Eppendorf New Brunswick™ BioFlo®/CelliGen® 510
BioFlo 510 Fermentors and CelliGen 510 Bioreactors are intermediate systems ideal for pilot to small scale production processes. The modular design features a wide variety of standard options allowing this system to be flexible enough to meet most process requirements. Eppendorf New Brunswick™ BioFlo®/CelliGen® 510 Working volumes: 10.75 L to 32.0 L Applications: Laboratory and pilot scale fermentat…
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Great instrument
production of therapeutic protein
Very good controls as compared to other competitors. very user friendly and knowledgeable support staff in India.
Review Date: 15 Dec 2015 | Eppendorf
BioFlo 510 Fermentors and CelliGen 510 Bioreactors are intermediate systems ideal for pilot to small scale production processes.
The modular design features a wide variety of standard options allowing this system to be flexible enough to meet most process requirements.
Eppendorf New Brunswick™ BioFlo®/CelliGen® 510 Working volumes:
- 10.75 L to 32.0 L
Applications:
- Laboratory and pilot scale fermentation of aerobic and anaerobic bacteria, yeasts, and fungi;
- Laboratory and pilot scale cell culture of mammalian, insect, and human cell lines;
- Special applications such as stem cell culture, vaccine, monoclonal antibody, or biofuel/biopolymer production;
- Suitable for batch, fed batch, and continuous processes
Easy perfusion for anchorage-dependent cell culture
Anchorage-dependent cells, such as Vero cells, are widely used as a platform for viral vaccine production. In perfusion bioprocesses it is possible to constantly add nutrients and to remove byproducts, while retaining the cells in the bioreactor. In this application note, Eppendorf demonstrates how the BioFlo 320 vessel equipped with a spin filter for microcarrier can be used as a platform for high-density Vero cell culture, suitable for vaccine production.
Standardizing microbiome research – Culture from discovery to production
In this poster, Eppendorf outlines a microbiome culture workflow covering the diverse culturing needs of gut microbes (including oxygen, pH, and temperature control) and the scalable bioprocess systems that are available for culture research to production.
Vero Cell-based Vaccine Production: Rabies and Influenza Cell lines, Media and Bioreactor Options
The Vero cell line is one of the most satisfactory based on its stability and well-documented performance in quality and quantity of viral yield. It has received FDA approval and is used throughout the world. This white paper reviews strategies for optimizing vaccine production with examples given for rabies and influenza using cell culture systems.
Which Impeller Is Right for Your Cell Line? A Guide to Impeller Selection for Stirred-Tank Bioreactors
This application note describes six commonly used fermentor and bioreactor impellers, explain how they work, and identify which may perform best for culturing certain animal, insect, plant, yeast, and bacterial cell lines.
Standardizing microbiome research: culture from discovery to production
Download the microbiome workflow poster from Eppendorf
Avacta and Selexis Partner to Develop Cell Line for Clinical Manufacturing
Avacta’s first Affimer clinical candidate is a potent PD-L1 antagonist under development for solid tumor indications as the basis of bispecific and combination therapies
