Products & ReviewLife Sciences
SMARTvector Inducible Lentiviral shRNA
Available: Worldwide
Tightly controlled gene silencing with the most advanced and flexible single-vector inducible shRNA.
Description
Gene silencing guaranteed with state-of-the-art shRNA designs, and multiple promoter and reporter options.
Application NoteLife Sciences
SMARTvector™ shRNA technology: Enabling cell and gene therapies
Expression-based RNAi systems utilizing short hairpin RNA (shRNA) have shown great promise for silencing nearly any gene and providing protein-level knockdown for a prolonged period. However, there are reported toxicity issues associated with shRNA, and non-optimized scaffolds may result in low levels of target gene knockdown while inducing off-target silencing. The SMARTvector™ technology addresses these shortcomings by expressing the shRNA sequence from an optimized micro-RNA based scaffold.
