Status:
ReviewerMember since: 2021
Organization: University of Michigan
Excellent product, works extremely well!
Application Area:DNA clean-up
"Excellent product, works easily and quickly, had no issues needing after-sales care, shipped quickly, wonderful product!"
Status:
ReviewerMember since: 2022
Organization: UCI
Great results, no carryover.
Application Area:PCR cleanup
"The kit was very easy to use especially because of the spin column that was provided that fits the collection tube. The quality of the DNA is higher and the contamination carryover is pretty much nonexistent. Well designed."
Status:
ReviewerMember since: 2022
Organization: UW - Madison
Fast, reliable, and efficient.
Application Area:Vaccine Development
"This kit was easy to use and it take under 5 minutes to complete the process. The most important thing is, I could recover more DNA than other products I used before."
Status:
ReviewerMember since: 2022
Organization: Stanford University School of Medicine - Neurology Dept.
Easy to use and packaged very well.
Application Area:Help with experiment
"The ordering and shipping process was great. I appreciate how easy it was to order and will use this vendor again as out students here at Stanford University do experiments that need reliable equipment for testing."
Status:
ReviewerMember since: 2020
Organization: University of Connecticut
Great recovery for single cell marine ciliates
Application Area:DNA extraction and purification for single cell PCR
"This is our lab’s go-to for extraction and purification of single cell eukaryotes (marine ciliates) for downstream PCR amplification. It’s able to remove inhibitors in seawater while also allowing for the recovery of ample DNA for PCR from a single cell."
Status:
ReviewerMember since: 2022
Organization: Harvard Medical School
The cleanest (and high-quality) DNA samples I have ever obtained.
Application Area:Cleaning samples before high-throughput sequencing
"We routinely prepare DNA samples for high-throughput sequencing. So, we really understand how precious this material is. After comparing different methods for cleaning DNA (old-school phenol/chloroform and cleaning columns from other companies), we realized that using this product gives us the best results. Now, this step is a must-do in our pipeline."
Status:
ReviewerMember since: 2020
Organization: RealSeq Biosciences
Amazing, consisent, reproducible results
Application Area:RNA sequencing
"The Zymo DNA Clean and concentrator is a critical kit in the workflow at our RNA sequencing service company. The ease with which this experiment is carried out and the straightforward manner in which one can readily concentrate and purify DNA is extraordinarily fast. We wouldn't be able to get done as much as we get done if it weren't for this kit!"
Status:
ReviewerMember since: 2022
Organization: Humboldt State University
Very helpful, and all parts of the process included.
Application Area:PCR cleaning
"The product thus far has worked well with my tissue."
Status:
ReviewerMember since: 2019
Organization: Hope College Biology
Great product-actually works!
Application Area:Clean up genomic DNA prior to PCR
"For troublesome PCR reactions of genomic samples, I use the DNA clean & concentrator kit. PCR works likes a charm after clean-up!"
Status:
Advanced ReviewerMember since: 2021
Organization: the Univeriaty of Alabama in Huntsville
Easy to use, definitely good to have in the lab.
Application Area:RNA seq
"This has been very convenient clean-up / concentrator I always use with RNA isolation kit. Especially when handling small quantities of input samples, it is so crucial to be able to concentrate for the downstream application (e.g. 1st strand cDNA prep)"
Status:
ReviewerMember since: 2021
Organization: Baylor College of Medicine
Quick and easy way to concentrate DNA
Application Area:Used to concentrate DNA for various NGS applications that require highly concentrated inputs.
"This product is very straightforward and user friendly. There are only a couple of steps and from start-to-finish, you can do it in about 10 minutes if you have everything setup ready to go. We particularly like using it when heat/vacuum methods to concentrate DNA are not available."
Status:
ReviewerMember since: 2021
Organization: OU Health Science Center
Efficient and reliable product
Application Area:PCR cDNA clean up for cloning gene
"Zymo's Clean & Concentrator-5 kit allows me to efficiently and easily clean my PCR product after amplification in as little as 15 minutes (depending on the number of samples being processed). There is almost no sample lost in the column during elution. This is definitely a very reliable product to use on crucial samples."
