Avanti® Polar Lipids MPLA (PHAD®)
Monophosphoryl Lipid A (Synthetic) (PHAD®), powder

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Vaccination is well-accepted as an effective method to prevent infections by mounting pathogen-specific immune responses prior to the infection. Usually, immunization with vaccine antigens alone is not able to induce robust or long-lasting immune responses — resulting in failure of protective immunity against infections. Thus, adjuvants are required to enhance cellular or humoral immune responses upon immunization. Because vaccine adjuvants using Lipid A have proven to be safe and effective in inducing Th-1 type immune responses to heterologous proteins in animal and human vaccines, Avanti developed Phosphorylated HexaAcyl Disaccharide (PHAD®), the first fully synthetic monophosphoryl Lipid A available for use as an adjuvant in human vaccines.
Packaging
- 2 mL Amber Glass Crimp Cap Vial (699800P-1mg)
- 2 mL Amber Glass Crimp Cap Vial (699800P-5mg)
Other Notes
- For R&D use only. Not for drug, household, or other uses.
Brochures
Avanti's Mini-Extruder for LUV Preparation
Whether you specialize in lipidomics or lipids are simply a part of your research, you know the critical role lipids play and the inherent challenges they present. Discover more than 2,000 Avanti® products with >99% purity: from natural and synthetic phospholipids, to sphingolipids and sterols,.
Adjuvants to enhance cellular immune response to vaccines
Increase the effectiveness of human vaccines against infectious diseases such as COVID-19




















