Products & ReviewGeneral Lab

Optima XPN Ultracentrifuge

Beckman Coulter Life SciencesA94469Available: Worldwide

Speed and performance for your high performance processing applications

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Description

If you’re looking for practicality, but desire the functionality and performance of an ultracentrifuge, you’ve found the perfect instrument: the Optima XE and Optima XPN. This ultracentrifuge provides all of the features you’d expect, along with some very beneficial enhancements you won’t find anywhere else. With total-system design in mind from the start, we created the Optima XE to simplify use, increase productivity, and reduce error. You’ll applaud its intelligent user interface, multi-layered BioSafety features, and energy efficiency. And of course, our total system design backed by our exclusive rotors, labware, and unparalleled service. Possessing all of the attributes of our entry-level model, the XE, the Optima XPN boasts additional enhancements that will simplify use, optimize control and security, and increase productivity. You’ll applaud its intelligent user interface, networking and remote control capabilities, and energy efficiency. And of course, our total system design backed by our exclusive rotors, labware, and unparalleled service.

Features:

  • Large touch-screen display - Displays more data
  • Easy to read and navigate
  • Viewable from across the lab
  • Energy efficient - Regenerative braking returns energy to local circuit reducing utility costs
  • Highly efficient thermoelectric cooling results in lower power consumption
  • Total system design - The Optima XE, its rotors and its labware are designed, manufactured, and tested as an integrated system to ensure optimal performance and safety for your lab
  • Zonal and continuous flow operation screens - Intuitive, graphical step-by-step interface simplifies workflow
  • Multilingual software - Includes nine languages for error-free operation
  • Improved power tolerance - Maintains runs during power fluctuations
  • Handles a wider tolerated range of 180 VAC to 264 VAC
  • Tracks power interruption data to convey if parameters remained within an acceptable range
  • Quiet-drive technology - Designed for lowest drive noise – this is the quietest floor model on the market
  • Operates at less than 51 dBA. Context-sensitive on-screen help - Find answers easily
  • Reduce training time and user error.

Brochures

Application NoteGeneral Lab

Principles of Continuous Flow Centrifugation

This application note provides a comprehensive guide to continuous flow centrifugation, describing what equipment might be needed to perform this technique as well as tips and FAQs. Continuous flow centrifugation is a method that can be employed to drastically decrease operational times for sample processing particularly if the sample size is large, sedimentation rate is low or the acceleration/deceleration rate is slow.


Application NoteLife Sciences

Analysis of Nanotoxicity: Particle Characterization & Centrifugation

This application note provides insight into the inherent shortcomings that are present in traditional cellular toxicity assays, and how these shortcomings are magnified when the toxicity assay involves nanomaterial. Nanomedicine is a field common to materials scientists, chemists, biomedical engineers, biologists and medical scientists. Beckman Coulter tools enable quantification of cellular toxicity caused by nanoparticles; reducing time to remove aggregated particles and quantifying cell toxicity in the presence of single-walled carbon nanotubes.


Application NoteLife Sciences

Stability of the Human Immunodeficiency Virus-1 Reverse Transcriptase Heterodimer

This application note describes the characterization of a heteroassociating system. The thermodissociation is studied using band sedimentation analysis, whilst the electrostatic dissociation is studied using boundary sedimentation analysis. Analytical ultracentrifugation represents a powerful methodology for expressing HIV-1 viral components. In conjunction with appropriate data analysis methodologies, analytical ultracentrifugation can be used to examine sample purity, detect and characterize conformational changes, determine subunit stoichiometries, characterize assembly and disassembly mechanisms of macromolecular complexes, and measure equilibrium constants and thermodynamic parameters of associating systems.



Application NoteLife Sciences

Exosome-Depleted FBS Using Beckman Coulter Centrifugation

This application note discusses methods of exosome isolation from cell cultures with a centrifugation protocol example. Also, it explains the process for “home-brewing” exosome-depleted FBS by ultracentrifugation and compare the cell viability and media depletion percentage from two separate cell lines after treatment with different media types.

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