Allegra X-5 Benchtop Centrifuge
Precision performance for clinical labs

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Maximum speed and capacity for high-throughput labs.
This air-cooled benchtop centrifuge was designed specifically for the clinical laboratory. The Allegra X-5 performs with endurance under the most exacting standards, offering enhanced productivity and reliability for almost any clinical sample preparation. Convenient, pre-bundled packages—including swinging bucket rotors and common adapters—get you up and running quickly. Or you can choose from a selection of optional adapters. The Allegra X-5 is ideal for serum, plasma and whole blood sample processing; protein precipitate, particulate and cell sedimentation; in-vitro cytotoxicity and receptor binding sample processing.
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This application note describes the use of automated Biomek methods for next generation sequencing on benign and cancerous colon cell lines. Exosomes are small microvesicles, derived from the late endosome, most often described in the literature to be less than 120 nm, released by all cell types, and proven to be involved in cancer metastasis. Exosomes contain proteins, lipids, and microRNA capable of regulating an assortment of target genes. The results of this experiment demonstrate the capabilities of Beckman Coulter instrumentation in producing high impact next generation sequencing data with only a single MiSeq sequencing run. This method can be used to identify potential biomarkers and measure differential expression against sample type.
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