The Guava® Caspase 3/7 and 8 Assays employ a FLICA (Fluorescent Labeled Inhibitor of Caspases) reagent that specifically identifies active caspase 3 and 7 molecules or caspase 8 molecules. Non-cytotoxic, cell permeant dyes elimiate lysis and permeabilization procedures. Each FLICA is comprised of three subunits: A caspase-specific amino acid inhibitor containing a recognition sequence for caspase 3/7 (DEVD) or caspase 8 (LETD); a fluoromethylketone moiety (FMK) that forms a covalent linkage with... Read more
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Caspase 3/7 Reagent Kit (100 tests)
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Average Rating: 3.9
2 Scientists have reviewed this product
Status:
Reviewer
Member since: 2022
Organization: Aparmit Foundation
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- Ease of use
- After sales service
- Value for money
Good to use and better results
Rating: 4.0
Application Area: It used to measure activity using a caspase-specific inhibitor sequence linked to a fluorescent prob
"The Caspase 3/7 Reagent Kit is used to detect the activity of caspase-3 and caspase-7, which are enzymes that play important roles in apoptosis (programmed cell death) These kits use different methods to detect caspase activity, so you may want to choose one that best fits your experimental needs. It is easy to used use and but this product is avarage in value of money."
Review date: 24 Jul 2023 | Caspase 3/7 Reagent Kit (100 tests)
Status:
Reviewer Member since: 2011
Organization: UNIVERSITY OF MARYLAND
-
- Ease of use
- After sales service
- Value for money
Rating: 3.7
Review date: 01 Jul 2011 | Caspase 3/7 Reagent Kit (100 tests)
"Works well but expensive."
Review date: 01 Jul 2011 | Caspase 3/7 Reagent Kit (100 tests)
The Guava® Caspase 3/7 and 8 Assays employ a FLICA (Fluorescent Labeled Inhibitor of Caspases) reagent that specifically identifies active caspase 3 and 7 molecules or caspase 8 molecules.
Non-cytotoxic, cell permeant dyes elimiate lysis and permeabilization procedures. Each FLICA is comprised of three subunits:
A caspase-specific amino acid inhibitor containing a recognition sequence for caspase 3/7 (DEVD) or caspase 8 (LETD); a fluoromethylketone moiety (FMK) that forms a covalent linkage with the active enzyme; and a carboxyfluorescein (FAM) reporter.
The nuclear DNA stain is also included in the assay to simultaneously evaluate membrane integrity and cell viability. For use with all instruments.
Non-cytotoxic, cell permeant dyes elimiate lysis and permeabilization procedures. Each FLICA is comprised of three subunits:
A caspase-specific amino acid inhibitor containing a recognition sequence for caspase 3/7 (DEVD) or caspase 8 (LETD); a fluoromethylketone moiety (FMK) that forms a covalent linkage with the active enzyme; and a carboxyfluorescein (FAM) reporter.
The nuclear DNA stain is also included in the assay to simultaneously evaluate membrane integrity and cell viability. For use with all instruments.