Status:
ReviewerMember since: 2021
Organization: Auburn University
Great for WGS prep!
Application Area:DNA preparation for Whole Genome Sequencing
"The Zymo Clean & Concentrator kit has been a huge help for preparing samples for WGS. In a few simple steps I can concentrate very dilute samples into a small aliquot that is ready to ship for sequencing. The kit also removes EDTA from my samples that would otherwise have interfered with the WGS process. The cost is a small price to pay for better quality in my sequence data!"
Status:
ReviewerMember since: 2021
Organization: UConn
Worked for standard DNA, but not for mysterious DNA.
Application Area:Purify DNA post targeted gene capture & PCR
"Attempted to use this product in order to troubleshoot why our libraries were stuck in the supernatant after a bead clean up. With our standard DNA, the columns worked great, but our problematic DNA staying stuck in the supernatant even with the Zymo clenaing column. Certainly a mystery."
Status:
ReviewerMember since: 2021
Organization: Penn Vet
Good one, will buy more.
Application Area:ChIP-seq
"Generally, this one is good. When you don't want to do beads purification, column purification is easier. This one is very reliable, and easy to use. Especially the column design, you don't need to worry about residual alcohol on the O-ring."
Status:
ReviewerMember since: 2021
Organization: University of Colorado Denver|Anschutz Medical Campus
Good results.
Application Area:PCR purification
"Purified DNA in just minutes. Easy to work with."
Status:
ReviewerMember since: 2021
Organization: San Diego Biomedical Research Institute
I prefer this most.
Application Area:Measuring replication timing in different cell lines
"DNA Clean & Concentrator™-5 kit is really good in terms of yield. It is easy to use. Handling of material is very easy. I found it to be the best kit so far."
Status:
ReviewerMember since: 2021
Organization: Houston Methodist Research Institute
Overall, very good product.
Application Area:Isolate DNA
"Very easy to use (10-15min for 3 samples) and yields high quality DNA. Great for digestion clean ups and for further clean ups after gel recovery."
Status:
Advanced ReviewerMember since: 2015
Organization: Dpt. DSV- University of Trieste
It is very easy to use even for the less trained people and the results are very good.
Application Area:Cloning
"The use of this kit definitely simplified the cloning protocol in our lab, allowing the preparation of the plasmid vector in three-steps. Skipping the electophoresis on agarose gel lets us save time and to achieve a vector concentration that is far higher than that obtained with the purification from the gel band."
Status:
ReviewerMember since: 2021
Organization: National Cancer Center/Cancer Hospital
Very useful! Even better than I expected!
Application Area:Medical experiments
"Quick, 2 minute recovery of ultra-pure DNA from PCR, enzymatic reactions, and other sources. "
Status:
ReviewerMember since: 2021
Organization: University of Maryland Baltimore County
Will use in our lab for a very long time.
Application Area:DNA cloning
"The product is very effective and the instructions are easy to follow."
Status:
ReviewerMember since: 2021
Organization: CICAMS
Magnificent results, can’t live without this product!
Application Area:DNA purification
"Quick to get high-purity DNA. Compatible with subsequent sequencing, PCR experiments, etc. Highly suggested!"
Status:
ReviewerMember since: 2021
Organization: University of Maryland Baltimore County
Results are great, our lab will be using forerver.
Application Area:Clean up PCR samples, to use for cloning.
"The product is very effective, it gives us a good concentration of DNA. The instructions are easy to follow, the supplies are organized and labeled properly."
Status:
ReviewerMember since: 2021
Organization: ISU College of Pharmacy
Convenient kit, quick outcomes.
Application Area:Genomic profiling
"The DNA Clean and Concentrator kit conveniently brings all reagents together in one kit with easy to follow instructions that work together, and as a result yield consistent results with little chance for error."
Status:
ReviewerMember since: 2021
Organization: Harvard university
Great reliable product!
Application Area:Molecular cloning
"Zymo PCR purification kit is reliable and always gives me high quality DNA purifications. Our lab have been using them for years and have never had a problem."
