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Orbitrap Exploris MX

Thermo Fisher ScientificAvailable: Worldwide

Accelerate biopharmaceutical late-stage development, commercialization, manufacturing, and quality control (QC) by easily and reliably obtaining compliance-ready, high-quality mass information.

Thermo Fisher Scientific

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Description

The Thermo Scientific Orbitrap Exploris MX mass detector is a great fit for deploying routine mass monitoring.

In addition to high-resolution mass detection provided by Thermo Scientific Orbitrap mass analyzers, this fit-for-purpose system is simple to operate and compliance-ready with Thermo Scientific Chromeleon chromatography data system (CDS) software. Consistent performance between the Thermo Scientific Orbitrap Exploris 240 mass spectrometer and Orbitrap Exploris MX detector ensures seamless method transfer from development to QC.

Streamlining characterization and monitoring of oligonucleotide impurities using an Orbitrap-based LC-HRAM-MS platform

Ion-pairing reversed-phase liquid chromatography (IPRP-LC) has been established as the main chromatographic technique for the analysis of oligonucleotide therapeutics, especially when connected to mass spectrometry. However, chromatographic approaches alone still suffer from an inherent lack of selectivity.

Explore how a streamlined approach using Orbitrap-based LC-HRAM-MS platforms can be a valuable tool for the characterization and monitoring of therapeutic oligonucleotide impurities.

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