Products & ReviewClinical Diagnostics

Atellica IM Soluble fms-like Tyrosine Kinase‑1 (sFlt‑1) and Placental Growth Factor (PlGF) Assays

Siemens HealthineersSMN 11200235, SMN 11200232, SMN 10997829, SMN 10997828Available: Western Europe, Eastern Europe, Asia, South America, Middle East

The Siemens Healthineers sFlt-1 and PlGF assays are valuable tools in assessing risk and managing pregnant women suspected of having preeclampsia. They are available on the Atellica IM, Atellica CI and ADVIA Centaur Immunoassay Systems. Not available for sale in USA.

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Description

Preeclampsia (PE) is a serious pregnancy complication with potentially life-threatening consequences for both mother and fetus. It is associated with an imbalance of two placental biomarkers: sFlt-1 and PlGF. The measurement of the sFlt-1/PlGF ratio provides additional insights into placental dysfunction which can help improve the assessment of PE risk.

The Atellica IM sFlt-1 and PlGF assays deliver robust clinical performance for preeclampsia diagnosis, short-term risk prediction, and prognosis of adverse outcomes, including preterm delivery. By integrating these assays into clinical practice, healthcare teams can make timely and evidence-based decisions, strengthening confidence at critical points in PE care.

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