Status:
ReviewerMember since: 2021
Organization: Curtin University
Quick, easy and just works
Application Area:DNA purification
"Super simple column purification kit that lets you elute DNA in as little as 6 microlitres. We use it to concentrate and clean DNA after gel extractions for downstream cloning or sequencing purposes. "
Status:
ReviewerMember since: 2021
Organization: FAU HBOI
Great product. Saved more than one project!
Application Area:DNA isolation/cleaning
"Easy and quick to use. Zymo support is great for troubleshooting and optimization. Makes dirty DNA extraction from non-model organisms usable for high sensitivity down stream applications. "
Status:
ReviewerMember since: 2021
Organization: Harvard university
Great realiable product.
Application Area:Molecular cloning
"Zymo clean and concentrate has always been reliable and gives high quality DNA. Our lab has used this product for years and has never had any issues."
Status:
ReviewerMember since: 2021
Organization: University of Pittsburgh
Use them all the time.
Application Area:Molecular biology
"Elute in smallest volume possible - excellent for downstream applications!"
Status:
ReviewerMember since: 2019
Organization: SUNY Plattsburgh
Consistent successful results!
Application Area:Phage research
"This product is of great value, and is simple to use in the classroom. Students are able to access the protocols online and the approach is straightforward."
Status:
ReviewerMember since: 2021
Organization: University of Utah
Easy to use and good results.
Application Area:Molecular and cell biology
"This kit is a great alternative to ethanol precipitation for DNA concentration and cleaning up PCR products so they can be quantified. The instructions make modifying the procedure for different types of DNA easy."
Status:
ReviewerMember since: 2021
Organization: UIUC
Great reults!
Application Area:DNA purification
"Its efficiency is much better than the other products with the same function. I wanted to purify products for nick translation experiments that have labeled dUTP on the strands and the efficiency of other kits on these products are very low. I tried DNA Clean & Concentrator-5 which could purify my product perfectly."
Status:
Advanced ReviewerMember since: 2019
Organization: The George Washington University
Great product to purify PCR products without gel & concentrate with 6 ul elution.
Application Area:Purify PCR products without gel purification
"We use this to purify PCR products when not run on a gel. This is a great product and easy to use. Small volume elution (6 ul) is the best aspect of this product because you can concentrate DNA in dilute samples."
Status:
ReviewerMember since: 2021
Organization: Towson University
Great results and not time consuming! Product ends up cleaner and more concentrated.
Application Area:DNA cleaning for cell biology
"The product is very easy to use and takes less than 10 minutes for one sample. My products always end up with a higher concentration and show up cleaner on a UV-Vis Spec. I've been using it for a year now and I highly recommend this product!"
Status:
ReviewerMember since: 2020
Organization: Microbiome Insights
Good product, and reliable.
Application Area:DNA clean and concentrator
"Works as advertized, use it on NGS library and this help clean and concentrate the library after gel size selection."
Status:
ReviewerMember since: 2020
Organization: RealSeq Biosciences
Extremely easy and quick to use!
Application Area:Concentrate samples for better yields
"This kit, like most Zymo Research kits, is very straightforward and easy to use. The protocol takes about a few minutes to go through depending on how many samples you have. It does what it is supposed to do: give me higher yields from my PCR products if need be, which is useful for what we do here at RealSeq Biosciences."
Status:
ReviewerMember since: 2020
Organization: Northumbria University
Good option for increasing quality of gDNA samples.
Application Area:Concentrating DNA samples
"Effective at increasing concentration and purity of DNA samples post extraction."
Status:
ReviewerMember since: 2020
Organization: UTMB
Quality, and a reasonable price.
Application Area:Cloning
"Very easy to use and quick. Yields are pretty good even with the low recommended volume for elution."
Status:
ReviewerMember since: 2020
Organization: Cornell University
Love the Zymo cleanup kits!
Application Area:Clean up of PCR amplicons and plasmid digests
"Love the Zymo cleanup columns. I used them for DNA and RNA. There are no extra bits of residual wash buffer on the side like other columns, and the cleanup procedure is fast and easy."
