MED64 Multi-electrode Array System
Bandwidth of 0.1Hz -10 kHz allows users to record several types of extracellular potentials. • Low-cut filter (High pass filter) with 0.1, 1, 10, and 100Hz cutoff. • High cut filter (Low pass filter) with 1, 2.5, 5, 7.5, and 10kHz cutoff. • Built-in 2-channel stimulator allows users to program and deliver complex stimulation sequences independently through any 2 electrodes. • USB connection to computer.SpecificationsHead Ampl…
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Bandwidth of 0.1Hz -10 kHz allows users to record several types of extracellular potentials.
• Low-cut filter (High pass filter) with 0.1, 1, 10, and 100Hz cutoff.
• High cut filter (Low pass filter) with 1, 2.5, 5, 7.5, and 10kHz cutoff.
• Built-in 2-channel stimulator allows users to program and deliver complex stimulation sequences independently through any 2 electrodes.
• USB connection to computer.
Specifications
Head Amplifier
Number of channels 64
Gain x 10
Bandwidth 0.1Hz-100 kHz (+0dB to -3dB)
Input impedance 100MΩ
Output impedance 10kΩ
Stimulator
Number of channels 2
Output format: Constant current
Maximum input voltage +/-4V
Maximum output current +/-200µA
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Main Amplifier
Number of channels 64
Gain 1-217
Bandwidth 0.1Hz-10 kHz (+0dB to -3dB)
Analog high cut filter 1, 2.5, 5, 7.5, 10kHz (-6dB/oct)
Analog low cut filter 0.1, 1, 10, 100Hz (-12dB/oct)
Input impedance 100 MΩ
Digitizer
Resolution 16 bit
Sampling rate 20kHz
Output: USB
The MED64 Multi‐Electrode Array System
The MED64 has become a popular platform for modeling human hereditary cardiomyopathies and drug screening, since hSC-CMs possess the same genetic background as primary human CMs and their pharmacology is presumably very similar. The goal of this application note is to describe how to set up experiments with human stem cell-derived cardiomyocytes (hSC-CMs), acquire relevant data, and extract the data for presentation or publication.
