How It Works
Simoa is based upon the isolation of individual immunocomplexes on paramagnetic beads using standard ELISA reagents. The main difference between Simoa and conventional immunoassays lies in the ability to trap single molecules in femtoliter-sized wells, allowing for a "digital" readout of each individual bead to determine if it is bound to the target analyte or not.
Over 80 pre-validated analytes are available, including cytokines, growth factors, neurodegenerative markers, and more. Multiplexing is also available for up to 4 analytes.