Status:
ReviewerMember since: 2020
Organization: NC State University
Gets the DNA totally CLEAN!
Application Area:Library preparation
"This product works extremely well for purifying and concentrating DNA for Illumina libraries. My NanoDrop readings showed heavy protein contamination after CTAB DNA extraction from plant tissue and this kit cleared it right up in less than half an hour. The new A260/A280 ratio was exactly 1.8 after using the kit. I have not tried it for large fragment DNA, though. I would definitely recommend this kit if you have some contamination in samples for PCR or short read library prep."
Status:
ReviewerMember since: 2019
Organization: University of Iowa
Superior in terms of price, reliability & quality. The best in the business.
Application Area:Purifying DNA during bacterial cloning steps
"For a very long time, I was using QIAGEN, and to a lesser extend Invitrogen products for DNA purification. Recently, I switched over to Zymo Research DNA Clean & Concentrator - 5 kit. Not only did I find it cheaper, but also easier and less time consuming. It also gives very reliable & consistent results. The quality of the product is better than what I have been using until now. This product is also more suitable for my purpose in terms of how well I can adapt in terms of starting material and elution volume, as well as the relative ease and convenience when using the product. "
Status:
ReviewerMember since: 2019
Organization: University of Southern California
Good for some applications and sample types, but not others.
Application Area:Genotyping
"Tried using this kit to concentrate genomic DNA isolated from FFPE tissue for genotyping downstream. Kit was easy to use and quick, however, a lot of DNA seemed to be lost during recovery and my DNA was not concentrated, so in the end, it was not a good product for my needs."
Status:
ReviewerMember since: 2019
Organization: University Of California Riverside
Does a great job without too much fuss.
Application Area:PCR clean up
"Enzymatic clean-up is great if you have lots of samples, but when I only have a dozen or so, the "Clean & Concentrator" kit gets it done in around 15-20 minutes. Slightly more expensive than enzymatic clean up, but excellent value among the various column-based clean up kits on the market, and of at least comparable quality. The only things I would change: It needs much less of the binding buffer (1 bottle is more than enough) and needs a little more of the elution buffer (10-20% more would be really useful)."
Status:
ReviewerMember since: 2019
Organization: Yale University
Excellent product for small quantity DNA cleanup.
Application Area:HiChIP cleanup
"Tried every other kit on the market, only this one preserved enough DNA for complex library generation downstream."
Status:
ReviewerMember since: 2019
Organization: University of Utah
Fast, easy cleanup.
Application Area:Cleanup of gDNA from fecal DNA extractions
"My gDNA fecal extractions were low concentration and pretty contaminated, instead of doing them again I used this cleanup kit which was fast, easy, and worked like a charm. All my samples had a good concentration for sequencing after using this kit!"
Status:
ReviewerMember since: 2019
Organization: University of Florence, Dept of Health Science
Very good reaults.
Application Area:Molecular biology, genomics, gene expression analysis
"Easy to use, allows you to concentrate samples without affecting the quality of the sample (differently to methods that use warming)."
Status:
ReviewerMember since: 2019
Organization: CASPR Bio
Great results! I always prefer Zymo on my bench.
Application Area:Purification of PCR products
"It's a great product. Easy to use and very useful because we need to concentrate PCR products for our validation of sensitivity in-vitro and it really works well. In addition, the kit conserves the quality of the DNA. Excellent balance between price and quality. I would choose it every time!"
Status:
ReviewerMember since: 2019
Organization: University of Utah
Best yields of all cleanup kits we have tried.
Application Area:Clean up PCR and DNA samples for downstream applications
"A very simple protocol and reliable results. We get the best yields from this kit."
Status:
ReviewerMember since: 2019
Organization: CITY OF HOPE
Great value and very consistent results.
Application Area:Clean up of DNA (e.g. after ChIP or cloning)
"The DNA Clean & Concentrator-5 is a great product that removes the need to carry out lengthy precipitations for routine DNA clean up. It is easy to use and allows you to elute in very low volumes with high yield and good purity values. Would recommend to everyone."
Status:
ReviewerMember since: 2019
Organization: University of Louisville
Great product, great value, must have!
