Synple Chem
Automated Chemical Synthesis Platform

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Features:
5 x More efficient
- Fully automated organic synthesis
- 5 minutes to set up
- Frees your time to focus on more important experiments
Accurate & convenient
- Optimized reaction, no risk of human error
- Compact size (W 26 cm, H 36 cm, D 49 cm)
- Fast and easy orders through our web shop
70% Cost savings
- Considerably more economical than manual chemical synthesis due to lower personnel and reagent costs
No special training
- Easy to use, requires no detailed chemistry knowledge
- Modular system for a range of reactions at the press of a button
Enhanced safety
- Fully enclosed reaction
- User never exposed to chemicals
- Complies with latest safety standards
90% Less waste
- Fully optimized reaction sequence
- Uses minimum reagents and solvents, greatly reducing chemical waste
Synthesis in 4 simple steps
The platform consists of the Synple 2 chemical synthesizer and a range of reagent cartridges for different reactions. Simply add your starting material and the appropriate reagent cartridge to the synthesizer and press a button. The product is automatically generated, isolated, and purified in minutes – not hours as in manual synthesis.
Automated synthesis with SYNTHIA retrosynthesis software
SYNTHIA™ retrosynthesis software aids chemists in designing synthetic routes, offering ranked potential routes to target molecules, while Synple's cartridge-based synthesis technology automates chemical reactions commonly used in discovery chemistry. Merck KGaA, Darmstadt, Germany, discusses the integration of SYNTHIA retrosynthesis software with Synple Automated Synthesizer to streamline synthetic chemistry processes. It highlights the advancements in technology and automation, including robotic systems, machine learning algorithms, and virtual screening methods, which accelerate molecule discovery and synthesis while minimizing errors. There is also case study comparing different search configurations and demonstrates the quick and efficient synthesis of target molecules using both manual and automated approaches, showcasing the potential of this integrated workflow to accelerate the drug discovery process.
Accelerate your discovery with Synple 2
Accelerate your discovery with Synple 2: a fully automated organic chemical synthesizer that uses prefilled reagent cartridges to generate, isolate, and purify your research products for you – at the press of a button – in minutes. Say goodbye to hours of manual synthesis. See how Synple can keep your work flowing. Learn more about Synple 2 >>



















