Shasta™ Single Cell System

We have entered a new era in single-cell NGS analysis! No longer are you limited to profiling just hundreds of cells and accessing only part of a cell’s rich genetic information. Shasta technologies have surpassed the boundaries of existing methods, enabling the detection of more biomarkers—splicing isoforms, gene fusions, and CNVs—in more cells than ever before.

This novel system can be used for a variety of applications:

• Perform high-throughput total RNA profiling with full gene-body coverage of up to 100,000 single cells per run
• Amplify the whole genome of up to 1,500 single cells per run
• Analyze full-length transcriptomes with SMART-Seq^® technology
• Create customized applications

The Shasta system offers its users many benefits compared to other single-cell NGS systems:

• Pre-validated applications for high-throughput single-cell whole-genome or transcriptome profiling
• Intuitive user interface for setting up custom NGS assays with just a few clicks
• Large-bore nozzle for unbiased cell isolation, even for challenging cell types such as primary cardiomyocytes
• Nanoliter-scale reaction options to reduce costs and make the most out of your precious samples
• Integrated optical system, allowing the identification of wells containing single cells for further processing

Discover novel biomarkers through our complete solution: a state-of-the-art, automated dispensing and imaging platform combined with well-validated NGS library prep chemistries and bioinformatics tools for comprehensive data analysis.

• First solution for high-throughput single-cell total RNA profiling with full gene-body coverage—Shasta Total RNA-Seq Kit
• First solution for high-throughput single-cell DNA-seq with whole-genome coverage—Shasta Whole-Genome Amplification Kit
• Your end-to-end solution to analyze sequencing data and discover hidden biomarkers without being a bioinformatics expert—Cogent™ NGS tools