Bioreagent & Bioanalytical tools
Biomarker assay kits
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The study of biomarkers allows to determine the toxicity and efficacy of new molecules and drugs. Bertin Bioreagent develops a wide range of bio-analytical tools targeting biomarkers involved in various fields such as diabetes, obesity, pain… It offers more than 40 referrals of assay kits (ELISA, EIA, enzymatic...) and 240 antibody references (monoclonal and polyclonal).
A comprehensive offer of best in class analysis tools dedicated to biomarkers:
- Commitment to quality & guaranteed performance
- 30 years of know-how in biomarker assays
- A complementary reagent range for streamlined workflows with Bertin Instruments
Related products:
- Pre-analytical tools
- Assay kits
- Antibodies
- Biotoxis qPCR detection kit
- Emulsion kits
Brochures
Biomarker detection: Kits and reagents
In this product brochure, Bertin Instruments introduces its comprehensive portfolio of top-class analysis tools dedicated to biomarkers.
Calcitonin gene-related peptide in complex biological matrices: Application to pain and inflammation studies
Calcitonin gene-related peptide (CGRP) has been identified as a key vasodilator neuropeptide involved in several pain and inflammation mechanisms. It is therefore important to be able to measure levels of this neuropeptide to better understand the mechanisms involved in chronic pain conditions.
This white paper describes a collection of studies using the Bertin Bioreagent CGRP kits to quantify CGRP in a range of biological samples for pain and inflammation studies.
Plasma levels of ghrelin, deacyl ghrelin and LEAP2 in children with obesity
Ghrelin is an octanoylated hormone produced by the gastrointestinal tract that regulates appetite and blood glucose. It can be deacylated in plasma, generating deacyl-ghrelin (DAG). DAG blocks some effects of ghrelin, but does not bind to the ghrelin receptor. LEAP2 is a recently discovered ghrelin receptor ligand that also blocks the effects of ghrelin. Other investigations showed that plasma levels of these hormones are altered in people with obesity, but levels in children with obesity have not been studied. This application note evaluates the fasting plasma levels of ghrelin, DAG and LEAP2 in children with normal weight (NW), overweight / obesity (OW / OB) and their association with different anthropometric and metabolic variables.
Measurement of plasma CGRP levels in pediatric migraine patients
Calcitonin gene-related peptide (CGRP) has been shown to be a biomarker of migraine in adults. CGRP causes dilatation of both peripheral and cerebral blood vessels. Baseline plasma CGRP levels are significantly higher in migraine adult patients than in healthy controls. Additionally, during a migraine attack, the plasma CGRP levels of both adult and pediatric patients increase and strongly correlate with headache intensity. In this study, the scientists explore whether CGRP could be a biomarker helping stratification of migrainous children, by studying the relation between plasma CGRP levels and the responses to anti-migraine therapies.
Biomarker research – Immuno-oncology, COVID-19, proteomics and more
Trends in biomarker discovery methods and novel techniques advancing research, clinical diagnostics and therapeutic development
Latest advances in biomarker research: SelectScience special feature
The latest research and new method downloads: multiplex assays, ELISA, proteomics, genomics, imaging and more
