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PX1 PCR Plate Sealer


The PX1 PCR plate sealer includes the heat sealing instrument with power cord, a single plate support block that fits both 96- and 384-well plates, and a sealing frame to aid in heat sealing.

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Average Rating 4.5

|2Scientists have reviewed this product

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Excellent quality and great outputs


Average Rating 4.7

Application Area:

To reduce the viscosity from the samples before PCR run

This is a new machine that we bought in our lab recently. I have learned to use this machine for the sealing the PCR plate and it actually works. Provides the better results as compare to the PCR plates run when you do the manual sealing. It reduces the viscosity and improves the amplification and error between the replicates. Happy to have it at my lab and will recommend to have in yours especially, if you are working in the field of qPCRs.

Review Date: 14 Dec 2020 | Bio-Rad

Average Rating 4.3

Application Area:

Sealing 384 plates with clear and aluminum heat seals

The sealer was very easy to set up and ready to seal pretty much out of the box. Works well, eliminates user error inherent in manual application of seals that leads to evaporation at corner and edge wells. My only complaint is the price of the seals, I would expect them to be cheaper than adhesive seals since we have to buy the sealer, and unfortunately they are not.

Review Date: 8 Dec 2014 | Bio-Rad

Use the PX1 PCR Plate Sealer for consistent, uniform sealing across the entire plate, minimizing evaporation during cycling. The small-footprint heat sealer is compatible with a wide range of PCR plates and different types of films and foils.

Features and Benefits

  • Ready to seal in less than 3 min
  • Support block holds both 96-and 384 well plates
  • Motorized drawer for insertion of plate and seal
  • Touch-screen interface allowing single button modification of temperature and time
  • Easy access to previously stored sealing protocols

The intuitive touch-screen interface of the PX1 PCR Plate Sealer shows instrument status, platen temperature, protocol name, set temperature, and time. Sealing protocols can be stored and easily edited. The sealer can be programmed to automatically shut down after a user-defined period of idle time. Touching the display after shutdown will reactivate the display and the sealer will begin heating to the last set temperature.

The semi-automated PX1 PCR Plate Sealer provides fast, consistent sealing, removing human variability and increasing reproducibility. Uniform sealing over the whole plate is particularly important for low-volume samples where small amounts of evaporation can have significant effect. In qPCR experiments, differential evaporation from wells can lead to large standard deviations in the number of quantification cycles (Cq).

Product Components

  • Heat sealing instrument
  • Plate support block for both 96- and 384-well plates
  • Sealing frame

Related Products

  • Optically Clear Heat Seals, for PCR and real-time PCR applications ( 1814030 )
  • Permanent Clear Heat Seals, nonpeelable, nonpierceable clear seals for PCR, water bath cycling, and sample disposal ( 1814035 )
  • Pierceable Foil Heat Seals for PCR and QX200™ Droplet Digital™ PCR System applications ( 1814040 )
  • Peelable Foil Heat Seals laminate/foil peelable seals for PCR and sample storage ( 1814045 )

Related Categories

  • PCR Plates
  • Heat Sealing Films and Foils
  • Thermal Cyclers
  • Real-Time PCR Detection Systems
  • Digital PCR

Online Resources

  • Suggested Heat Sealing Parameters
  • Amplification Plastics and Reagents Selection Guide
  • qPCR/Real-Time PCR
  • qPCR Instrumentation

Product Overview