Application Area:Purification of PCR products directly from reactions; purification after restriction digests
"This is a very easy way to clean up DNA fragments from a variety of upstream applications (PCR, restriction digests, etc). We get good yield and clean products for downstream steps. We even used this once to purify a radiolabelled probe away from unincorporated nucleotides."
Status:
ReviewerMember since: 2019
Organization: City of Hope
Great value.
Application Area:Purify products for cloning
"Kit is easy to use. Process is quick and yields clean product for downstream applications."
Status:
ReviewerMember since: 2019
Organization: IQB, the University of Tokyo
Great product!
Application Area:Pretreatment of NGS DNA sample
"Zymopure series columns work very well. Elution volume can be kept at low amount. Our DNA prep methods require concentration steps for NGS library prep. Hopefully, this kit will be cheaper in Japan."
Status:
ReviewerMember since: 2016
Organization: ICR
Great product, just what we needed to process samples in unknown elution buffer!
Application Area:DNA buffer replacement
"Great product, easy to use and implement. DNA recovery rate is high. Perfect for concentrating your DNA sample for low volume input assays, as well as buffer replacement tool when processing samples eluted in unknown buffer, and your downstream assays require low EDTA or salt content."
Status:
ReviewerMember since: 2019
Organization: The University of akron
Budget PCR purification.
Application Area:Zebrafish cell culture
"Easy to use, gets the job done. Cheapest kit that I could find among competitors. Purifies PCR products >100bp flawlessly (and quickly; <5mins). I recommend this product"
Status:
ReviewerMember since: 2019
Organization: Molecular BioSciences
Very good kit!
Application Area:Gene expression profiling, library preparation for NGS
"Easy-to-use, provides reproducible results. Perfect for low amounts in combination with class CI columns."
Status:
ReviewerMember since: 2019
Organization: University Hospital Essen
Excellent clean-up system. I love it!
Application Area:Concentration of nucleic acids, clean-up of PCR fragments for T7-Assay
"This product is easy to use, straight-forward and requires only a minimum amount of time. It always works - which is not true for many other clean-up systems! Elution in quite small volumes is really cool."
Status:
ReviewerMember since: 2016
Organization: Loyola University Chicago
Great product but overpriced
Application Area:Clean up of amplicons for sequencing
"I didn't need to contact after sales service so please ignore my rating for the service. This is a convenient and simple product to use. It is very expensive considering the simplicity of the product."
Status:
ReviewerMember since: 2016
Organization: Institute for Molecular Medicine Finland FIMM
Easy to use, great worth for money!
Application Area:Clean up samples for NGS analysis
"The product is very easy to use and it is very affordable price."
Status:
ReviewerMember since: 2016
Organization: Georgia Tech
Good clean DNA for downstream uses but some loss of sample.
Application Area:DNA cleanup
"The kit was easy to use and produced good clean DNA samples that we could use for NGS sequencing. There is considerable loss of sample so the kit requires a decent starting concentration of DNA but we were able to clean-up samples that we could not clean with more traditional methods (phenol extraction/ethanol precipitation)."
Status:
ReviewerMember since: 2016
Organization: University of Alberta
Great price, high quality.
Application Area:DNA purification
"I bought it because of its great price. After use, I found it have the same quality with Qiagen similar product."
Status:
ReviewerMember since: 2016
Organization: IRCC Candiolo
Say goodbye to your contaminated DNA.
Application Area:Purification of DNA from contaminant
"I used this product to clean DNA extracted from FFPE tissue and highly contaminated with phenol according to the spectrophotometer profile (ultra low 260/230 ratio, and 260/280 close to 1). The kit allowed to removal of all the contaminant, getting perfect 260/230 and 260/280 without major loss of template according to quantification via Qubit. The protocol is easy, as usual with products from Zymo, and the different parts of the kit can be bought separately. The elution can be restricted to a very low volume, allowing concentration of the template. The only negative aspect, is the necessity to use an elution buffer with pH>7 such as tris which my NGS facility does not accept."
