, growth factors, neurodegenerative markers, and more. Multiplexing is also available for up to 4 analytes.