Dianthus for challenging affinity screening by NanoTemper Technologies

Manufacturer NanoTemper Technologies  |  Available Worldwide
5.0
/
5.0
  |  1 reviews
Dianthus is a plate-based, microfluidics-free affinity screening platform that measures under controlled equilibrium conditions and in-solution. With two biophysical modalities - Spectral Shift and TRIC - Dianthus excels at challenging interactions that involve molecules like PROTAC ternary complexes, intrinsically disordered proteins, and fragment libraries.


Dianthus for challenging affinity screening by NanoTemper Technologies product image
Dianthus for challenging affinity screening
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Average Rating: 5.0
1 Scientist has reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2022

  • Organization: Self-Employed



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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It was awesome and the right one to use
Rating: 5.0

  • Application Area: Protein characterization, Amino acid, tissue, nucleic acid

"The equipment in giving an effective and accurate on terms of result"

Review date: 26 Sep 2022 | Dianthus for challenging affinity screening

Dianthus is a plate-based and microfluidics-free affinity screening platform. Measurements are performed in solution and are mass-independent — ideal for succeeding at demanding screening campaigns With two methods for measuring molecular interactions, Spectral Shift and TRIC, Dianthus delivers high-quality data and requires less assay development to give you results from real-life samples

Today, the most important drug targets are super challenging when it comes to affinity screening. Immobilization-dependent SPR struggles with applications involving PROTAC binary and ternary complexes and intrinsically disordered proteins. These are precisely the applications where Dianthus excels

 

Here’s what makes Dianthus the perfect choice for challenging affinity screening campaigns:

  • High signal-to-noise ratio: Reliable affinity measurements
  • Mass independence: Measure binding with small and large molecules
  • Broad range of affinities: From picomolar to millimolar for detection of strong and weak binders
  • In-depth understanding of sample quality: Insights into aggregation induced by ligand

Dianthus' 384-well format and gRPC framework means it can be seamlessly integrated into many automation solutions that include robotic liquid handling and plate feeders for hours of uninterrupted and unattended operation

Product Overview

Dianthus for challenging affinity screening by NanoTemper Technologies product image

Dianthus for challenging affinity screening

Manufacturer NanoTemper Technologies  |  Available Worldwide

5.0 / 5.0 | 1 reviews