Status:
ReviewerMember since: 2016
Organization: UW
Great kit for NGS libraries prep.
Application Area:NGS library prep
"Recovery efficiency is high. Ease of use and better value at price comparing to QIAGEN MinElute PCR Purification Kit. Helpful, friendly, and immediate online tech support, should you have any questions."
Status:
ReviewerMember since: 2016
Organization: University of Florida
All post extraction steps in one product.
Application Area:Cleaning metagenomic DNA.
"All the Zymo products I've used, including the DNA Clean & Concentrator™-5, are phenomenal. I work with very dirty samples - marine microbialites - contaminated with salts, extra polymeric substances, sediments, proteins, and, after collection, the preservative RNAlater. Zymo DNA and RNA Clean and Concentrator is the only product like it that has successfully cleaned my samples of all the contaminants remaining after extraction, including the phenol that carries over from the extraction itself. Additionally, my samples are very low in nucleic acid yield, so the added benefit of having one product to clean and concentrate means that I lose less material in downstream steps. I can even do a DNase treatment in the RNA C&C-5 kit. I'm very happy with Zymo's products."
Status:
ReviewerMember since: 2016
Organization: Stanford University
Fairly effective. Seems like a good option for removal of plant PCR inhibitors.
Application Area:Isolation of DNA from root tips (fungal amplification).
"This kit was very easy to use, and had a straight forward protocol. Post cleaning DNA showed significant improvement in amplification."
Status:
ReviewerMember since: 2016
Organization: UC Riverside
Great value for a fair price.
Application Area:Purification of PCR product or digested plasmid for cloning.
"Product is easy to use and yields are good. The protocol is also fast."
Status:
ReviewerMember since: 2016
Organization: NWP
Great value, works just as well or better than similar more expensive kits.
Application Area:Preparing PCR products for sequencing
"I've been working in laboratories for many years and have had the chance to use many different PCR cleanup kits. I was able to get a free sample of the Zymo DNA clean & concentrate kits to prepare my PCR products for sanger sequencing. They worked great, and were much less expensive to use than my previous kit. The DNA clean & concentrate kits are very easy to use. One added feature that I really appreciated is that you can buy all of the kit components separate so if you have extra buffers you can just order more columns to stretch your dollar even more. I highly recommend this product."
Status:
ReviewerMember since: 2016
Organization: Massachusetts General Hospital
Easy to use and it does not require a lot of time.
Application Area:DNA purification.
"Really easy to use, instructions are super clear, and is a fast method to clean DNA for sequencing. The price is super affordable."
Status:
ReviewerMember since: 2016
Organization: EntoGenetics Inc.
A lab staple.
Application Area:PCR and digest cleanup
"These clean and concentrate cartridges do just that. They take and DNA prep, remove everything else and put it out in a few micro liters. They are well priced, easy to use, and the quick protocol is just the same with every sample. We keep them stocked in the lab to grab anytime there a a prep to be cleaned, enzyme removed, buffer changed, or just reduced in volume."
Status:
Advanced ReviewerMember since: 2016
Organization: Florida State University
Great quality and easy to use
Application Area:DNA purification during NGS sample prep
"This product allows elution of purified DNA into small volume in a great quality. The purification process is very fast. Each component of the kit can be purchased separately, which is very convenient and environment friendly."
Status:
ReviewerMember since: 2016
Organization: Carnegie Institute for Science
Fast, high efficiency and reproducible
Application Area:Recovery of DNA from ChIP samples
"This product design is much better than QIAGEN and can efficiently recovery small amount of DNA in less than 10ul, adaptable for downstream application. Fast process and high yield "
The DNA Clean & Concentrator™-5 product provides purification of up to 5 µg DNA from PCR, endonuclease digestions, DNA modification reactions, isotope/fluorescence labeling reactions, etc.
This product facilitate the removal of DNA polymerases, modifying enzymes, RNA polymerases, ligases, kinases, nucleases, phosphatases, and restriction endonucleases, as well as free dNTPs and their analogs including radiolabeled and fluorescent derivatives. Eluted DNA is suitable for PCR, arrays, ligation, sequencing, etc.